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claudia-c-weber authored Jan 26, 2023
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This program calculates the number of distinct k-mers for each sequence record in a fasta file and divides it by the total number of k-mers in that record. Provided the number of possible distinct k-mers (4^k) is at least as large as the sequence length, this gives a measure of how diverse the k-mer composition of the sequence is. Repetitive sequences or sequences with restricted nucleotide composition, for example, will tend to have low values.

The program, which is writtern in Rust, is based on [Needletail](https://github.com/onecodex/needletail)'s efficient FASTA parser, making it efficient for large read sets.
The program, which is writtern in Rust, is based on [Needletail](https://github.com/onecodex/needletail)'s fast FASTA parser, making it efficient for large read sets.

## Usage

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