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ddpheno.obo
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format-version: 1.2
data-version: ddpheno/releases/2019-04-12
ontology: ddpheno.obo
property_value: http://purl.org/dc/elements/1.1/description "Ontology about the phenotypes observed in Dicty" xsd:string
property_value: http://purl.org/dc/elements/1.1/title "Dicty Phenotype Ontology" xsd:string
property_value: http://purl.org/dc/terms/license "CC-BY" xsd:string
[Term]
id: BFO:0000001
name: entity
property_value: BFO:0000179 "entity" xsd:string
property_value: BFO:0000180 "Entity" xsd:string
property_value: IAO:0000112 "Julius Caesar" xsd:string
property_value: IAO:0000112 "the Second World War" xsd:string
property_value: IAO:0000112 "Verdi’s Requiem" xsd:string
property_value: IAO:0000112 "your body mass index" xsd:string
property_value: IAO:0000116 "BFO 2 Reference: In all areas of empirical inquiry we encounter general terms of two sorts. First are general terms which refer to universals or types:animaltuberculosissurgical procedurediseaseSecond, are general terms used to refer to groups of entities which instantiate a given universal but do not correspond to the extension of any subuniversal of that universal because there is nothing intrinsic to the entities in question by virtue of which they – and only they – are counted as belonging to the given group. Examples are: animal purchased by the Emperortuberculosis diagnosed on a Wednesdaysurgical procedure performed on a patient from Stockholmperson identified as candidate for clinical trial #2056-555person who is signatory of Form 656-PPVpainting by Leonardo da VinciSuch terms, which represent what are called ‘specializations’ in [81" xsd:string
property_value: IAO:0000116 "Entity doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. For example Werner Ceusters 'portions of reality' include 4 sorts, entities (as BFO construes them), universals, configurations, and relations. It is an open question as to whether entities as construed in BFO will at some point also include these other portions of reality. See, for example, 'How to track absolutely everything' at http://www.referent-tracking.com/_RTU/papers/CeustersICbookRevised.pdf" xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/0000004", comment="per discussion with Barry Smith", http://www.w3.org/2000/01/rdf-schema#seeAlso="http://www.referent-tracking.com/_RTU/papers/CeustersICbookRevised.pdf"}
property_value: IAO:0000600 "An entity is anything that exists or has existed or will exist. (axiom label in BFO2 Reference: [001-001])" xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/001-001"}
property_value: isDefinedBy http://purl.obolibrary.org/obo/bfo.owl
[Term]
id: BFO:0000002
name: continuant
def: "An entity that exists in full at any time in which it exists at all, persists through time while maintaining its identity and has no temporal parts." []
is_a: BFO:0000001 ! entity
disjoint_from: BFO:0000003 ! occurrent
relationship: part_of BFO:0000002 ! continuant
property_value: BFO:0000179 "continuant" xsd:string
property_value: BFO:0000180 "Continuant" xsd:string
property_value: IAO:0000116 "BFO 2 Reference: Continuant entities are entities which can be sliced to yield parts only along the spatial dimension, yielding for example the parts of your table which we call its legs, its top, its nails. ‘My desk stretches from the window to the door. It has spatial parts, and can be sliced (in space) in two. With respect to time, however, a thing is a continuant.’ [60, p. 240" xsd:string
property_value: IAO:0000116 "Continuant doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. For example, in an expansion involving bringing in some of Ceuster's other portions of reality, questions are raised as to whether universals are continuants" xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/0000007"}
property_value: IAO:0000600 "A continuant is an entity that persists, endures, or continues to exist through time while maintaining its identity. (axiom label in BFO2 Reference: [008-002])" xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/008-002"}
property_value: IAO:0000601 "if b is a continuant and if, for some t, c has_continuant_part b at t, then c is a continuant. (axiom label in BFO2 Reference: [126-001])" xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/126-001"}
property_value: IAO:0000601 "if b is a continuant and if, for some t, cis continuant_part of b at t, then c is a continuant. (axiom label in BFO2 Reference: [009-002])" xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/009-002"}
property_value: IAO:0000601 "if b is a material entity, then there is some temporal interval (referred to below as a one-dimensional temporal region) during which b exists. (axiom label in BFO2 Reference: [011-002])" xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/011-002"}
property_value: IAO:0000602 "(forall (x y) (if (and (Continuant x) (exists (t) (continuantPartOfAt y x t))) (Continuant y))) // axiom label in BFO2 CLIF: [009-002] " xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/009-002"}
property_value: IAO:0000602 "(forall (x y) (if (and (Continuant x) (exists (t) (hasContinuantPartOfAt y x t))) (Continuant y))) // axiom label in BFO2 CLIF: [126-001] " xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/126-001"}
property_value: IAO:0000602 "(forall (x) (if (Continuant x) (Entity x))) // axiom label in BFO2 CLIF: [008-002] " xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/008-002"}
