Create README.md

README.md

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+# controlFreq
+The elaborate method for quantification of allele-specific expression. 
+
+This R-package performs **sample overdispersion estimation** from RNA spike-ins and technical replication. 
+
+## Installation:
+```
+devtools::install_github("gimelbrantlab/controlFreq")
+```
+Dependencies: [Qllelic](https://github.com/gimelbrantlab/Qllelic) 
+
+## Usage:
+Please see Wiki page connected to this repository.
+
+* For allelic bias test and differential AI test, see [Qllelic R-package](https://github.com/gimelbrantlab/Qllelic) functions and *["Replicate sequencing libraries are important for quantification of allelic imbalance", A.Mendelevich et.al](https://www.nature.com/articles/s41467-021-23544-8)*.
+
+* For data preprocessing procedure used in the paper and relevant recommendations, see [fastq2allelictabs](https://github.com/gimelbrantlab/fastq2allelictabs) repository.
+
+![pic](https://github.com/gimelbrantlab/fastq2allelictabs/blob/main/schemes/ControlFreq_for_GitHub.png)
+
+Figure was made in biorender.