diff --git a/setup.py b/setup.py
index 28979857b36..f80828d66df 100644
--- a/setup.py
+++ b/setup.py
@@ -17,7 +17,7 @@
     python_requires=">=3.9.18",
     install_requires=[
         "apache-libcloud==3.1.0",
-        "cryptography==42.0.4",
+        "cryptography==43.0.1",
         "docopt==0.6.2",
         "gevent==23.9.1",
         "reportportal-client==3.2.3",
@@ -77,7 +77,7 @@
         "junitparser==3.1.0",
         "flaky==3.7.0",
         "ocp-network-split",
-        "pyopenssl==24.0.0",
+        "pyopenssl==24.2.1",
         "pyparsing==2.4.7",
         "mysql-connector-python==8.0.27",
         "pytest-repeat==0.9.3",