property_value: IAO:0000602 "(forall (x) (if (Material Entity x) (exists (t) (and (TemporalRegion t) (existsAt x t))))) // axiom label in BFO2 CLIF: [011-002] " xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/011-002"}
property_value: isDefinedBy http://purl.obolibrary.org/obo/bfo.owl
[Term]
id: BFO:0000003
name: occurrent
def: "An entity that has temporal parts and that happens, unfolds or develops through time." []
is_a: BFO:0000001 ! entity
relationship: part_of BFO:0000003 ! occurrent
property_value: BFO:0000179 "occurrent" xsd:string
property_value: BFO:0000180 "Occurrent" xsd:string
property_value: IAO:0000116 "BFO 2 Reference: every occurrent that is not a temporal or spatiotemporal region is s-dependent on some independent continuant that is not a spatial region" xsd:string
property_value: IAO:0000116 "BFO 2 Reference: s-dependence obtains between every process and its participants in the sense that, as a matter of necessity, this process could not have existed unless these or those participants existed also. A process may have a succession of participants at different phases of its unfolding. Thus there may be different players on the field at different times during the course of a football game; but the process which is the entire game s-depends_on all of these players nonetheless. Some temporal parts of this process will s-depend_on on only some of the players." xsd:string
property_value: IAO:0000116 "Occurrent doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. An example would be the sum of a process and the process boundary of another process." xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/0000006", comment="per discussion with Barry Smith"}
property_value: IAO:0000116 "Simons uses different terminology for relations of occurrents to regions: Denote the spatio-temporal location of a given occurrent e by 'spn[e]' and call this region its span. We may say an occurrent is at its span, in any larger region, and covers any smaller region. Now suppose we have fixed a frame of reference so that we can speak not merely of spatio-temporal but also of spatial regions (places) and temporal regions (times). The spread of an occurrent, (relative to a frame of reference) is the space it exactly occupies, and its spell is likewise the time it exactly occupies. We write 'spr[e]' and `spl[e]' respectively for the spread and spell of e, omitting mention of the frame." xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/0000012"}
property_value: IAO:0000600 "An occurrent is an entity that unfolds itself in time or it is the instantaneous boundary of such an entity (for example a beginning or an ending) or it is a temporal or spatiotemporal region which such an entity occupies_temporal_region or occupies_spatiotemporal_region. (axiom label in BFO2 Reference: [077-002])" xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/077-002"}
property_value: IAO:0000601 "b is an occurrent entity iff b is an entity that has temporal parts. (axiom label in BFO2 Reference: [079-001])" xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/079-001"}
property_value: IAO:0000601 "Every occurrent occupies_spatiotemporal_region some spatiotemporal region. (axiom label in BFO2 Reference: [108-001])" xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/108-001"}
property_value: IAO:0000602 "(forall (x) (if (Occurrent x) (exists (r) (and (SpatioTemporalRegion r) (occupiesSpatioTemporalRegion x r))))) // axiom label in BFO2 CLIF: [108-001] " xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/108-001"}
property_value: IAO:0000602 "(forall (x) (iff (Occurrent x) (and (Entity x) (exists (y) (temporalPartOf y x))))) // axiom label in BFO2 CLIF: [079-001] " xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/079-001"}
property_value: isDefinedBy http://purl.obolibrary.org/obo/bfo.owl
[Term]
id: BFO:0000004
name: independent continuant
def: "A continuant that is a bearer of quality and realizable entity entities, in which other entities inhere and which itself cannot inhere in anything." []
def: "b is an independent continuant = Def. b is a continuant which is such that there is no c and no t such that b s-depends_on c at t. (axiom label in BFO2 Reference: [017-002])" [] {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/017-002"}
is_a: BFO:0000002 ! continuant
disjoint_from: BFO:0000020 ! specifically dependent continuant
disjoint_from: BFO:0000031 ! generically dependent continuant
relationship: part_of BFO:0000004 ! independent continuant
property_value: BFO:0000179 "ic" xsd:string
property_value: BFO:0000180 "IndependentContinuant" xsd:string
property_value: IAO:0000112 "a chair" xsd:string
property_value: IAO:0000112 "a heart" xsd:string
property_value: IAO:0000112 "a leg" xsd:string
property_value: IAO:0000112 "a molecule" xsd:string
property_value: IAO:0000112 "a spatial region" xsd:string
property_value: IAO:0000112 "an atom" xsd:string
property_value: IAO:0000112 "an orchestra." xsd:string
property_value: IAO:0000112 "an organism" xsd:string
property_value: IAO:0000112 "the bottom right portion of a human torso" xsd:string
property_value: IAO:0000112 "the interior of your mouth" xsd:string
property_value: IAO:0000601 "For any independent continuant b and any time t there is some spatial region r such that b is located_in r at t. (axiom label in BFO2 Reference: [134-001])" xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/134-001"}
