rp07 - RNApuzzle ready

mmagnus · May 18, 2017 · 993120b · 993120b
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diff --git a/rp07/7_0_soluton_4r4v_rpr.pdb b/rp07/7_0_soluton_4r4v_rpr.pdb
diff --git a/rp07/7_Adamiak_1_rpr.pdb b/rp07/7_Adamiak_1_rpr.pdb
diff --git a/rp07/7_Adamiak_2_rpr.pdb b/rp07/7_Adamiak_2_rpr.pdb
diff --git a/rp07/7_Adamiak_3_rpr.pdb b/rp07/7_Adamiak_3_rpr.pdb
diff --git a/rp07/7_Adamiak_4_rpr.pdb b/rp07/7_Adamiak_4_rpr.pdb
diff --git a/rp07/7_Adamiak_5_rpr.pdb b/rp07/7_Adamiak_5_rpr.pdb
diff --git a/rp07/7_Bujnicki_1_rpr.pdb b/rp07/7_Bujnicki_1_rpr.pdb
diff --git a/rp07/7_Bujnicki_2_rpr.pdb b/rp07/7_Bujnicki_2_rpr.pdb
diff --git a/rp07/7_Bujnicki_3_rpr.pdb b/rp07/7_Bujnicki_3_rpr.pdb
diff --git a/rp07/7_Bujnicki_4_rpr.pdb b/rp07/7_Bujnicki_4_rpr.pdb
diff --git a/rp07/7_Bujnicki_5_rpr.pdb b/rp07/7_Bujnicki_5_rpr.pdb
diff --git a/rp07/7_Bujnicki_6_rpr.pdb b/rp07/7_Bujnicki_6_rpr.pdb
diff --git a/rp07/7_Bujnicki_7_rpr.pdb b/rp07/7_Bujnicki_7_rpr.pdb
diff --git a/rp07/7_Chen_10_rpr.pdb b/rp07/7_Chen_10_rpr.pdb
diff --git a/rp07/7_Chen_1_rpr.pdb b/rp07/7_Chen_1_rpr.pdb
diff --git a/rp07/7_Chen_2_rpr.pdb b/rp07/7_Chen_2_rpr.pdb
diff --git a/rp07/7_Chen_3_rpr.pdb b/rp07/7_Chen_3_rpr.pdb
diff --git a/rp07/7_Chen_4_rpr.pdb b/rp07/7_Chen_4_rpr.pdb
diff --git a/rp07/7_Chen_5_rpr.pdb b/rp07/7_Chen_5_rpr.pdb
diff --git a/rp07/7_Chen_6_rpr.pdb b/rp07/7_Chen_6_rpr.pdb
diff --git a/rp07/7_Chen_7_rpr.pdb b/rp07/7_Chen_7_rpr.pdb
diff --git a/rp07/7_Chen_8_rpr.pdb b/rp07/7_Chen_8_rpr.pdb
diff --git a/rp07/7_Chen_9_rpr.pdb b/rp07/7_Chen_9_rpr.pdb
diff --git a/rp07/7_Das_1_rpr.pdb b/rp07/7_Das_1_rpr.pdb
diff --git a/rp07/7_Das_2_rpr.pdb b/rp07/7_Das_2_rpr.pdb
diff --git a/rp07/7_Das_3_rpr.pdb b/rp07/7_Das_3_rpr.pdb
diff --git a/rp07/7_Das_4_rpr.pdb b/rp07/7_Das_4_rpr.pdb
diff --git a/rp07/7_Das_5_rpr.pdb b/rp07/7_Das_5_rpr.pdb
diff --git a/rp07/7_Das_6_rpr.pdb b/rp07/7_Das_6_rpr.pdb
