diff --git a/CHANGES.rst b/CHANGES.rst
index eb15658756..b486b8cb33 100644
--- a/CHANGES.rst
+++ b/CHANGES.rst
@@ -7,6 +7,13 @@ since the branch point at Zope 4.1.2.
 The change log for the previous version, Zope 4, is at
 https://github.com/zopefoundation/Zope/blob/4.x/CHANGES.rst
 
+
+5.8.5 (unreleased)
+------------------
+
+- Update to newest compatible versions of dependencies.
+
+
 5.8.4 (2023-09-06)
 ------------------
 
diff --git a/constraints.txt b/constraints.txt
index 20906077b6..c13d5b7232 100644
--- a/constraints.txt
+++ b/constraints.txt
@@ -2,8 +2,8 @@ AccessControl==6.2
 Acquisition==5.0
 AuthEncoding==5.0
 BTrees==5.0
-Chameleon==4.0.0
-DateTime==5.1
+Chameleon==4.1.0
+DateTime==5.2
 DocumentTemplate==4.4
 ExtensionClass==5.0
 MultiMapping==5.0
@@ -16,7 +16,7 @@ WSGIProxy2==0.5.1
 WebOb==1.8.7
 WebTest==3.0.0
 ZConfig==4.0
-ZODB==5.8.0
+ZODB==5.8.1
 Zope2==4.0
 beautifulsoup4==4.12.2
 cffi==1.15.1
@@ -24,14 +24,15 @@ multipart==0.2.4
 persistent==5.0
 pycparser==2.21
 python-gettext==5.0
-pytz==2023.3
+pytz==2023.3.post1
 roman==4.1
 six==1.16.0
-soupsieve==2.4.1
+soupsieve==2.4.1; python_version == '3.7'
+soupsieve==2.5; python_version > '3.7'
 transaction==3.1.0
 waitress==2.1.2
 z3c.pt==4.0
-zExceptions==4.3
+zExceptions==5.0
 zc.lockfile==3.0.post1
 zc.recipe.egg==2.0.7
 zodbpickle==3.0.1
@@ -39,7 +40,7 @@ zope.annotation==5.0
 zope.browser==3.0
 zope.browsermenu==5.0
 zope.browserpage==5.0
-zope.browserresource==5.0
+zope.browserresource==5.1
 zope.cachedescriptors==5.0
 zope.component==6.0
 zope.configuration==5.0
@@ -47,32 +48,32 @@ zope.container==5.1
 zope.contentprovider==5.0
 zope.contenttype==5.0
 zope.datetime==5.0.0
-zope.deferredimport==4.4
+zope.deferredimport==5.0
 zope.deprecation==5.0
 zope.dottedname==6.0
-zope.event==4.6
-zope.exceptions==4.6
+zope.event==5.0
+zope.exceptions==5.0.1
 zope.filerepresentation==6.0
 zope.globalrequest==2.0
 zope.hookable==5.4
-zope.i18n==5.0
+zope.i18n==5.1
 zope.i18nmessageid==6.0.1
 zope.interface==6.0
-zope.lifecycleevent==4.4
+zope.lifecycleevent==5.0
 zope.location==5.0
 zope.pagetemplate==5.0
 zope.processlifetime==3.0
 zope.proxy==5.0.0
 zope.ptresource==5.0
-zope.publisher==6.1.0
+zope.publisher==7.0
 zope.schema==7.0.1
 zope.security==6.1
 zope.sequencesort==5.0
-zope.site==4.6.1
-zope.size==4.4
+zope.site==5.0
+zope.size==5.0
 zope.structuredtext==5.0
 zope.tal==5.0.1
-zope.tales==5.2
+zope.tales==6.0
 zope.testbrowser==6.0
