This package provides the analysis workflow for stoichiometry analysis of data from affinity purification experiments followed by mass spectrometry analysis (AP-MS) as published previously (Smits et al. 2013). The package is an extention of the DEP package and it requires tabular input as generated by MaxQuant with iBAQ quantification enabled. Functions are provided for the analysis and visualization. For scientists with limited experience in R, the package also contains wrapper functions that entail the complete analysis workflow.
Install and load the package
source("http://www.huber.embl.de/users/smits/install_DEPstoi.R")
library("DEPstoi")More information can be found in the vignette.