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AJG.Code review #11

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agodec
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@agodec agodec commented Nov 29, 2021

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@Christina-Straham Christina-Straham left a comment

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When I ran your code, I got the error "Error: object 'DNAme' not found." I would remove the install.package codes from the markdown or the reviewer will not be able to run the code!
FYI, I think you started working on Svetlana's version when it was merged to the main.

colnames(idh1_idh2) <- c("IDH")
compiled <- cbind(tet, idh1_idh2)
View(compiled) # scrolled through and identified the patient/sample number that had the mutations in both TET2 and IDH

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This is great! Wish I could have done this!

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@kate-t-48 kate-t-48 left a comment

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I think regarding your questions; the final TET2/IDH comparisons are looking at some Bayesian analyses to see which co-founders have the highest impact on methylation status. I believe the probe numbers are the number of statistically significant data points where the model (ie design 1/2/3) explains the methylation difference. Maybe?!

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5 participants