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Merge pull request #7 from ncbi/master
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r78v10a07 authored Apr 16, 2019
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Expand Up @@ -5,7 +5,7 @@ BAMscale

BAMscale is a one-step tool for either 1) quantifying and normalizing the coverage of peaks or 2) generated scaled BigWig files for easy visualization of commonly used DNA-seq capture based methods.

For detailed information, visit the [wiki](https://github.com/pongorlorinc/BAMscale/wiki) page
For detailed information, visit the [wiki](https://github.com/ncbi/BAMscale/wiki) page

## Reference

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### libBigWig
Clone the libBigWig repository from GitHub: https://github.com/dpryan79/libBigWig

git clone https://github.com/dpryan79/libBigWig.git

Compile it and set the environment variables for BAMscale

cd libBigWig/
make
export LIBBIGWIG_DIR=`pwd`
export CPPFLAGS="-I $LIBBIGWIG_DIR"
export LDFLAGS="-L $LIBBIGWIG_DIR -Wl,-rpath,$LIBBIGWIG_DIR"

## Installation

After compiling the libBigWig library and samtools (if not already installed) clone the BAMscale from GitHub

git clone https://github.com/ncbi/BAMscale.git

and go to the BAMscale folder to compile the program:

cd BAMscale/
make

A bin folder will be created with the BAMscale executable.

## Usage

### Peak quantification
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