diff --git a/rp07/7_Das_7_rpr.pdb b/rp07/7_Das_7_rpr.pdb
diff --git a/rp07/7_Das_8_rpr.pdb b/rp07/7_Das_8_rpr.pdb
diff --git a/rp07/7_Ding_10_rpr.pdb b/rp07/7_Ding_10_rpr.pdb
diff --git a/rp07/7_Ding_1_rpr.pdb b/rp07/7_Ding_1_rpr.pdb
diff --git a/rp07/7_Ding_2_rpr.pdb b/rp07/7_Ding_2_rpr.pdb
diff --git a/rp07/7_Ding_3_rpr.pdb b/rp07/7_Ding_3_rpr.pdb
diff --git a/rp07/7_Ding_4_rpr.pdb b/rp07/7_Ding_4_rpr.pdb
diff --git a/rp07/7_Ding_5_rpr.pdb b/rp07/7_Ding_5_rpr.pdb
diff --git a/rp07/7_Ding_6_rpr.pdb b/rp07/7_Ding_6_rpr.pdb
diff --git a/rp07/7_Ding_7_rpr.pdb b/rp07/7_Ding_7_rpr.pdb
diff --git a/rp07/7_Ding_8_rpr.pdb b/rp07/7_Ding_8_rpr.pdb
diff --git a/rp07/7_Ding_9_rpr.pdb b/rp07/7_Ding_9_rpr.pdb
diff --git a/rp07/7_Dokholyan_1_rpr.pdb b/rp07/7_Dokholyan_1_rpr.pdb
diff --git a/rp07/7_Dokholyan_2_rpr.pdb b/rp07/7_Dokholyan_2_rpr.pdb
diff --git a/rp07/7_Major_10_rpr.pdb b/rp07/7_Major_10_rpr.pdb
diff --git a/rp07/7_Major_1_rpr.pdb b/rp07/7_Major_1_rpr.pdb
diff --git a/rp07/7_Major_2_rpr.pdb b/rp07/7_Major_2_rpr.pdb
diff --git a/rp07/7_Major_3_rpr.pdb b/rp07/7_Major_3_rpr.pdb
diff --git a/rp07/7_Major_4_rpr.pdb b/rp07/7_Major_4_rpr.pdb
diff --git a/rp07/7_Major_5_rpr.pdb b/rp07/7_Major_5_rpr.pdb
diff --git a/rp07/7_Major_6_rpr.pdb b/rp07/7_Major_6_rpr.pdb
diff --git a/rp07/7_Major_7_rpr.pdb b/rp07/7_Major_7_rpr.pdb
diff --git a/rp07/7_Major_8_rpr.pdb b/rp07/7_Major_8_rpr.pdb
diff --git a/rp07/7_Major_9_rpr.pdb b/rp07/7_Major_9_rpr.pdb
diff --git a/rp07/problem/7_Das_7_rpr.pdb b/rp07/problem/7_Das_7_rpr.pdb
diff --git a/rp07/problem/seqs.txt b/rp07/problem/seqs.txt
@@ -0,0 +1,3 @@
+> 7_Das_7_rpr A:1-185
+GCGCUGUGUCGCAAUCUGCGAAGGGCGUCGUCGGCCCAAGCGGUAGUAAGCAGGGAACUCACCUCCAAUGAAACACAUUGUCGUAGCAGUUGACUACUGUUAUGUGAUUGGUAGAGGCUAAGUGACGGUAUUGGCGUAAGCCAAUACCGCAGCACAGCACAAGCCCGCUUGCGAGAUUACAGCGC
+
diff --git a/rp07/readme.md b/rp07/readme.md
@@ -1,6 +1,92 @@
 RNA-Puzzle 07
 -----------------------------------------------------------------------------
 