 zope.testing==5.0.1
 zope.traversing==5.0
diff --git a/requirements-full.txt b/requirements-full.txt
index 4545408d01..b07ab70ae4 100644
--- a/requirements-full.txt
+++ b/requirements-full.txt
@@ -1,10 +1,10 @@
-Zope==5.8.4
+-e git+https://github.com/zopefoundation/Zope.git@master#egg=Zope
 AccessControl==6.2
 Acquisition==5.0
 AuthEncoding==5.0
 BTrees==5.0
-Chameleon==4.0.0
-DateTime==5.1
+Chameleon==4.1.0
+DateTime==5.2
 DocumentTemplate==4.4
 ExtensionClass==5.0
 MultiMapping==5.0
@@ -17,7 +17,7 @@ WSGIProxy2==0.5.1
 WebOb==1.8.7
 WebTest==3.0.0
 ZConfig==4.0
-ZODB==5.8.0
+ZODB==5.8.1
 Zope2==4.0
 beautifulsoup4==4.12.2
 cffi==1.15.1
@@ -25,14 +25,15 @@ multipart==0.2.4
 persistent==5.0
 pycparser==2.21
 python-gettext==5.0
-pytz==2023.3
+pytz==2023.3.post1
 roman==4.1
 six==1.16.0
-soupsieve==2.4.1
+soupsieve==2.4.1; python_version == '3.7'
+soupsieve==2.5; python_version > '3.7'
 transaction==3.1.0
 waitress==2.1.2
 z3c.pt==4.0
-zExceptions==4.3
+zExceptions==5.0
 zc.lockfile==3.0.post1
 zc.recipe.egg==2.0.7
 zodbpickle==3.0.1
@@ -40,7 +41,7 @@ zope.annotation==5.0
 zope.browser==3.0
 zope.browsermenu==5.0
 zope.browserpage==5.0
-zope.browserresource==5.0
+zope.browserresource==5.1
 zope.cachedescriptors==5.0
 zope.component==6.0
 zope.configuration==5.0
@@ -48,32 +49,32 @@ zope.container==5.1
 zope.contentprovider==5.0
 zope.contenttype==5.0
 zope.datetime==5.0.0
-zope.deferredimport==4.4
+zope.deferredimport==5.0
 zope.deprecation==5.0
 zope.dottedname==6.0
-zope.event==4.6
-zope.exceptions==4.6
+zope.event==5.0
+zope.exceptions==5.0.1
 zope.filerepresentation==6.0
 zope.globalrequest==2.0
 zope.hookable==5.4
-zope.i18n==5.0
+zope.i18n==5.1
 zope.i18nmessageid==6.0.1
 zope.interface==6.0
-zope.lifecycleevent==4.4
+zope.lifecycleevent==5.0
 zope.location==5.0
 zope.pagetemplate==5.0
 zope.processlifetime==3.0
 zope.proxy==5.0.0
 zope.ptresource==5.0
-zope.publisher==6.1.0
+zope.publisher==7.0
 zope.schema==7.0.1
 zope.security==6.1
 zope.sequencesort==5.0
-zope.site==4.6.1
-zope.size==4.4
+zope.site==5.0
+zope.size==5.0
 zope.structuredtext==5.0
 zope.tal==5.0.1
-zope.tales==5.2
+zope.tales==6.0
 zope.testbrowser==6.0
 zope.testing==5.0.1
 zope.traversing==5.0
diff --git a/setup.py b/setup.py
index acbf15a607..d80b72e718 100644
--- a/setup.py
+++ b/setup.py
@@ -29,7 +29,7 @@ def _read_file(filename):
 README = _read_file('README.rst')
 CHANGES = _read_file('CHANGES.rst')
 
