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gavinha authored May 24, 2024
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Expand Up @@ -13,9 +13,6 @@ ichorCNA is a tool for estimating the fraction of tumor in cell-free DNA from ul
- Clone [ichorCNA:v0.4.0](https://github.com/GavinHaLab/ichorCNA/tree/v0.4.0) or download [v0.4.0.tar.gz](https://github.com/GavinHaLab/ichorCNA/releases/tag/v0.4.0)
- To run the Snakemake pipeline, please follow instructions [here](https://github.com/broadinstitute/ichorCNA/wiki/SnakeMake-pipeline-for-ichorCNA)

## ichorCNA Wiki Page
**For more details on usage/pipelines, outputs, and FAQs, please visit the [GitHub Wiki page for ichorCNA](https://github.com/broadinstitute/ichorCNA/wiki)**

## Description
ichorCNA uses a probabilistic model, implemented as a hidden Markov model (HMM), to simultaneously segment the genome, predict large-scale copy number alterations, and estimate the tumor fraction of a ultra-low-pass whole genome sequencing sample (ULP-WGS).

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