+This is an intertwined dimer formed by an exchange of substrate helices. Since not all groups provided models of dimers, I (@mmagnus) focused on getting at least the chain A in order to be able to compare models to the native. It might not be what you exactly want dear user.
+
+```
+> 7_0_soluton_4r4v_rpr A:1-185
+GCGCUGUGUCGCAAUCUGCGAAGGGCGUCGUCGGCCCAAGCGGUAGUAAGCAGGGAACUCACCUCCAAUGAAACACAUUGUCGUAGCAGUUGACUACUGUUAUGUGAUUGGUAGAGGCUAAGUGACGGUAUUGGCGUAAGCCAAUACCGCAGCACAGCACAAGCCCGCUUGCGAGAUUACAGCGC
+
+> 7_Adamiak_1_rpr A:1-185
+GCGCUGUGUCGCAAUCUGCGAAGGGCGUCGUCGGCCCAAGCGGUAGUAAGCAGGGAACUCACCUCCAAUGAAACACAUUGUCGUAGCAGUUGACUACUGUUAUGUGAUUGGUAGAGGCUAAGUGACGGUAUUGGCGUAAGCCAAUACCGCAGCACAGCACAAGCCCGCUUGCGAGAUUACAGCGC
+```
+
 Manual:
 
 - Ding.. long list of atoms at the beggning
+
+Problem with `7_Das_7_rpr.pdb`
+
+```
+HEADER Generated with rna-pdb-tools
+HEADER ver v0.99-14-gca9e840-dirty 
+HEADER https://github.com/mmagnus/rna-pdb-tools 
+HEADER Thu May 18 18:48:13 2017
+REMARK 000 Missing atoms:
+REMARK 000  + P A <Residue A het=  resseq=156 icode= > residue # 156
+REMARK 000  + OP1 A <Residue A het=  resseq=156 icode= > residue # 156
+REMARK 000  + OP2 A <Residue A het=  resseq=156 icode= > residue # 156
+REMARK 000  + O5' A <Residue A het=  resseq=156 icode= > residue # 156
+```
+
+Rmsd of the A chain:
+
+    rna_calc_rmsd.py -t 7_0_soluton_4r4v_rpr.pdb --target_selection 'A:1-185' --model_selection 'A:1-185' *.pdb
+    rmsd_calc_rmsd_to_target
+    --------------------------------------------------------------------------------
+    method: all-atom-built-in
+    # of models: 52
+    7_0_soluton_4r4v_rpr.pdb 0.0 3956
+    7_Adamiak_1_rpr.pdb 29.04 3956
+    7_Adamiak_2_rpr.pdb 28.83 3956
+    7_Adamiak_3_rpr.pdb 30.74 3956
+    7_Adamiak_4_rpr.pdb 30.01 3956
+    7_Adamiak_5_rpr.pdb 28.39 3956
+    7_Bujnicki_1_rpr.pdb 42.52 3956
+    7_Bujnicki_2_rpr.pdb 60.63 3956
+    7_Bujnicki_3_rpr.pdb 26.14 3956
+    7_Bujnicki_4_rpr.pdb 24.89 3956
+    7_Bujnicki_5_rpr.pdb 24.89 3956
+    7_Bujnicki_6_rpr.pdb 26.15 3956
+    7_Bujnicki_7_rpr.pdb 26.93 3956
+    7_Chen_1_rpr.pdb 28.28 3956
+    7_Chen_2_rpr.pdb 34.36 3956
+    7_Chen_3_rpr.pdb 29.75 3956
+    7_Chen_4_rpr.pdb 27.75 3956
+    7_Chen_5_rpr.pdb 23.23 3956
+    7_Chen_6_rpr.pdb 29.07 3956
+    7_Chen_7_rpr.pdb 29.12 3956
+    7_Chen_8_rpr.pdb 29.93 3956
+    7_Chen_9_rpr.pdb 33.37 3956
+    7_Chen_10_rpr.pdb 31.55 3956
+    7_Das_1_rpr.pdb 20.58 3956
+    7_Das_2_rpr.pdb 23.56 3956
+    7_Das_3_rpr.pdb 24.57 3956
+    7_Das_4_rpr.pdb 25.39 3956
+    7_Das_5_rpr.pdb 24.6 3956
+    7_Das_6_rpr.pdb 25.16 3956
+    7_Das_8_rpr.pdb 26.8 3956
+    7_Ding_1_rpr.pdb 29.27 3956
+    7_Ding_2_rpr.pdb 32.76 3956
