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#!/usr/bin/env python3 | ||
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import os | ||
import json | ||
import requests | ||
from datetime import datetime | ||
import yaml | ||
import click | ||
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def load_dataset(url): | ||
response = requests.get(url) | ||
full_data = json.loads(response.content) | ||
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return full_data | ||
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def prepare_header(data, url): | ||
return { | ||
"variant": { | ||
"nextstrain": data["nextstrainClade"], | ||
"pangolin": data["lineage"], | ||
"short": data["lineage"].lower().replace(".", "_"), | ||
"reference": { | ||
"address": url, | ||
"accessed_at": datetime.now().strftime("%Y-%m-%d %H:%M:%S"), | ||
}, | ||
} | ||
} | ||
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def prepare_mut(data): | ||
mut_dict = {} | ||
if data["nucSubstitutions"] != [""]: | ||
for item in data["nucSubstitutions"]: | ||
start_letter = item[0] | ||
end_letter = item[-1] | ||
number = int(item[1:-1]) | ||
mut_dict[number] = f"{start_letter}>{end_letter}" | ||
return {"mut": mut_dict} | ||
else: | ||
return "" | ||
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def prepare_del(data): | ||
del_dict = {} | ||
if data["nucDeletions"] != [""]: | ||
for item in data["nucDeletions"]: | ||
if "-" in item: | ||
start, end = map(int, item.split("-")) | ||
key = start | ||
value = str((end - start) * "-") | ||
else: | ||
key = int(item) | ||
value = "-" | ||
del_dict[key] = value | ||
return {"del": del_dict} | ||
else: | ||
return "" | ||
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def prepare_yaml(data, url): | ||
header = prepare_header(data, url) | ||
mut = prepare_mut(data) | ||
del_section = prepare_del(data) | ||
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output_data = header | ||
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if mut != "": | ||
output_data["mut"] = mut["mut"] | ||
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if del_section != "": | ||
output_data["del"] = del_section["del"] | ||
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return output_data | ||
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def process_dataset(full_data, outdir, url): | ||
if not os.path.exists(outdir): | ||
os.makedirs(outdir) | ||
for data in full_data.values(): | ||
output_data = prepare_yaml(data, url) | ||
with open(f"{outdir}/{output_data['variant']['short']}.yaml", "w") as yaml_file: | ||
yaml.dump(output_data, yaml_file, sort_keys=False) | ||
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@click.command( | ||
help="Generating a list of variants from nextstrain", | ||
epilog="This tool fetchs a JSON from Github", | ||
) | ||
@click.option( | ||
"-o", | ||
"--outdir", | ||
required=False, | ||
default="voc_nextstrain", | ||
type=str, | ||
help="The output directory for the YAML files", | ||
) | ||
@click.option( | ||
"-u", | ||
"--url", | ||
metavar="URL", | ||
required=False, | ||
default="https://raw.githubusercontent.com/corneliusroemer/pango-sequences/main/data/pango-consensus-sequences_summary.json", | ||
type=str, | ||
help="url to fetch the JSON from", | ||
) | ||
def generate_sigs_nextstrains(outdir, url): | ||
full_data = load_dataset(url) | ||
process_dataset(full_data, outdir, url) |
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