property_value: IAO:0000601 "For every independent continuant b and time t during the region of time spanned by its life, there are entities which s-depends_on b during t. (axiom label in BFO2 Reference: [018-002])" xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/018-002"}
property_value: IAO:0000602 "(forall (x t) (if (and (IndependentContinuant x) (existsAt x t)) (exists (y) (and (Entity y) (specificallyDependsOnAt y x t))))) // axiom label in BFO2 CLIF: [018-002] " xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/018-002"}
property_value: IAO:0000602 "(forall (x t) (if (IndependentContinuant x) (exists (r) (and (SpatialRegion r) (locatedInAt x r t))))) // axiom label in BFO2 CLIF: [134-001] " xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/134-001"}
property_value: IAO:0000602 "(iff (IndependentContinuant a) (and (Continuant a) (not (exists (b t) (specificallyDependsOnAt a b t))))) // axiom label in BFO2 CLIF: [017-002] " xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/017-002"}
property_value: isDefinedBy http://purl.obolibrary.org/obo/bfo.owl
[Term]
id: BFO:0000015
name: process
def: "An occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t." []
def: "p is a process = Def. p is an occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t. (axiom label in BFO2 Reference: [083-003])" [] {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/083-003"}
is_a: BFO:0000003 ! occurrent
property_value: BFO:0000179 "process" xsd:string
property_value: BFO:0000180 "Process" xsd:string
property_value: IAO:0000112 "a process of cell-division, \\ a beating of the heart" xsd:string
property_value: IAO:0000112 "a process of meiosis" xsd:string
property_value: IAO:0000112 "a process of sleeping" xsd:string
property_value: IAO:0000112 "the course of a disease" xsd:string
property_value: IAO:0000112 "the flight of a bird" xsd:string
property_value: IAO:0000112 "the life of an organism" xsd:string
property_value: IAO:0000112 "your process of aging." xsd:string
property_value: IAO:0000116 "BFO 2 Reference: The realm of occurrents is less pervasively marked by the presence of natural units than is the case in the realm of independent continuants. Thus there is here no counterpart of ‘object’. In BFO 1.0 ‘process’ served as such a counterpart. In BFO 2.0 ‘process’ is, rather, the occurrent counterpart of ‘material entity’. Those natural – as contrasted with engineered, which here means: deliberately executed – units which do exist in the realm of occurrents are typically either parasitic on the existence of natural units on the continuant side, or they are fiat in nature. Thus we can count lives; we can count football games; we can count chemical reactions performed in experiments or in chemical manufacturing. We cannot count the processes taking place, for instance, in an episode of insect mating behavior.Even where natural units are identifiable, for example cycles in a cyclical process such as the beating of a heart or an organism’s sleep/wake cycle, the processes in question form a sequence with no discontinuities (temporal gaps) of the sort that we find for instance where billiard balls or zebrafish or planets are separated by clear spatial gaps. Lives of organisms are process units, but they too unfold in a continuous series from other, prior processes such as fertilization, and they unfold in turn in continuous series of post-life processes such as post-mortem decay. Clear examples of boundaries of processes are almost always of the fiat sort (midnight, a time of death as declared in an operating theater or on a death certificate, the initiation of a state of war)" xsd:string
property_value: IAO:0000602 "(iff (Process a) (and (Occurrent a) (exists (b) (properTemporalPartOf b a)) (exists (c t) (and (MaterialEntity c) (specificallyDependsOnAt a c t))))) // axiom label in BFO2 CLIF: [083-003] " xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/083-003"}
property_value: isDefinedBy http://purl.obolibrary.org/obo/bfo.owl
[Term]
id: BFO:0000017
name: realizable entity
def: "A specifically dependent continuant that inheres in continuant entities and are not exhibited in full at every time in which it inheres in an entity or group of entities. The exhibition or actualization of a realizable entity is a particular manifestation, functioning or process that occurs under certain circumstances." []
is_a: BFO:0000020 ! specifically dependent continuant
disjoint_from: BFO:0000019 ! quality
relationship: part_of BFO:0000017 ! realizable entity
property_value: BFO:0000179 "realizable" xsd:string
property_value: BFO:0000180 "RealizableEntity" xsd:string
property_value: IAO:0000112 "the disposition of this piece of metal to conduct electricity." xsd:string
property_value: IAO:0000112 "the disposition of your blood to coagulate" xsd:string
property_value: IAO:0000112 "the function of your reproductive organs" xsd:string
property_value: IAO:0000112 "the role of being a doctor" xsd:string
property_value: IAO:0000112 "the role of this boundary to delineate where Utah and Colorado meet" xsd:string
property_value: IAO:0000600 "To say that b is a realizable entity is to say that b is a specifically dependent continuant that inheres in some independent continuant which is not a spatial region and is of a type instances of which are realized in processes of a correlated type. (axiom label in BFO2 Reference: [058-002])" xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/058-002"}
property_value: IAO:0000601 "All realizable dependent continuants have independent continuants that are not spatial regions as their bearers. (axiom label in BFO2 Reference: [060-002])" xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/060-002"}