+    7_Ding_3_rpr.pdb 31.81 3956
+    7_Ding_4_rpr.pdb 31.95 3956
+    7_Ding_5_rpr.pdb 29.79 3956
+    7_Ding_6_rpr.pdb 29.3 3956
+    7_Ding_7_rpr.pdb 29.97 3956
+    7_Ding_8_rpr.pdb 27.24 3956
+    7_Ding_9_rpr.pdb 26.8 3956
+    7_Ding_10_rpr.pdb 36.56 3956
+    7_Dokholyan_1_rpr.pdb 30.19 3956
+    7_Dokholyan_2_rpr.pdb 36.92 3956
+    7_Major_1_rpr.pdb 29.01 3956
+    7_Major_2_rpr.pdb 28.18 3956
+    7_Major_3_rpr.pdb 26.91 3956
+    7_Major_4_rpr.pdb 27.64 3956
+    7_Major_5_rpr.pdb 28.53 3956
+    7_Major_6_rpr.pdb 27.7 3956
+    7_Major_7_rpr.pdb 28.53 3956
+    7_Major_8_rpr.pdb 27.41 3956
+    7_Major_9_rpr.pdb 27.37 3956
+    7_Major_10_rpr.pdb 31.61 3956
+    # of atoms used: 3956
+    csv was created!  rmsds.csv
diff --git a/rp07/rmsds.csv b/rp07/rmsds.csv
@@ -0,0 +1,53 @@
+fn,rmsd_all
+7_0_soluton_4r4v_rpr.pdb,0.0 
+7_Adamiak_1_rpr.pdb,29.04 
+7_Adamiak_2_rpr.pdb,28.83 
+7_Adamiak_3_rpr.pdb,30.74 
+7_Adamiak_4_rpr.pdb,30.01 
+7_Adamiak_5_rpr.pdb,28.39 
+7_Bujnicki_1_rpr.pdb,42.52 
+7_Bujnicki_2_rpr.pdb,60.63 
+7_Bujnicki_3_rpr.pdb,26.14 
+7_Bujnicki_4_rpr.pdb,24.89 
+7_Bujnicki_5_rpr.pdb,24.89 
+7_Bujnicki_6_rpr.pdb,26.15 
+7_Bujnicki_7_rpr.pdb,26.93 
+7_Chen_1_rpr.pdb,28.28 
+7_Chen_2_rpr.pdb,34.36 
+7_Chen_3_rpr.pdb,29.75 
+7_Chen_4_rpr.pdb,27.75 
+7_Chen_5_rpr.pdb,23.23 
+7_Chen_6_rpr.pdb,29.07 
+7_Chen_7_rpr.pdb,29.12 
+7_Chen_8_rpr.pdb,29.93 
+7_Chen_9_rpr.pdb,33.37 
+7_Chen_10_rpr.pdb,31.55 
+7_Das_1_rpr.pdb,20.58 
+7_Das_2_rpr.pdb,23.56 
+7_Das_3_rpr.pdb,24.57 
+7_Das_4_rpr.pdb,25.39 
+7_Das_5_rpr.pdb,24.6 
+7_Das_6_rpr.pdb,25.16 
+7_Das_8_rpr.pdb,26.8 
+7_Ding_1_rpr.pdb,29.27 
+7_Ding_2_rpr.pdb,32.76 
+7_Ding_3_rpr.pdb,31.81 
+7_Ding_4_rpr.pdb,31.95 
+7_Ding_5_rpr.pdb,29.79 
+7_Ding_6_rpr.pdb,29.3 
+7_Ding_7_rpr.pdb,29.97 
+7_Ding_8_rpr.pdb,27.24 
+7_Ding_9_rpr.pdb,26.8 
+7_Ding_10_rpr.pdb,36.56 
+7_Dokholyan_1_rpr.pdb,30.19 
+7_Dokholyan_2_rpr.pdb,36.92 
+7_Major_1_rpr.pdb,29.01 
+7_Major_2_rpr.pdb,28.18 
+7_Major_3_rpr.pdb,26.91 
+7_Major_4_rpr.pdb,27.64 
+7_Major_5_rpr.pdb,28.53 
+7_Major_6_rpr.pdb,27.7 
+7_Major_7_rpr.pdb,28.53 
+7_Major_8_rpr.pdb,27.41 
+7_Major_9_rpr.pdb,27.37 
+7_Major_10_rpr.pdb,31.61 
diff --git a/rp07/seqs.txt b/rp07/seqs.txt
@@ -1,3 +1,6 @@
+> 7_0_soluton_4r4v_rpr A:1-185
+GCGCUGUGUCGCAAUCUGCGAAGGGCGUCGUCGGCCCAAGCGGUAGUAAGCAGGGAACUCACCUCCAAUGAAACACAUUGUCGUAGCAGUUGACUACUGUUAUGUGAUUGGUAGAGGCUAAGUGACGGUAUUGGCGUAAGCCAAUACCGCAGCACAGCACAAGCCCGCUUGCGAGAUUACAGCGC
+
 > 7_Adamiak_1_rpr A:1-185
 GCGCUGUGUCGCAAUCUGCGAAGGGCGUCGUCGGCCCAAGCGGUAGUAAGCAGGGAACUCACCUCCAAUGAAACACAUUGUCGUAGCAGUUGACUACUGUUAUGUGAUUGGUAGAGGCUAAGUGACGGUAUUGGCGUAAGCCAAUACCGCAGCACAGCACAAGCCCGCUUGCGAGAUUACAGCGC
 
