BMIN503_Final_Project_Michaela_Olabisi

[msaolabisi]

This study examines the link between maternal folic acid supplementation before and during pregnancy and the risk of delivering a low birth weight (LBW) infant, defined as a birth weight below 2,500 grams.1 LBW is associated with higher neonatal morbidity and long-term health issues. Folic acid, vital for fetal development, may help prevent LBW by supporting placental health. Using data from the Pregnancy Risk Assessment Monitoring System (PRAMS), Phase 8, the study finds that folic acid supplementation during pregnancy appears to reduce LBW risk, while pre-pregnancy intake may slightly increase it. Socioeconomic factors, such as education and income, as well as race and prenatal care, also play significant roles in LBW outcomes. The study highlights the need for targeted interventions addressing these factors to reduce LBW rates. I consulted with Dr. John Holmes and Dr. Ellen Caniglia from the Department of Biostatistics, Epidemiology & Informatics. Dr. Holmes highlighted potential study limitations, such as selection bias, while Dr. Caniglia shared a relevant paper that examines the link between supplementation and adverse pregnancy outcomes like preterm birth (PTB) and LBW. You can access the final project, including all code and results, on my GitHub: https://github.com/msaolabisi/BMIN503_Final_Project.git