property_value: IAO:0000602 "(forall (x t) (if (RealizableEntity x) (exists (y) (and (IndependentContinuant y) (not (SpatialRegion y)) (bearerOfAt y x t))))) // axiom label in BFO2 CLIF: [060-002] " xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/060-002"}
property_value: IAO:0000602 "(forall (x) (if (RealizableEntity x) (and (SpecificallyDependentContinuant x) (exists (y) (and (IndependentContinuant y) (not (SpatialRegion y)) (inheresIn x y)))))) // axiom label in BFO2 CLIF: [058-002] " xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/058-002"}
property_value: isDefinedBy http://purl.obolibrary.org/obo/bfo.owl
[Term]
id: BFO:0000019
name: quality
is_a: BFO:0000020 ! specifically dependent continuant
relationship: part_of BFO:0000019 ! quality
property_value: BFO:0000179 "quality" xsd:string
property_value: BFO:0000180 "Quality" xsd:string
property_value: IAO:0000112 "the ambient temperature of this portion of air" xsd:string
property_value: IAO:0000112 "the color of a tomato" xsd:string
property_value: IAO:0000112 "the length of the circumference of your waist" xsd:string
property_value: IAO:0000112 "the mass of this piece of gold." xsd:string
property_value: IAO:0000112 "the shape of your nose" xsd:string
property_value: IAO:0000112 "the shape of your nostril" xsd:string
property_value: IAO:0000600 "a quality is a specifically dependent continuant that, in contrast to roles and dispositions, does not require any further process in order to be realized. (axiom label in BFO2 Reference: [055-001])" xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/055-001"}
property_value: IAO:0000601 "If an entity is a quality at any time that it exists, then it is a quality at every time that it exists. (axiom label in BFO2 Reference: [105-001])" xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/105-001"}
property_value: IAO:0000602 "(forall (x) (if (exists (t) (and (existsAt x t) (Quality x))) (forall (t_1) (if (existsAt x t_1) (Quality x))))) // axiom label in BFO2 CLIF: [105-001] " xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/105-001"}
property_value: IAO:0000602 "(forall (x) (if (Quality x) (SpecificallyDependentContinuant x))) // axiom label in BFO2 CLIF: [055-001] " xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/055-001"}
property_value: isDefinedBy http://purl.obolibrary.org/obo/bfo.owl
[Term]
id: BFO:0000020
name: specifically dependent continuant
def: "A continuant that inheres in or is borne by other entities. Every instance of A requires some specific instance of B which must always be the same." []
def: "b is a specifically dependent continuant = Def. b is a continuant & there is some independent continuant c which is not a spatial region and which is such that b s-depends_on c at every time t during the course of b’s existence. (axiom label in BFO2 Reference: [050-003])" [] {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/050-003"}
is_a: BFO:0000002 ! continuant
disjoint_from: BFO:0000031 ! generically dependent continuant
relationship: part_of BFO:0000020 ! specifically dependent continuant
property_value: BFO:0000179 "sdc" xsd:string
property_value: BFO:0000180 "SpecificallyDependentContinuant" xsd:string
property_value: IAO:0000112 "of one-sided specifically dependent continuants: the mass of this tomato" xsd:string
property_value: IAO:0000112 "of relational dependent continuants (multiple bearers): John’s love for Mary, the ownership relation between John and this statue, the relation of authority between John and his subordinates." xsd:string
property_value: IAO:0000112 "Reciprocal specifically dependent continuants: the function of this key to open this lock and the mutually dependent disposition of this lock: to be opened by this key" xsd:string
property_value: IAO:0000112 "the disposition of this fish to decay" xsd:string
property_value: IAO:0000112 "the function of this heart: to pump blood" xsd:string
property_value: IAO:0000112 "the mutual dependence of proton donors and acceptors in chemical reactions [79" xsd:string
property_value: IAO:0000112 "the mutual dependence of the role predator and the role prey as played by two organisms in a given interaction" xsd:string
property_value: IAO:0000112 "the pink color of a medium rare piece of grilled filet mignon at its center" xsd:string
property_value: IAO:0000112 "the role of being a doctor" xsd:string
property_value: IAO:0000112 "the shape of this hole." xsd:string
property_value: IAO:0000112 "the smell of this portion of mozzarella" xsd:string
property_value: IAO:0000116 "Specifically dependent continuant doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. We're not sure what else will develop here, but for example there are questions such as what are promises, obligation, etc." xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/0000005", comment="per discussion with Barry Smith"}
property_value: IAO:0000602 "(iff (SpecificallyDependentContinuant a) (and (Continuant a) (forall (t) (if (existsAt a t) (exists (b) (and (IndependentContinuant b) (not (SpatialRegion b)) (specificallyDependsOnAt a b t))))))) // axiom label in BFO2 CLIF: [050-003] " xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/050-003"}
property_value: isDefinedBy http://purl.obolibrary.org/obo/bfo.owl
[Term]
id: BFO:0000031
name: generically dependent continuant
def: "A continuant that is dependent on one or other independent continuant bearers. For every instance of A requires some instance of (an independent continuant type) B but which instance of B serves can change from time to time." []
