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Quick analysis of cell type compostition based on Nanopore cfDNA methylome

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cfNDA_celltype

Analysis of originating cell type composition based on Nanopore cfDNA methylome The main function is in the housman_test_cfDNA.R file. It is based on the publication of Houseman et al.:

Houseman, E.A., Accomando, W.P., Koestler, D.C. et al. DNA methylation arrays as surrogate measures of cell mixture distribution. BMC Bioinformatics 13, 86 (2012). https://doi.org/10.1186/1471-2105-13-86

An example use is shown in the data_analysis reproduce.R, which shows how to use it with a set of cfDNA data.

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Quick analysis of cell type compostition based on Nanopore cfDNA methylome

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