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ACCOST assigns statistical significance to differences in contact counts in Hi-C experiments. ACCOST uses a negative binomial to model the contact counts, and pools contacts at the same genomic distance to aid in estimating the mean and variance of the data. For details on how to run the software, see manual.html. For further information, contact Kate Cook <[email protected]>, Borislav Hristov <[email protected]>, or William Noble <[email protected]> Copyright 2019 University of Washington Licensed under the Apache License, Version 2.0 (the "License"); you may not use this file except in compliance with the License. You may obtain a copy of the License at http://www.apache.org/licenses/LICENSE-2.0 Unless required by applicable law or agreed to in writing, software distributed under the License is distributed on an "AS IS" BASIS, WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied. See the License for the specific language governing permissions and limitations under the License.
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