def: "b is a generically dependent continuant = Def. b is a continuant that g-depends_on one or more other entities. (axiom label in BFO2 Reference: [074-001])" [] {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/074-001"}
is_a: BFO:0000002 ! continuant
relationship: part_of BFO:0000031 ! generically dependent continuant
property_value: BFO:0000179 "gdc" xsd:string
property_value: BFO:0000180 "GenericallyDependentContinuant" xsd:string
property_value: IAO:0000112 "The entries in your database are patterns instantiated as quality instances in your hard drive. The database itself is an aggregate of such patterns. When you create the database you create a particular instance of the generically dependent continuant type database. Each entry in the database is an instance of the generically dependent continuant type IAO: information content entity." xsd:string
property_value: IAO:0000112 "the pdf file on your laptop, the pdf file that is a copy thereof on my laptop" xsd:string
property_value: IAO:0000112 "the sequence of this protein molecule; the sequence that is a copy thereof in that protein molecule." xsd:string
property_value: IAO:0000602 "(iff (GenericallyDependentContinuant a) (and (Continuant a) (exists (b t) (genericallyDependsOnAt a b t)))) // axiom label in BFO2 CLIF: [074-001] " xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/074-001"}
property_value: isDefinedBy http://purl.obolibrary.org/obo/bfo.owl
[Term]
id: BFO:0000040
name: material entity
def: "An independent continuant that is spatially extended whose identity is independent of that of other entities and can be maintained through time." []
is_a: BFO:0000004 ! independent continuant
property_value: BFO:0000179 "material" xsd:string
property_value: BFO:0000180 "MaterialEntity" xsd:string
property_value: IAO:0000112 "a flame" xsd:string
property_value: IAO:0000112 "a forest fire" xsd:string
property_value: IAO:0000112 "a human being" xsd:string
property_value: IAO:0000112 "a hurricane" xsd:string
property_value: IAO:0000112 "a photon" xsd:string
property_value: IAO:0000112 "a puff of smoke" xsd:string
property_value: IAO:0000112 "a sea wave" xsd:string
property_value: IAO:0000112 "a tornado" xsd:string
property_value: IAO:0000112 "an aggregate of human beings." xsd:string
property_value: IAO:0000112 "an energy wave" xsd:string
property_value: IAO:0000112 "an epidemic" xsd:string
property_value: IAO:0000112 "the undetached arm of a human being" xsd:string
property_value: IAO:0000116 "BFO 2 Reference: Material entities (continuants) can preserve their identity even while gaining and losing material parts. Continuants are contrasted with occurrents, which unfold themselves in successive temporal parts or phases [60" xsd:string
property_value: IAO:0000116 "BFO 2 Reference: Object, Fiat Object Part and Object Aggregate are not intended to be exhaustive of Material Entity. Users are invited to propose new subcategories of Material Entity." xsd:string
property_value: IAO:0000116 "BFO 2 Reference: ‘Matter’ is intended to encompass both mass and energy (we will address the ontological treatment of portions of energy in a later version of BFO). A portion of matter is anything that includes elementary particles among its proper or improper parts: quarks and leptons, including electrons, as the smallest particles thus far discovered; baryons (including protons and neutrons) at a higher level of granularity; atoms and molecules at still higher levels, forming the cells, organs, organisms and other material entities studied by biologists, the portions of rock studied by geologists, the fossils studied by paleontologists, and so on.Material entities are three-dimensional entities (entities extended in three spatial dimensions), as contrasted with the processes in which they participate, which are four-dimensional entities (entities extended also along the dimension of time).According to the FMA, material entities may have immaterial entities as parts – including the entities identified below as sites; for example the interior (or ‘lumen’) of your small intestine is a part of your body. BFO 2.0 embodies a decision to follow the FMA here." xsd:string
property_value: IAO:0000600 "A material entity is an independent continuant that has some portion of matter as proper or improper continuant part. (axiom label in BFO2 Reference: [019-002])" xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/019-002"}
property_value: IAO:0000601 "every entity of which a material entity is continuant part is also a material entity. (axiom label in BFO2 Reference: [021-002])" xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/021-002"}
property_value: IAO:0000601 "Every entity which has a material entity as continuant part is a material entity. (axiom label in BFO2 Reference: [020-002])" xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/020-002"}
property_value: IAO:0000602 "(forall (x) (if (and (Entity x) (exists (y t) (and (MaterialEntity y) (continuantPartOfAt x y t)))) (MaterialEntity x))) // axiom label in BFO2 CLIF: [021-002] " xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/021-002"}
property_value: IAO:0000602 "(forall (x) (if (and (Entity x) (exists (y t) (and (MaterialEntity y) (continuantPartOfAt y x t)))) (MaterialEntity x))) // axiom label in BFO2 CLIF: [020-002] " xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/020-002"}
property_value: IAO:0000602 "(forall (x) (if (MaterialEntity x) (IndependentContinuant x))) // axiom label in BFO2 CLIF: [019-002] " xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/019-002"}
