diff --git a/open_prime_rando/dynamic_schema.py b/open_prime_rando/dynamic_schema.py
new file mode 100644
index 0000000..782d9df
--- /dev/null
+++ b/open_prime_rando/dynamic_schema.py
@@ -0,0 +1,33 @@
+import copy
+
+from open_prime_rando.patcher_editor import PatcherEditor
+import open_prime_rando.echoes.asset_ids.world
+
+
+def expand_schema(base_schema: dict, editor: PatcherEditor) -> dict:
+    schema = copy.deepcopy(base_schema)
+
+    world_props = schema["properties"]["worlds"]["properties"] = {}
+    for world, mlvl_id in open_prime_rando.echoes.asset_ids.world.NAME_TO_ID.items():
+        world_def = copy.deepcopy(schema["$defs"]["world"])
+        world_props[world] = world_def
+
+        mlvl = editor.get_mlvl(mlvl_id)
+        area_props = {}
+        world_def["properties"]["areas"] = {"type": "object", "additionalProperties": False, "properties": area_props}
+
+        for area in mlvl.areas:
+            area_def = copy.deepcopy(schema["$defs"]["area"])
+            area_props[area.name] = area_def
+
+            area_def["properties"]["layers"] = {
+                "type": "object",
+                "properties": {
+                    layer.name: {"type": "boolean"}
+                    for layer in area.layers
+                },
+                "default": {},
+                "additionalProperties": False,
+            }
+
+    return schema
diff --git a/open_prime_rando/echoes/schema.json b/open_prime_rando/echoes/schema.json
index e29c563..420d77d 100644
--- a/open_prime_rando/echoes/schema.json
+++ b/open_prime_rando/echoes/schema.json
@@ -6,6 +6,19 @@
             "type": "string",
             "format": "uri"
         },
+        "worlds": {
+            "type": "object",
+            "properties": {
+                "Great Temple": { "$ref": "#/$defs/world" },
+                "Temple Grounds": { "$ref": "#/$defs/world" },
+                "Agon Wastes": { "$ref": "#/$defs/world" },
+                "Torvus Bog": { "$ref": "#/$defs/world" },
+                "Sanctuary Fortress": { "$ref": "#/$defs/world" }
+            },
+            "default": {},
+            "additionalProperties": false,
+            "$comment": "The list of properties is replaced in runtime with all worlds in the provided ISO."
+        },
         "small_randomizations": {
             "properties": {
                 "seed": {
@@ -44,5 +57,37 @@
     ],
     "additionalProperties": false,
     "$defs": {
+        "world": {
+            "type": "object",
+            "properties": {
+                "areas": {
+                    "type": "object",
+                    "patternProperties": {
+                        ".*": {
+                            "$ref": "#/$defs/area"
+                        }
+                    }
+                }
+            },
+            "required": ["areas"],
+            "additionalProperties": false,
+            "$comment": "The list of areas is replaced in runtime with the existing areas of each specific world."
+        },
+        "area": {
+            "type": "object",
+            "properties": {
+                "layers": {
+                    "type": "object",
+                    "patternProperties": {
+                        ".*": {
+                            "type": "boolean"
+                        }
+                    },
+                    "default": {},
+                    "$comment": "The list of layers is replaced in runtime with the existing layers of each specific area."
+                }
+            },
+            "additionalProperties": false
+        }
     }
 }
diff --git a/open_prime_rando/echoes_patcher.py b/open_prime_rando/echoes_patcher.py
index 881e2de..8594fc1 100644
--- a/open_prime_rando/echoes_patcher.py
+++ b/open_prime_rando/echoes_patcher.py
@@ -4,10 +4,12 @@
 
 from retro_data_structures.asset_manager import FileProvider
 
+from open_prime_rando import dynamic_schema
 from open_prime_rando.echoes.inverted import apply_inverted
 from open_prime_rando.echoes.small_randomizations import apply_small_randomizations
 from open_prime_rando.patcher_editor import PatcherEditor
 from open_prime_rando.validator_with_default import DefaultValidatingDraft7Validator
+import open_prime_rando.echoes.asset_ids.world
 
 LOG = logging.getLogger("echoes_patcher")
 
@@ -17,15 +19,35 @@ def _read_schema():
         return json.load(f)
 
 
+def apply_area_modifications(editor: PatcherEditor, configuration: dict[str, dict]):
+    for world_name, world_config in configuration.items():
+        mlvl = editor.get_mlvl(open_prime_rando.echoes.asset_ids.world.NAME_TO_ID[world_name])
+
+        for area in mlvl.areas:
+            area_name = area.name
+            if area_name not in world_config["areas"]:
+                continue
+
+            area_config = world_config["areas"][area_name]
+            for layer_name, layer_state in area_config["layers"].items():
+                LOG.debug("Setting layer %s of %s - %s to %s", layer_name, world_name, area_name, str(layer_state))
+                area.get_layer(layer_name).active = layer_state
+
+
 def patch_paks(file_provider: FileProvider, output_path: Path, configuration: dict):
     LOG.info("Will patch files at %s", file_provider)
 
-    DefaultValidatingDraft7Validator(_read_schema()).validate(configuration)
-
     editor = PatcherEditor(file_provider)
 
+    LOG.info("Preparing schema")
+    schema = dynamic_schema.expand_schema(_read_schema(), editor)
+
+    LOG.info("Validating schema")
+    DefaultValidatingDraft7Validator(schema).validate(configuration)
+
     # custom_assets.create_custom_assets(editor)
     # specific_patches(editor)
+    apply_area_modifications(editor, configuration["worlds"])
     apply_small_randomizations(editor, configuration["small_randomizations"])
     # apply_door_rando(editor, [])