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Modeling mesoderm invagination in the Drosophila embryo with tyssue

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Invagination

Sample output from the model

DOI

This is a mesoderm invagination simulation package for the article:

Mechanical impact of epithelial−mesenchymal transition on epithelial morphogenesis in Drosophila

Mélanie Gracia, Sophie Theis, Amsha Proag, Guillaume Gay, Corinne Benassayag, and Magali Suzanne https://www.nature.com/articles/s41467-019-10720-0

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Dependencies

  • python > 3.6
  • tyssue >= 0.3.3

Installation

This package is based on the tyssue library and its dependencies.

The recommanded installation route is to use the conda package manager. You can get a conda distribution for your OS at https://www.anaconda.com/download . Make sure to choose a python 3.6 version. Once you have installed conda, you can install tyssue with:

$ conda install -c conda-forge tyssue

You can then download and install invagination from github:

  • with git:
$ git clone https://github.com/DamCB/invagination.git
$ cd invagination
$ python setup.py install

Licence

This work is free software, published under the MPLv2 licence, see LICENCE for details.

© The article authors -- all rights reserved

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Modeling mesoderm invagination in the Drosophila embryo with tyssue

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