property_value: isDefinedBy http://purl.obolibrary.org/obo/bfo.owl
[Term]
id: CARO:0000000
name: anatomical entity
is_a: CARO:0030000 ! biological entity
property_value: IAO:0000412 http://purl.obolibrary.org/obo/caro.owl
[Term]
id: CARO:0030000
name: biological entity
is_a: BFO:0000004 ! independent continuant
[Term]
id: DDANAT:0000002
name: vegetative amoebae
namespace: Dictyostelium_discoideum_anatomy
def: "Unicellular haploid myxamoebae that feeds on bacteria by phagocytosis and divides by binary fission. The size of vegetative cells range from 12-20 microns by 8-12 microns. The cells exhibit a roughly rounded but rather irregular shape." [DDB:pg, PMID:4338436]
synonym: "amoebae" BROAD []
synonym: "vegetative cell" EXACT []
synonym: "vegetative cell (sensu Mycetozoa)" EXACT [CL:0000263]
xref: CL:0000263 "Cell Line Ontology"
is_a: DDANAT:0000083 ! Dictyostelium discoideum single cell organism
relationship: develops_from DDANAT:0000414 ! spore
relationship: part_of DDANAT:0000013 ! stream
[Term]
id: DDANAT:0000003
name: aggregation territory
namespace: Dictyostelium_discoideum_anatomy
def: "Area covered by a group of chemotactic cells converging toward the same aggregation center. Can reach a diameter of up to 1 cm." [DDB:pg, PMID:14458213, PMID:20268085]
is_a: DDANAT:0010082 ! whole organism
[Term]
id: DDANAT:0000004
name: loose aggregate
namespace: Dictyostelium_discoideum_anatomy
def: "First adherent mass of cells observed during development, relatively flat with indistinct borders." [DDB:pg]
synonym: "loose mound" EXACT []
is_a: DDANAT:0010082 ! whole organism
relationship: develops_from DDANAT:0000003 ! aggregation territory
[Term]
id: DDANAT:0000005
name: mound
namespace: Dictyostelium_discoideum_anatomy
def: "Hemispherical structure composed of post-aggregative cells that are undergoing differentiation." [DDB:pg, PMID:20268085]
synonym: "pseudoplasmodium" BROAD [PMID:18366659]
synonym: "tight aggregate" EXACT []
synonym: "tight mound" EXACT []
is_a: DDANAT:0010082 ! whole organism
relationship: develops_from DDANAT:0000004 ! loose aggregate
[Term]
id: DDANAT:0000006
name: tipped mound
namespace: Dictyostelium_discoideum_anatomy
def: "Hemispherical structure composed of post-aggregative cells that are undergoing differentiation and that have formed a tip." [DDB:pg, PMID:20268085]
synonym: "pseudoplasmodium" BROAD []
synonym: "tipped aggregate" EXACT [PMID:7553878]
is_a: DDANAT:0010082 ! whole organism
relationship: develops_from DDANAT:0000005 ! mound
[Term]
id: DDANAT:0000007
name: standing slug
namespace: Dictyostelium_discoideum_anatomy
def: "Cylindrical structure that is formed by elongation of the mound under the control of the tip. The elongating tip is called the first finger." [DDB:pg, PMID:18366659]
comment: Synonym from Kessin book p. 166.
synonym: "finger" EXACT []
synonym: "first finger" NARROW []
synonym: "pseudoplasmodium" BROAD []
xref: ISBN:0521583640
is_a: DDANAT:0010082 ! whole organism
relationship: develops_from DDANAT:0000006 ! tipped mound
[Term]
id: DDANAT:0000008
name: migratory slug
namespace: Dictyostelium_discoideum_anatomy
def: "When the conditions are not optimal for the completion of development, the standing slug bends from a vertical position to a horizontal position, producing a migratory that slug has the ability to migrate towards more favorable environmental conditions. The slug is cylindrical in shape with a rounded, tapering region at its anterior end that is raised with respect to the substratum. It usually measures between 0.8 to 1.2 mm in length with a diameter of 0.15 to 0.25 mm. Slugs sense and respond to light, temperature and acidity, and do not enter culmination until the conditions are optimal. The slug can move at a speed of 0.5 to 2 mm per hour. A trail of slime is deposited on the surface during migration." [DDB:pg, PMID:2513127, PMID:8223266]
synonym: "pseudoplasmodium" BROAD [PMID:18366659]
is_a: DDANAT:0010082 ! whole organism
relationship: develops_from DDANAT:0000007 ! standing slug
[Term]
id: DDANAT:0000009
name: early culminant
namespace: Dictyostelium_discoideum_anatomy
def: "Structure formed after the arrest of slug migration formed when cells of the posterior region of the slug move under the tip. Stalk tube formation is initiated at this stage." [DDB:pg, PMID:18366659, PMID:1879341]
synonym: "culminant" BROAD []
synonym: "mexican hat" NARROW []
synonym: "pseudoplasmodium" BROAD [PMID:18366659]
is_a: DDANAT:0010082 ! whole organism
relationship: develops_from DDANAT:0000007 ! standing slug
[Term]
id: DDANAT:0000010
name: mid culminant
namespace: Dictyostelium_discoideum_anatomy
def: "Structure in which stalk tube formation has progressed down the prespore zone. Basal disc formation begins at this stage, with the migration of pstA and pstB cells to the lower part of the culminant to form the basal disc." [DDB:pg, PMID:9799430]
synonym: "culminant" BROAD []
synonym: "pseudoplasmodium" BROAD [PMID:18366659]
is_a: DDANAT:0010082 ! whole organism
relationship: develops_from DDANAT:0000009 ! early culminant
[Term]
id: DDANAT:0000011
name: late culminant
namespace: Dictyostelium_discoideum_anatomy
def: "Structure in which stalk tube formation has progressed down to the basal disc. The sorogen ascents up the stalk to it apical position during this stage. Terminal differentiation occurs at this stage: death of the stalk cells and encapsulation of the spores." [DDB:pg, PMID:1879341]
comment: Kessin book p. 201.
