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ebouchut committed Mar 19, 2024
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1 change: 1 addition & 0 deletions faqs/glossary/index.html
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Expand Up @@ -3359,6 +3359,7 @@ <h1 id="glossary">Glossary<a class="headerlink" href="#glossary" title="Anchor l
<p><strong><span translate="no"><abbr title="chosen method for increased insulin dosing: (1) High Temp Basal or (2) Automatic Bolus with scheduled basal">Dosing Strategy</abbr></span></strong>&nbsp; (<abbr title="chosen method for increased insulin dosing: (1) High Temp Basal or (2) Automatic Bolus with scheduled basal">Dosing Strategy</abbr>): chosen method for increased insulin dosing: (1) High <abbr title="modify the scheduled basal rate for a pump">Temp Basal</abbr> or (2) <abbr title="provide a fraction of the recommended insulin automatically with each updated CGM reading (default 40%)">Automatic Bolus</abbr> with scheduled basal</p>
<p><strong><span translate="no"><abbr title="used to reboot a Nightscout Site">dynos</abbr></span></strong>&nbsp; (<abbr title="used to reboot a Nightscout Site">dynos</abbr>): used to reboot a <abbr title="a personal website used to view your glucose and diabetes management data, `Loop` can upload to `Nightscout`">Nightscout</abbr> Site</p>
<p><strong><span translate="no"><abbr title="radio-frequency device Loop uses to control Eros pods (aka. Gen 3) and older Medtronic pumps">EmaLink</abbr></span></strong>&nbsp; (<abbr title="radio-frequency device Loop uses to control Eros pods (aka. Gen 3) and older Medtronic pumps">EmaLink</abbr>): radio-frequency device <abbr title="With a capital L, Loop is one of several do-it-yourself artifical pancreas systems">Loop</abbr> uses to control Eros pods (aka. Gen 3) and older Medtronic pumps</p>
<p><strong><span translate="no"><abbr title="Endogenous Glucose Production: glucose produced by the body from its reserves (mainly glycogen in the liver)">EGP</abbr></span></strong>&nbsp; (<abbr title="Endogenous Glucose Production: glucose produced by the body from its reserves (mainly glycogen in the liver)">EGP</abbr>): Endogenous Glucose Production: glucose produced by the body from its reserves (mainly glycogen in the liver)</p>
<p><strong><span translate="no"><abbr title="record of pump events (bolus or temp basal) reported and used by Loop">Event History</abbr></span></strong>&nbsp; (<abbr title="record of pump events (bolus or temp basal) reported and used by Loop">Event History</abbr>): record of pump events (bolus or temp basal) reported and used by <abbr title="With a capital L, Loop is one of several do-it-yourself artifical pancreas systems">Loop</abbr></p>
<p><strong><span translate="no"><abbr title="your Loop app has a finite life, the app warns you starting 3 weeks before the expiration date">Expiration Date</abbr></span></strong>&nbsp; (<abbr title="your Loop app has a finite life, the app warns you starting 3 weeks before the expiration date">Expiration Date</abbr>): your <abbr title="With a capital L, Loop is one of several do-it-yourself artifical pancreas systems">Loop</abbr> app has a finite life, the app warns you starting 3 weeks before the expiration date</p>
<p><strong><span translate="no"><abbr title="used as part of the github Build Action method that enables building Loop without a Mac computer or Xcode">fastlane</abbr></span></strong>&nbsp; (<abbr title="used as part of the github Build Action method that enables building Loop without a Mac computer or Xcode">fastlane</abbr>): used as part of the github Build Action method that enables building <abbr title="With a capital L, Loop is one of several do-it-yourself artifical pancreas systems">Loop</abbr> without a Mac computer or <abbr title="program used to build an app">Xcode</abbr></p>
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4 changes: 2 additions & 2 deletions operation/algorithm/prediction/index.html
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Expand Up @@ -3733,7 +3733,7 @@ <h3 id="insulin-effect-on-blood-glucose">Insulin Effect on Blood Glucose<a class
<p>For this example, assuming a user’s blood glucose was 205 mg/dL at the time of insulin delivery, <abbr title="With a capital L, Loop is one of several do-it-yourself artifical pancreas systems">Loop</abbr> would predict a drop in blood glucose due to the two units delivered at 12 pm as shown in the figure below.</p>
<p><img alt="two unit example" src="../img/two_units.png" /></p>
<h3 id="scheduled-basal-rates">Scheduled Basal Rates<a class="headerlink" href="#scheduled-basal-rates" title="Anchor link to this Header on this Page">&para;</a></h3>
<p>In traditional basal/bolus pump therapy, basal rates are set to accommodate the user's endogenous glucose production (EGP) that causes blood glucose to rise. If a user's basal settings were exactly right in traditional pump therapy, the user would have perfectly flat blood glucose all day, all other factors being equal.</p>
