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CBFLivUni/Gene_expression_dysregulation_in_whole_blood_of_patients_with_C_difficile_infection

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Overview

This repository reproduces the R analyses from Tsakiroglou et al. 2024.

Installation

Packages used in the analyses can be installed by running install/install_r_libs.R in a fresh R session.

The package versions used for the manuscript analyses can be found within output/sessionInfo for each script.

Directions

Scripts to run the analyses from the manuscript can be found in the code folder. Outputs from each analysis are already included in this repository, so each script can be run as a standalone analysis.

To reproduce the analysis from scratch using the data files in raw, each script should be run in the order they are numbered. Raw CEL files can be obtained manually from Gene Expression Omnibus (GEO) accession no. GSE276395 and saved in raw/GSE276395_RAW, or automatically using the R script code/01_process_cel.R.

CC BY 4.0

This work is licensed under a Creative Commons Attribution 4.0 International License.

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