synonym: "culminant" BROAD []
synonym: "pseudoplasmodium" RELATED [PMID:18366659]
xref: ISBN:0521583640
is_a: DDANAT:0010082 ! whole organism
relationship: develops_from DDANAT:0000010 ! mid culminant
[Term]
id: DDANAT:0000012
name: fruiting body
namespace: Dictyostelium_discoideum_anatomy
def: "Dicty asexual organism which is terminally differentiated and consists of a long stalk on top of which sits the sorus that contains spores. The mature fruiting body measures between 1.5 to 3 mm in height." [DDB:18366659, DDB:pg]
comment: Synonym from Kessin book p. 12-13.
synonym: "sorocarp" EXACT []
xref: ISBN:0521583640
is_a: DDANAT:0010082 ! whole organism
relationship: develops_from DDANAT:0000011 ! late culminant
[Term]
id: DDANAT:0000013
name: stream
namespace: Dictyostelium_discoideum_anatomy
def: "Macroscopic appearance of groups of chemotactic cells orienting themselves in a head to tail fashion as they are migrating in the direction of the chemotactic stimulus to form aggregates." [DDB:18366659, DDB:pg]
synonym: "pseudoplasmodial stream" EXACT []
is_a: DDANAT:0010085 ! subdivision
relationship: part_of DDANAT:0000003 ! aggregation territory
[Term]
id: DDANAT:0000017
name: prespore region of the tipped mound
namespace: Dictyostelium_discoideum_anatomy
def: "Region of the tipped mound mostly composed of prespore cells. In addition to prespore cells, the prespore region contains anterior-like cells (ALC) that express ecmA and/or ecmB." [DDB:pg]
synonym: "psp region of the tipped mound" EXACT []
is_a: DDANAT:0000086 ! prespore region
relationship: develops_from DDANAT:0000005 ! mound
relationship: part_of DDANAT:0000006 ! tipped mound
[Term]
id: DDANAT:0000024
name: prespore region of the standing slug
namespace: Dictyostelium_discoideum_anatomy
def: "Region of the standing slug mostly composed of prespore cells. In addition to prespore cells, the prespore region contains anterior-like cells (ALC) that express ecmA and/or ecmB. The prespore region occupies about three quarters of the organism." [DDB:pg]
synonym: "psp region of the standing slug" EXACT []
is_a: DDANAT:0000086 ! prespore region
relationship: develops_from DDANAT:0000017 ! prespore region of the tipped mound
relationship: part_of DDANAT:0000007 ! standing slug
[Term]
id: DDANAT:0000033
name: prespore region of the migratory slug
namespace: Dictyostelium_discoideum_anatomy
def: "Region of the migratory slug composed mostly of prespore cells. In addition to prespore cells, the prespore region contains anterior-like cells (ALC) that express ecmA and/or ecmB. The prespore region occupies about three quarters of the organism." [DDB:pg]
synonym: "psp region of the migratory slug" BROAD []
is_a: DDANAT:0000086 ! prespore region
relationship: develops_from DDANAT:0000024 ! prespore region of the standing slug
relationship: part_of DDANAT:0000008 ! migratory slug
[Term]
id: DDANAT:0000041
name: prespore region of the early culminant
namespace: Dictyostelium_discoideum_anatomy
def: "Region of the early culminant mostly composed of prespore cells. In addition to prespore cells, the prespore region contains anterior-like cells (ALC) that express ecmA and/or ecmB. The prespore region occupies about three quarters of the organism." [DDB:pg]
synonym: "psp region of the early culminant" EXACT []
is_a: DDANAT:0000086 ! prespore region
relationship: develops_from DDANAT:0000024 ! prespore region of the standing slug
relationship: part_of DDANAT:0000009 ! early culminant
[Term]
id: DDANAT:0000054
name: prespore region of the mid culminant
namespace: Dictyostelium_discoideum_anatomy
def: "Region of the mid culminant mostly composed of prespore cells. In addition to prespore cells, the prespore region contains anterior-like cells (ALC) that express ecmA and/or ecmB. The prespore region occupies about three quarters of the organism." [DDB:pg]
synonym: "psp region of the mid culminant" BROAD []
is_a: DDANAT:0000086 ! prespore region
relationship: develops_from DDANAT:0000041 ! prespore region of the early culminant
relationship: part_of DDANAT:0000010 ! mid culminant
[Term]
id: DDANAT:0000061
name: sorus of the late culminant
namespace: Dictyostelium_discoideum_anatomy
def: "Ovoid structure of the late culminant supported by the stalk and that contains the spores." [DDB:pg, ISBN:0198529171]
synonym: "spore head of the late culminant" EXACT []
is_a: DDANAT:0000094 ! sorus
relationship: develops_from DDANAT:0000054 ! prespore region of the mid culminant
relationship: part_of DDANAT:0000011 ! late culminant
[Term]
id: DDANAT:0000070
name: sorus of the fruiting body
namespace: Dictyostelium_discoideum_anatomy
