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Benchmarking examples of lefser against LEfSe and microbiomeMarker

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This repository contains all the scripts (hyper-linked) to create Figures and Tables in the lefser manuscript.

Figures

  • Figure 1
    • Figure 1A. CRC data analysis with lefser
    • Figure 1B. CRC data analysis with LEfSe in barplot
    • Figure 1C. CRC data analysis with lefser in histogram
    • Figure 1D. CRC data analysis with lefser in cladogram

Supplementary Figures

  • Supplementary Figure 1

    • Supplementary Figure 1A. CRC data analysis with the original algorithm
    • Supplementary Figure 1B. CRC data analysis without noise addition and bootstrap
  • Supplementary Figure 2

    • Supplementary Figure 2A. Gingival data analysis with LEfSe bootstrap iterations (only 17 features)
    • Supplementary Figure 2B. Gingival data analysis comparing LEfSe bootstrap iterations and lefser (only 17 features)
  • Supplementary Figure 3

    • Supplementary Figure 3A. CRC data analysis with microbiomeMarker
    • Supplementary Figure 3B. Venn diagram of the CRC data analysis results
  • Supplementary Figure 4
    Benchmarking using the microbiome dataset (gingival data) with a ground truth

    • Figure 4A. Enrichment results
    • Figure 4B. Differences between putative TPs and FPs at different thresholds
  • Supplementary Figure 5

    • Supplementary Figure 4A. Mice data analysis with lefser
    • Supplementary Figure 4B. Mice data analysis with LEfSe
    • Supplementary Figure 4C. Mice data analysis with microbiomeMarker
    • Supplementary Figure 4D. Venn diagram of the mice data analysis results

Supplementary Tables

  • Supplementary Table 1. LEfSe bootstrap iteration summary with strict thresholds (data for Supplementary Figure 2)

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