Project Title:

Developmental coupling of cerebral blood flow and fMRI fluctuations in youth

Brief Project Description:

831 participants from PNC were included. CBF (from ASL) and ALFF (from rs-FMRI) images were projected to the 2D surface space (fsaverage5), and vertexwise coupling occured via locally weighted regressions. Group level regressions relating coupling to age, sex, and executive functioning accuracy were performed.

Project Lead(s):

Erica Baller

Faculty Lead(s):

Ted Satterthwaite and Taki Shinohara

Analytic Replicator:

Azeez Adebimpe

Collaborators:

Erica B. Baller, M.D., M.S.a,b, Alessandra M. Valcarcel, Ph.D.c,⟊, Azeez Adebimpe, Ph.D.a,b, Aaron Alexander-Bloch, M.D., Ph.D.b, Zaixu Cui, Ph.D.a,b, Ruben C. Gur, Ph.D.b,d,f, Raquel E. Gur, M.D., Ph.D.b,d,f, Bart L. Larsen, Ph.D.a,b, Kristin A. Linn, Ph.D.c, Carly M. O’Donnell, B.A.c, Adam R. Pines, B.A.a,b, Armin Raznahan, Ph.D.e, David. R. Roalf, Ph.D.b, Valerie J. Sydnor, B.A.a,b, Tinashe M. Tapera, M.S.a,b, M. Dylan Tisdall, Ph.D.f, Simon Vandekar, Ph.D.g, Cedric H. Xia, M.D., Ph.D.a,b, John A. Detre, M.D.d, Russell T. Shinohara, Ph.D.c*, Theodore D. Satterthwaite, M.D., M.A.a,b*

Project Start Date:

My version - 10/2020

Current Project Status:

Completed - manuscript writing as of 7/2021

Dataset:

PNC

Github repo:

https://github.com/PennLINC/imco_pmacs/

Path to data on filesystem:

PMACS:/project/imco/ most work done in /project/imco/baller

Slack Channel:

#imco and #coupling

Zotero library:

IMCO

Current work products:

SOBP Poster 4/29/2021 - https://doi.org/10.1016/j.biopsych.2021.02.445

Code documentation:

Please download: https://github.com/PennLINC/imco_pmacs/blob/main/Project_markdown/IMCO_2021_Project_Age_Sex_Accuracy.docx (html too big to put on github!)