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mwittep authored Jun 25, 2024
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# TSS-Captur: A TSS-characterization pipeline for transcribed but unclassified RNA-transcripts

[![DOI](https://zenodo.org/badge/690975479.svg)](https://zenodo.org/doi/10.5281/zenodo.12527008)


The aim of this project fork was to migrate TSS-Captur to the new Nextflow DSL2 syntax while integrating new features to improve functionality and user experience. In addition to the pipeline improvements, there was a strong focus on extending accessibility through the development of a web application. NextJS was chosen for its robust features and ease of integration with server-side operations.

To enable the characterization of transcripts in an explorative manner, we have developed TSS-Captur. TSS-Captur characterizes transcripts starting on clear TSS signals obtained from TSSpredator (Herbig, 2015) that cannot be associated to any known gene. To characterize the function of the transcript, TSS-Captur integrates tools using different approaches. The following figure describes the different steps and tools run by TSS-Captur.
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- Developed by Mathias Witte Paz,
M.Sc. Bioinformatics, University of Tübingen
- Webified by Thomas Vogel,
B.Sc. Bioinformatics, University of Tübingen
B.Sc. Bioinformatics, University of Tübingen

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