MutEx - a mutual exclusion and co-occurence empirical test

Algorithm to estimate the significance of a mutual exclusive pattern or co-occurrence

Citations

This python implementation has a citable DOI from Zenodo. Click on the badge for different citation styles:

The MutEx algorithm is described in detail in the PhD Thesis "Analysis and visualization of multidimensional cancer genomics data" : http://www.tdx.cat/handle/10803/301436. The same algorithm is also implemented and directly usable in the Gitools software package: http://www.gitools.org

The algorithm itself has first been used in the following publication: Rubio-Perez, Tamborero, Schroeder, Antolín, Deu-Pons, Perez-Llamas, Mestres, Gonzalez-Perez and Lopez-Bigas. In Silico Prescription of Anticancer Drugs to Cohorts of 28 Tumor Types Reveals Targeting Opportunities

Python dependencies

• scipy 0.17 or higher

• pandas 0.17 or higher

• numpy 1.10.4

• joblib

• multiprocessing