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Merge branch 'main' of https://github.com/secrierlab/EMT into main
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guidmt committed Jul 23, 2021
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Expand Up @@ -13,6 +13,10 @@ This folder contains the code to reconstruct the EMT trajectory of the bulk RNA-
- **projection_EMT_trajectory_MCF10A_to_TCGA.R:** main script to reconstruct the EMT trajectory of TCGA samples using as reference single-cell MCF10 data and their defined EMT pseudospace (trajectory). This script performs also several exploratory analysis.
- **namescript2.R:**
- **run_analysis_pseudospace_TCGA_MET500.R:** procedure to quantify the EMT trajectory using TCGA and MET500 data
- **projection_EMT_trajectory_MCF10A_to_CCLE.R:** main script to reconstruct the EMT trajectory of CCLE samples using as reference single-cell MCF10 data and their defined EMT pseudospace (trajectory). This script performs also several exploratory analysis. This script combine also EMT states with the information of the metastatic potential.
- **knnForCCLE_MCF.R:** functions useful to run projection_EMT_trajectory_MCF10A_to_CCLE.R
- **petalChartGMT.R:** functions useful to run projection_EMT_trajectory_MCF10A_to_CCLE.R


## HMM_macrostates_EMT
This folder contains the code to perform the segmentation of the EMT trajectory and to identify the macrostates of EMT
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