<p>In traditional basal/bolus pump therapy, basal rates are set to accommodate the user's endogenous glucose production (<abbr title="Endogenous Glucose Production: glucose produced by the body from its reserves (mainly glycogen in the liver)">EGP</abbr>) that causes blood glucose to rise. If a user's basal settings were exactly right in traditional pump therapy, the user would have perfectly flat blood glucose all day, all other factors being equal.</p>
<p>In reality, people with type 1 diabetes, and their caregivers, know that basal settings are never exactly right. Every day is a little different, and a myriad of factors that affect blood glucose (e.g., including stress, hormones, sleep, etc.) may affect insulin needs. Some people have different basal profiles to accommodate these variations. Some people regularly tune and adjust their basal rates, and/or do so at their endocrinology clinic visits.</p>
<p>Since the <abbr title="With a capital L, Loop is one of several do-it-yourself artifical pancreas systems">Loop</abbr> algorithm assumes that the user-set basal rates are correct, it calculates the effect of insulin relative to scheduled basal rates. If basal rates are not entirely correct, <abbr title="With a capital L, Loop is one of several do-it-yourself artifical pancreas systems">Loop</abbr> can compensate a bit through the retrospective correction and blood glucose momentum effects, discussed later in this page.</p>
<p>The insulin delivery chart below displays a bar-graph history of the temporary basal rates enacted by <abbr title="With a capital L, Loop is one of several do-it-yourself artifical pancreas systems">Loop</abbr>. The display is relative to the scheduled basal rates entered in the <abbr title="With a capital L, Loop is one of several do-it-yourself artifical pancreas systems">Loop</abbr> settings. A rate displayed in this chart as +0 would indicate that no temporary basal rate was set and that the basal rate being delivered was the scheduled basal rate. Positive values indicate a temporary basal rate was set above the scheduled basal rate (i.e., more insulin delivered), and negative values indicate that a temporary basal rate was set below the scheduled basal rate (i.e., less insulin delivered).</p>
Expand All @@ -3748,7 +3748,7 @@ <h3 id="total-insulin-effect-combining-boluses-and-temporary-basal-rates">Total
<p><img alt="Loop's iob and temp basals" src="../img/insulin_delivery_iob.jpg" /></p>
<p>The insulin effect can be expressed mathematically:</p>
<div class="arithmatex">\[ \Delta BG_{I}[t] = ISF[t] \times IA[t] \]</div>
<p>where BG is the expected change in blood glucose with the units (mg/dL/5min), <abbr title="Insulin Sensitivity Factor; how many points your blood sugar will drop for each unit of insulin; sometimes called Correction Factor">ISF</abbr> is the insulin sensitivity factor (mg/dL/U) at time t, and IA is the insulin activity (U/5min) at time <em>t</em>. Insulin activity can also be thought of as a velocity or rate of change in blood glucose due to insulin. The insulin activity accounts for the EGP and any active insulin from basals and boluses.</p>
<p>where BG is the expected change in blood glucose with the units (mg/dL/5min), <abbr title="Insulin Sensitivity Factor; how many points your blood sugar will drop for each unit of insulin; sometimes called Correction Factor">ISF</abbr> is the insulin sensitivity factor (mg/dL/U) at time t, and IA is the insulin activity (U/5min) at time <em>t</em>. Insulin activity can also be thought of as a velocity or rate of change in blood glucose due to insulin. The insulin activity accounts for the <abbr title="Endogenous Glucose Production: glucose produced by the body from its reserves (mainly glycogen in the liver)">EGP</abbr> and any active insulin from basals and boluses.</p>
<h2 id="carbohydrate-effect">Carbohydrate Effect<a class="headerlink" href="#carbohydrate-effect" title="Anchor link to this Header on this Page">&para;</a></h2>
<p>Carbohydrates will raise blood glucose, but the speed and degree to which they impact blood glucose are dependent on the type of carbohydrates. High glycemic index (GI) carbohydrates will raise blood glucose quickly over a shorter time, whereas low GI foods will raise blood glucose more slowly over a longer period. Foods like candy, juice, and fruits tend to be high GI foods, while pizza, burritos, and quesadillas are usually lower GI foods. Digestion issues like gastroparesis may also contribute to variations in carbohydrate absorption.</p>
<p>Because carbohydrate absorption can be quite variable, <abbr title="With a capital L, Loop is one of several do-it-yourself artifical pancreas systems">Loop</abbr> has a model that dynamically adjusts the expected remaining time of carbohydrate absorption. To start with, <abbr title="With a capital L, Loop is one of several do-it-yourself artifical pancreas systems">Loop</abbr> allows the user to input a rough guess of how long they think the food or drink will take to absorb. The user’s guess is used as a middle of the road estimate, and <abbr title="With a capital L, Loop is one of several do-it-yourself artifical pancreas systems">Loop</abbr>’s algorithm will shorten or lengthen it based on observed blood glucose change.</p>
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