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Use dragen 4.0.3, demux setting change, remove strand bias filter, and other updates

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@dufeiyu dufeiyu released this 21 Jun 07:05
· 21 commits to main since this release
b76f3fe
  1. Use dragen version 4.0.3
  2. Change dragen demux setting to trim 1 base from 5' and 2 bases from 3'
  3. Remove StrandBias filter
  4. Add "--qc-coverage-ignore-overlaps true" to dragen align command
  5. Add "-F x" to the bcftools merge command of MyeloseqHDAnalysis.wdl to preserves 'PASS' filter if one of the merged files has 'PASS'
  6. Several updates for filterHaloplex.py (refer to https://jira.wustl.edu/browse/CI-934)
  7. application.conf and WDL workflow updates to be compatible for dragen-3 and dragen-4