-version = '5.8.4'
+version = '5.8.5.dev0'
 
 setup(
     name='Zope',
diff --git a/versions-prod.cfg b/versions-prod.cfg
index f7655170af..ab183a9f6b 100644
--- a/versions-prod.cfg
+++ b/versions-prod.cfg
@@ -2,14 +2,14 @@
 # Version pins for required and commonly used dependencies.
 
 [versions]
-Zope = 5.8.4
+Zope =
 Zope2 = 4.0
 AccessControl = 6.2
 Acquisition = 5.0
 AuthEncoding = 5.0
 BTrees = 5.0
-Chameleon = 4.0.0
-DateTime = 5.1
+Chameleon = 4.1.0
+DateTime = 5.2
 DocumentTemplate = 4.4
 ExtensionClass = 5.0
 MultiMapping = 5.0
@@ -21,21 +21,21 @@ WebTest = 3.0.0
 WSGIProxy2 = 0.5.1
 WebOb = 1.8.7
 ZConfig = 4.0
-ZODB = 5.8.0
+ZODB = 5.8.1
 beautifulsoup4 = 4.12.2
 cffi = 1.15.1
 multipart = 0.2.4
 persistent = 5.0
 pycparser = 2.21
 python-gettext = 5.0
-pytz = 2023.3
+pytz = 2023.3.post1
 six = 1.16.0
 roman = 4.1
-soupsieve = 2.4.1
+soupsieve = 2.5
 transaction = 3.1.0
 waitress = 2.1.2
 z3c.pt = 4.0
-zExceptions = 4.3
+zExceptions = 5.0
 zc.lockfile = 3.0.post1
 zc.recipe.egg = 2.0.7
 zodbpickle = 3.0.1
@@ -43,7 +43,7 @@ zope.annotation = 5.0
 zope.browser = 3.0
 zope.browsermenu = 5.0
 zope.browserpage = 5.0
-zope.browserresource = 5.0
+zope.browserresource = 5.1
 zope.cachedescriptors = 5.0
 zope.component = 6.0
 zope.configuration = 5.0
@@ -51,32 +51,32 @@ zope.container = 5.1
 zope.contentprovider = 5.0
 zope.contenttype = 5.0
 zope.datetime = 5.0.0
-zope.deferredimport = 4.4
+zope.deferredimport = 5.0
 zope.deprecation = 5.0
 zope.dottedname = 6.0
-zope.event = 4.6
-zope.exceptions = 4.6
+zope.event = 5.0
+zope.exceptions = 5.0.1
 zope.filerepresentation = 6.0
 zope.globalrequest = 2.0
 zope.hookable = 5.4
-zope.i18n = 5.0
+zope.i18n = 5.1
 zope.i18nmessageid = 6.0.1
 zope.interface = 6.0
-zope.lifecycleevent = 4.4
+zope.lifecycleevent = 5.0
 zope.location = 5.0
 zope.pagetemplate = 5.0
 zope.processlifetime = 3.0
 zope.proxy = 5.0.0
 zope.ptresource = 5.0
-zope.publisher = 6.1.0
+zope.publisher = 7.0
 zope.schema = 7.0.1
 zope.security = 6.1
 zope.sequencesort = 5.0
-zope.site = 4.6.1
-zope.size = 4.4
+zope.site = 5.0
+zope.size = 5.0
 zope.structuredtext = 5.0
 zope.tal = 5.0.1
-zope.tales = 5.2
+zope.tales = 6.0
 zope.testbrowser = 6.0
 zope.testing = 5.0.1
 zope.traversing = 5.0
@@ -85,6 +85,8 @@ zope.viewlet = 5.0
 [versions:python37]
 # PasteDeploy 3.x works on Python 3.7 but pulls tons of dependencies
 PasteDeploy = 2.1.1
+# SoupSieve 2.5 and up requires Python 3.8
+soupsieve = 2.4.1
 
 [versions:python312]
 # Use the development version here until the final release to test Products
diff --git a/versions.cfg b/versions.cfg
index c1db38aba0..762c88ba42 100644
--- a/versions.cfg
+++ b/versions.cfg
@@ -7,39 +7,39 @@ versions = versions
 # Version pins for development and optional dependencies.
 Babel = 2.12.1
 Jinja2 = 3.1.2
-Missing = 4.2
+Missing = 5.0
 MarkupSafe = 2.1.3
 Products.BTreeFolder2 = 5.1
 Products.ZCatalog = 7.0
-Pygments = 2.15.1
+Pygments = 2.16.1
 Record = 4.0
-# sphinx-rtd-theme 1.2.2 requires Sphinx<7
-Sphinx = 6.2.1
+Sphinx = 7.2.5
 alabaster = 0.7.13
-certifi = 2023.5.7
-charset-normalizer = 3.1.0
+certifi = 2023.7.22
+charset-normalizer = 3.2.0
 collective.recipe.template = 2.2
-# sphinx-rtd-theme 1.2.2 requires docutils<19
+# sphinx-rtd-theme 1.3.0 requires docutils<19
 docutils = 0.18.1
 five.localsitemanager = 4.0
 idna = 3.4
 imagesize = 1.4.1
-importlib-metadata = 5.1.0
+# XXX importlib-metadata 6.8.0 requires Python 3.8
+importlib-metadata = 6.8.0
 mr.developer = 2.0.1
 packaging = 23.1
 plone.recipe.command = 1.1
 requests = 2.31.0
 snowballstemmer = 2.2.0
-sphinx-rtd-theme = 1.2.2
-sphinxcontrib-applehelp = 1.0.4
-sphinxcontrib-devhelp = 1.0.2
-sphinxcontrib-htmlhelp = 2.0.1
+sphinx-rtd-theme = 1.3.0
+sphinxcontrib-applehelp = 1.0.7
+sphinxcontrib-devhelp = 1.0.5
+sphinxcontrib-htmlhelp = 2.0.4
 sphinxcontrib-jquery = 4.1
 sphinxcontrib-jsmath = 1.0.1
-sphinxcontrib-qthelp = 1.0.3
-sphinxcontrib-serializinghtml = 1.1.5
+sphinxcontrib-qthelp = 1.0.6
+sphinxcontrib-serializinghtml = 1.1.9
 tempstorage = 6.0
-urllib3 = 2.0.3
+urllib3 = 2.0.4
 z3c.checkversions = 2.1
 zc.recipe.testrunner = 3.0
 zipp = 3.16.2