@@ -48,34 +51,34 @@ GCGCUGUGUCGCAAUCUGCGAAGGGCGUCGUCGGCCCAAGCGGUAGUAAGCAGGGAACUCACCUCCAAUGAAACACAUUG
 > 7_Bujnicki_7_rpr B:1-185
 GCGCUGUGUCGCAAUCUGCGAAGGGCGUCGUCGGCCCAAGCGGUAGUAAGCAGGGAACUCACCUCCAAUGAAACACAUUGUCGUAGCAGUUGACUACUGUUAUGUGAUUGGUAGAGGCUAAGUGACGGUAUUGGCGUAAGCCAAUACCGCAGCACAGCACAAGCCCGCUUGCGAGAUUACAGCGC
 
-> 7_Chen_10_rpr B:1-185
+> 7_Chen_10_rpr A:1-185
 GCGCUGUGUCGCAAUCUGCGAAGGGCGUCGUCGGCCCAAGCGGUAGUAAGCAGGGAACUCACCUCCAAUGAAACACAUUGUCGUAGCAGUUGACUACUGUUAUGUGAUUGGUAGAGGCUAAGUGACGGUAUUGGCGUAAGCCAAUACCGCAGCACAGCACAAGCCCGCUUGCGAGAUUACAGCGC
 
-> 7_Chen_1_rpr U:1-185
+> 7_Chen_1_rpr A:1-185
 GCGCUGUGUCGCAAUCUGCGAAGGGCGUCGUCGGCCCAAGCGGUAGUAAGCAGGGAACUCACCUCCAAUGAAACACAUUGUCGUAGCAGUUGACUACUGUUAUGUGAUUGGUAGAGGCUAAGUGACGGUAUUGGCGUAAGCCAAUACCGCAGCACAGCACAAGCCCGCUUGCGAGAUUACAGCGC
 
-> 7_Chen_2_rpr B:1-185
+> 7_Chen_2_rpr A:1-185
 GCGCUGUGUCGCAAUCUGCGAAGGGCGUCGUCGGCCCAAGCGGUAGUAAGCAGGGAACUCACCUCCAAUGAAACACAUUGUCGUAGCAGUUGACUACUGUUAUGUGAUUGGUAGAGGCUAAGUGACGGUAUUGGCGUAAGCCAAUACCGCAGCACAGCACAAGCCCGCUUGCGAGAUUACAGCGC
 
-> 7_Chen_3_rpr B:1-185
+> 7_Chen_3_rpr A:1-185
 GCGCUGUGUCGCAAUCUGCGAAGGGCGUCGUCGGCCCAAGCGGUAGUAAGCAGGGAACUCACCUCCAAUGAAACACAUUGUCGUAGCAGUUGACUACUGUUAUGUGAUUGGUAGAGGCUAAGUGACGGUAUUGGCGUAAGCCAAUACCGCAGCACAGCACAAGCCCGCUUGCGAGAUUACAGCGC
 
-> 7_Chen_4_rpr B:1-185
+> 7_Chen_4_rpr A:1-185
 GCGCUGUGUCGCAAUCUGCGAAGGGCGUCGUCGGCCCAAGCGGUAGUAAGCAGGGAACUCACCUCCAAUGAAACACAUUGUCGUAGCAGUUGACUACUGUUAUGUGAUUGGUAGAGGCUAAGUGACGGUAUUGGCGUAAGCCAAUACCGCAGCACAGCACAAGCCCGCUUGCGAGAUUACAGCGC
 
-> 7_Chen_5_rpr B:1-185
+> 7_Chen_5_rpr A:1-185
 GCGCUGUGUCGCAAUCUGCGAAGGGCGUCGUCGGCCCAAGCGGUAGUAAGCAGGGAACUCACCUCCAAUGAAACACAUUGUCGUAGCAGUUGACUACUGUUAUGUGAUUGGUAGAGGCUAAGUGACGGUAUUGGCGUAAGCCAAUACCGCAGCACAGCACAAGCCCGCUUGCGAGAUUACAGCGC
 
