Association example wrong

[cannin]

Spec L1 V1.3. In figure 2.37 the example are explicatory text are wrong. An association should only result in a multimer or complex. In the example given a process node should have been used to describe the aggregation of heme (or should that be haem) and globin to form the haemoglobin macromolecule. I propose we either remove the example or modify it to show the usage above.

Reported by: stumoodie

[cannin]

It is a fossil from the time before we restricted the output of an association to complex. I agree that the figure should be changed so that either:

1. the first association is turned into a process, to show that an association cannot be used if the output is not a complex or a multimer
2. the macromolecule is changed to a complex and the macromolecule multimer into a complex multimer.
   The text should be changed accordingly.

Regarding the spelling, it is either hemoglobin or h\ae{moglobin} but not haemoglobin.

Original comment by: lenov

[adrienrougny]

Still there in V2.0.

[hasanbalci]

@cannin In which direction should we move forward in this issue?

[hasanbalci]

Further discussion with editors: to be able to make this change we need to address complex and definition of association.

[adrienrougny]

Discussions at COMBINE: split the example in two:

• hemoglobin (subunit->macromolecule)
• p53 (subunit->multimer) (bonus: find an example where the subunit and multimer names are different: look into myosin II or dihydropyrimidase)

[adrienrougny]

[adrienrougny]

The examples above are now in the spec (p30-31), they should be checked, and the issue can be closed.