diff --git a/ocs_ci/deployment/deployment.py b/ocs_ci/deployment/deployment.py
index b1914145aec..cbb81e7865d 100644
--- a/ocs_ci/deployment/deployment.py
+++ b/ocs_ci/deployment/deployment.py
@@ -374,6 +374,12 @@ def post_ocp_deploy(self):
             enable_huge_pages()
         if config.DEPLOYMENT.get("dummy_zone_node_labels"):
             create_dummy_zone_labels()
+        ibmcloud_ipi = (
+            config.ENV_DATA["platform"] == constants.IBMCLOUD_PLATFORM
+            and config.ENV_DATA["deployment_type"] == "ipi"
+        )
+        if ibmcloud_ipi:
+            ibmcloud.label_nodes_region()
 
     def label_and_taint_nodes(self):
         """
@@ -692,6 +698,7 @@ def deploy_ocs_via_operator(self, image=None):
             ibmcloud.add_deployment_dependencies()
             if not live_deployment:
                 create_ocs_secret(self.namespace)
+        if config.ENV_DATA["platform"] == constants.IBMCLOUD_PLATFORM:
             if config.DEPLOYMENT.get("create_ibm_cos_secret", True):
                 logger.info("Creating secret for IBM Cloud Object Storage")
                 with open(constants.IBM_COS_SECRET_YAML, "r") as cos_secret_fd:
diff --git a/ocs_ci/utility/ibmcloud.py b/ocs_ci/utility/ibmcloud.py
index 3bf12d11d85..62a2e5f7685 100644
--- a/ocs_ci/utility/ibmcloud.py
+++ b/ocs_ci/utility/ibmcloud.py
@@ -518,3 +518,16 @@ def delete_volume_id(self, volume):
             logger.info(f"volume is deleted successfully: {volume}")
         else:
             logger.info("volume is not deleted")
+
+
+def label_nodes_region():
+    """
+    Apply the region label to the worker nodes.
+    Necessary for IBM COS-backed backingstore support.
+
+    """
+    logger.info("Applying region label to worker nodes")
+    region = config.ENV_DATA.get("region")
+    worker_nodes = get_nodes(node_type=constants.WORKER_MACHINE)
+    for node in worker_nodes:
+        node.add_label(rf"ibm-cloud\.kubernetes\.io/region={region}")