-> 7_Chen_6_rpr B:1-185
+> 7_Chen_6_rpr A:1-185
 GCGCUGUGUCGCAAUCUGCGAAGGGCGUCGUCGGCCCAAGCGGUAGUAAGCAGGGAACUCACCUCCAAUGAAACACAUUGUCGUAGCAGUUGACUACUGUUAUGUGAUUGGUAGAGGCUAAGUGACGGUAUUGGCGUAAGCCAAUACCGCAGCACAGCACAAGCCCGCUUGCGAGAUUACAGCGC
 
-> 7_Chen_7_rpr B:1-185
+> 7_Chen_7_rpr A:1-185
 GCGCUGUGUCGCAAUCUGCGAAGGGCGUCGUCGGCCCAAGCGGUAGUAAGCAGGGAACUCACCUCCAAUGAAACACAUUGUCGUAGCAGUUGACUACUGUUAUGUGAUUGGUAGAGGCUAAGUGACGGUAUUGGCGUAAGCCAAUACCGCAGCACAGCACAAGCCCGCUUGCGAGAUUACAGCGC
 
-> 7_Chen_8_rpr B:1-185
+> 7_Chen_8_rpr A:1-185
 GCGCUGUGUCGCAAUCUGCGAAGGGCGUCGUCGGCCCAAGCGGUAGUAAGCAGGGAACUCACCUCCAAUGAAACACAUUGUCGUAGCAGUUGACUACUGUUAUGUGAUUGGUAGAGGCUAAGUGACGGUAUUGGCGUAAGCCAAUACCGCAGCACAGCACAAGCCCGCUUGCGAGAUUACAGCGC
 
-> 7_Chen_9_rpr B:1-185
+> 7_Chen_9_rpr A:1-185
 GCGCUGUGUCGCAAUCUGCGAAGGGCGUCGUCGGCCCAAGCGGUAGUAAGCAGGGAACUCACCUCCAAUGAAACACAUUGUCGUAGCAGUUGACUACUGUUAUGUGAUUGGUAGAGGCUAAGUGACGGUAUUGGCGUAAGCCAAUACCGCAGCACAGCACAAGCCCGCUUGCGAGAUUACAGCGC
 
 > 7_Das_1_rpr A:1-185
@@ -98,9 +101,6 @@ GCGCUGUGUCGCAAUCUGCGAAGGGCGUCGUCGGCCCAAGCGGUAGUAAGCAGGGAACUCACCUCCAAUGAAACACAUUG
 > 7_Das_6_rpr A:1-185
 GCGCUGUGUCGCAAUCUGCGAAGGGCGUCGUCGGCCCAAGCGGUAGUAAGCAGGGAACUCACCUCCAAUGAAACACAUUGUCGUAGCAGUUGACUACUGUUAUGUGAUUGGUAGAGGCUAAGUGACGGUAUUGGCGUAAGCCAAUACCGCAGCACAGCACAAGCCCGCUUGCGAGAUUACAGCGC
 
-> 7_Das_7_rpr A:1-185
-GCGCUGUGUCGCAAUCUGCGAAGGGCGUCGUCGGCCCAAGCGGUAGUAAGCAGGGAACUCACCUCCAAUGAAACACAUUGUCGUAGCAGUUGACUACUGUUAUGUGAUUGGUAGAGGCUAAGUGACGGUAUUGGCGUAAGCCAAUACCGCAGCACAGCACAAGCCCGCUUGCGAGAUUACAGCGC
-
 > 7_Das_8_rpr A:1-185
 GCGCUGUGUCGCAAUCUGCGAAGGGCGUCGUCGGCCCAAGCGGUAGUAAGCAGGGAACUCACCUCCAAUGAAACACAUUGUCGUAGCAGUUGACUACUGUUAUGUGAUUGGUAGAGGCUAAGUGACGGUAUUGGCGUAAGCCAAUACCGCAGCACAGCACAAGCCCGCUUGCGAGAUUACAGCGC
Original file line number	Diff line number	Diff line change
		@@ -0,0 +1,3 @@
		> 7_Das_7_rpr A:1-185
		GCGCUGUGUCGCAAUCUGCGAAGGGCGUCGUCGGCCCAAGCGGUAGUAAGCAGGGAACUCACCUCCAAUGAAACACAUUGUCGUAGCAGUUGACUACUGUUAUGUGAUUGGUAGAGGCUAAGUGACGGUAUUGGCGUAAGCCAAUACCGCAGCACAGCACAAGCCCGCUUGCGAGAUUACAGCGC