diff --git a/testing/tests/api/conftest.py b/testing/tests/api/conftest.py
new file mode 100644
index 000000000..d4ba7f618
--- /dev/null
+++ b/testing/tests/api/conftest.py
@@ -0,0 +1,9 @@
+import pytest
+
+from pymol import cmd
+
+
+@pytest.fixture(autouse=True)
+def setup():
+    cmd.reinitialize()
+    yield