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#ifndef _WZ_STATS_H_ | ||
#define _WZ_STATS_H_ | ||
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#include <math.h> | ||
#include <stdlib.h> | ||
#include <stdio.h> | ||
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#define MAXIT 100 | ||
#define EPS 3.0e-7 | ||
#define FPMIN 1.0e-30 | ||
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typedef enum{HOMOREF = 0, HET = 1, HOMOVAR = 2} Genotype; | ||
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double binom_pval(int s, int n, double p); | ||
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double pval2qual(double pval); | ||
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double varcall_pval(int kr, int kv, double error, double mu, double contam); | ||
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double genotype_lnlik(Genotype genotype, int kr, int kv, double error, double contam); | ||
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double somatic_lnlik(int kr, int kv, double error); | ||
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double fisher_exact(int n11, int n12, int n21, int n22, double *_left, double *_right, double *two); | ||
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/* double ln_beta_incdiff_kernel(double p1, double p2, int a, int b); */ | ||
double inconsist_score(int kr_tumor, int kv_tumor, int kr_normal, int kv_normal, double mu, double error); | ||
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double ln_sum2(double ln1, double ln2); | ||
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double ln_sum3(double ln1, double ln2, double ln3); | ||
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double ln_substract(double ln1, double ln2); | ||
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double ln_binom_kernel(double p, int a, int b); | ||
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double ln_beta_incdiff_kernel(double p1, double p2, int a, int b); | ||
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double somatic_posterior(int kr_t, int kv_t, int kr_n, int kv_n, double error, double mu, double mu_somatic, double contam); | ||
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double beta_binomial(int k, int n, double a, double b); | ||
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#endif |
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#ifndef _WQUEUE_H_ | ||
#define _WQUEUE_H_ | ||
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#include <pthread.h> | ||
#include <stdint.h> | ||
#include <stdlib.h> | ||
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/* | ||
by [email protected] | ||
block get when empty | ||
block put when full | ||
example usage: | ||
*/ | ||
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#define DEFINE_WQUEUE(name, _wqueue_elem_t) \ | ||
typedef struct { \ | ||
uint32_t size; \ | ||
_wqueue_elem_t *data; \ | ||
uint32_t head, tail; \ | ||
int full, empty; \ | ||
pthread_mutex_t mut; \ | ||
pthread_cond_t not_full, not_empty; \ | ||
} wqueue_##name##_t; \ | ||
static inline wqueue_##name##_t *wqueue_init_##name(uint32_t size) { \ | ||
wqueue_##name##_t *q = calloc(1, sizeof(wqueue_##name##_t)); \ | ||
q->empty = 1; \ | ||
q->size = size; \ | ||
q->data = calloc(size, sizeof(_wqueue_elem_t)); \ | ||
pthread_mutex_init(&q->mut, NULL); \ | ||
pthread_cond_init(&q->not_full, NULL); \ | ||
pthread_cond_init(&q->not_empty, NULL); \ | ||
return q; \ | ||
} \ | ||
static inline void wqueue_destroy_##name(wqueue_##name##_t *q) { \ | ||
free(q->data); \ | ||
pthread_mutex_destroy(&q->mut); \ | ||
pthread_cond_destroy(&q->not_full); \ | ||
pthread_cond_destroy(&q->not_empty); \ | ||
free(q); \ | ||
} \ | ||
static inline void wqueue_get_##name(wqueue_##name##_t *q, \ | ||
_wqueue_elem_t *e) { \ | ||
pthread_mutex_lock(&q->mut); \ | ||
while(q->empty) pthread_cond_wait(&q->not_empty, &q->mut); \ | ||
*e = q->data[q->head++]; \ | ||
if (q->head == q->size) q->head = 0; \ | ||
if (q->head == q->tail) q->empty = 1; \ | ||
q->full = 0; \ | ||
pthread_mutex_unlock(&q->mut); \ | ||
pthread_cond_signal(&q->not_full); \ | ||
} \ | ||
static inline void wqueue_put_##name(wqueue_##name##_t *q, \ | ||
_wqueue_elem_t *e) { \ | ||
pthread_mutex_lock(&q->mut); \ | ||
while(q->full) pthread_cond_wait(&q->not_full, &q->mut); \ | ||
q->data[q->tail++] = *e; \ | ||
if (q->tail == q->size) q->tail = 0; \ | ||
if (q->head == q->tail) q->full = 1; \ | ||
q->empty = 0; \ | ||
pthread_mutex_unlock(&q->mut); \ | ||
pthread_cond_signal(&q->not_empty); \ | ||
} \ | ||
static inline void wqueue_put2_##name(wqueue_##name##_t *q, \ | ||
_wqueue_elem_t e) { \ | ||
pthread_mutex_lock(&q->mut); \ | ||
while(q->full) pthread_cond_wait(&q->not_full, &q->mut); \ | ||
q->data[q->tail++] = e; \ | ||
if (q->tail == q->size) q->tail = 0; \ | ||
if (q->head == q->tail) q->full = 1; \ | ||
q->empty = 0; \ | ||
pthread_mutex_unlock(&q->mut); \ | ||
pthread_cond_signal(&q->not_empty); \ | ||
} | ||
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#define wqueue_t(name) wqueue_##name##_t | ||
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#define wqueue_init(name, size) wqueue_init_##name(size) | ||
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#define wqueue_destroy(name, q) wqueue_destroy_##name(q) | ||
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#define wqueue_get(name, q, e) wqueue_get_##name(q, e) | ||
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#define wqueue_put(name, q, e) wqueue_put_##name(q, e) | ||
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#define wqueue_put2(name, q, e) wqueue_put2_##name(q, e) | ||
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#endif |
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#ifndef _WZ_STR_H_ | ||
#define _WZ_STR_H_ | ||
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#include <stdio.h> | ||
#include <stdarg.h> | ||
#include <ctype.h> | ||
#include "kstring.h" | ||
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#define kstring_init(s) kstring_t (s); (s).s=0; (s).m=(s).l=0; | ||
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#define _WZ_STRLEN 100 | ||
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static inline char* | ||
wasprintf(const char *fmt, ...) { | ||
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char *s = malloc(_WZ_STRLEN); /* default length */ | ||
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va_list args; | ||
va_start(args, fmt); | ||
int l = vsnprintf(s, _WZ_STRLEN, fmt, args); /* if fail, l is the number characters that would've been written */ | ||
if (l >= _WZ_STRLEN) { | ||
s = realloc(s, l+1); | ||
va_start(args, fmt); | ||
vsnprintf(s, l+1, fmt, args); | ||
} | ||
va_end(args); | ||
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return s; | ||
} | ||
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static inline int strcount_char(char *s, char c) { | ||
int i, n=0; | ||
for (i=0; s[i]; ++i) | ||
if (s[i] == c) | ||
++n; | ||
return n; | ||
} | ||
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static inline void ensure_number(char *s) { | ||
int i; | ||
for (i=0;s[i];++i) { | ||
if (!isdigit(s[i]) && s[i]!='.') { | ||
fprintf(stderr, "[%s:%d] Trying to convert nondigit string to number: %s\n", __func__, __LINE__, s); | ||
fflush(stderr); | ||
exit(1); | ||
} | ||
} | ||
} | ||
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#endif /* _WZ_STR_H_ */ |
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