def: "Structure of the fruiting body supported by the stalk and that contains the spores. The sorus is 125-300 microns in diameter, lemon-shaped, and grayish white to pale yellow in color." [DDB:pg]
synonym: "spore head of the fruiting body" EXACT []
is_a: DDANAT:0000094 ! sorus
relationship: develops_from DDANAT:0000061 ! sorus of the late culminant
relationship: part_of DDANAT:0000012 ! fruiting body
[Term]
id: DDANAT:0000083
name: Dictyostelium discoideum single cell organism
namespace: Dictyostelium_discoideum_anatomy
def: "Cell that is an individual member of the species Dictyostelium discoideum." [CARO:MAH, DDB:PG]
synonym: "Dictyostelium discoideum single cell organism" EXACT []
xref: CARO:0000064
is_a: DDANAT:0000401 ! cell
[Term]
id: DDANAT:0000086
name: prespore region
namespace: Dictyostelium_discoideum_anatomy
def: "Region mostly composed of prespore cells. In addition to prespore cells, the prespore region contains anterior-like cells (ALC) that express ecmA and/or ecmB. The prespore region occupies about three quarters of the organism." [DDB:pg]
synonym: "psp region" EXACT []
is_a: DDANAT:0010085 ! subdivision
[Term]
id: DDANAT:0000094
name: sorus
namespace: Dictyostelium_discoideum_anatomy
def: "Ovoid structure supported by the stalk and that contains the spores." [DDB:pg]
synonym: "spore head" EXACT []
is_a: DDANAT:0010085 ! subdivision
[Term]
id: DDANAT:0000401
name: cell
namespace: Dictyostelium_discoideum_anatomy
def: "Anatomical structure that has as its parts a maximally connected cell compartment surrounded by a plasma membrane." [CARO:MAH]
is_a: DDANAT:0010001 ! Dictyostelium discoideum anatomical structure
[Term]
id: DDANAT:0000402
name: chemotactic amoeboid cell
namespace: Dictyostelium_discoideum_anatomy
def: "Starved cell that secretes and responds to chemoattractants (cAMP)." [DDB:pg, PMID:4338436]
synonym: "amoebae" BROAD []
synonym: "chemotactic amoeboid cell (sensu Mycetozoa)" EXACT [CL:0000289]
xref: CL:0000289 "Cell Line Ontology"
is_a: DDANAT:0000083 ! Dictyostelium discoideum single cell organism
relationship: develops_from DDANAT:0000414 ! spore
relationship: part_of DDANAT:0000013 ! stream
[Term]
id: DDANAT:0000403
name: aggregate cell
namespace: Dictyostelium_discoideum_anatomy
def: "Differentiating cell composing the aggregate that has acquired adhesive properties." [DDB:pg]
xref: CL:0000259 "Cell Line Ontology"
is_a: DDANAT:0000401 ! cell
relationship: develops_from DDANAT:0000402 ! chemotactic amoeboid cell
relationship: part_of DDANAT:0000003 ! aggregation territory
relationship: part_of DDANAT:0000004 ! loose aggregate
relationship: part_of DDANAT:0000005 ! mound
[Term]
id: DDANAT:0000405
name: prespore cell
namespace: Dictyostelium_discoideum_anatomy
def: "Cell that is undergoing differentiation to become a spore. Characterized by the presence of prespore vesicles (PV)." [DDB:pg, PMID:4330277]
synonym: "psp cell" EXACT []
xref: CL:0000267 "Cell Line Ontology"
is_a: DDANAT:0000401 ! cell
relationship: develops_from DDANAT:0000403 ! aggregate cell
relationship: part_of DDANAT:0000004 ! loose aggregate
relationship: part_of DDANAT:0000017 ! prespore region of the tipped mound
relationship: part_of DDANAT:0000024 ! prespore region of the standing slug
relationship: part_of DDANAT:0000033 ! prespore region of the migratory slug
relationship: part_of DDANAT:0000041 ! prespore region of the early culminant
relationship: part_of DDANAT:0000054 ! prespore region of the mid culminant
relationship: part_of DDANAT:0000061 ! sorus of the late culminant
[Term]
id: DDANAT:0000414
name: spore
namespace: Dictyostelium_discoideum_anatomy
def: "Dormant cell protected by a tri-layer spore coat. The spore has an elliptical shape and is approximately 6-9 microns by 3 microns." [DDB:pg, PMID:4338436]
synonym: "spore (sensu Mycetozoa)" EXACT [CL:0000291]
xref: CL:0000291 "Cell Line Ontology"
is_a: DDANAT:0000083 ! Dictyostelium discoideum single cell organism
relationship: develops_from DDANAT:0000405 ! prespore cell
relationship: part_of DDANAT:0000070 ! sorus of the fruiting body
[Term]
id: DDANAT:0010001
name: Dictyostelium discoideum anatomical structure
namespace: Dictyostelium_discoideum_anatomy
alt_id: DDANAT:0000001
def: "Material anatomical entity that has inherent 3D shape and is generated by coordinated expression of the Dictyostelium discoideum genome." [CARO:MAH]
[Term]
id: DDANAT:0010082
name: whole organism
namespace: Dictyostelium_discoideum_anatomy
alt_id: DDANAT:0000082
def: "Anatomical structure that is an individual member of the Dictyostelium discoideum species and consists of more than one cell." [CARO:MAH]
xref: CARO:0000012
is_a: DDANAT:0010001 ! Dictyostelium discoideum anatomical structure
[Term]
id: DDANAT:0010085
name: subdivision
namespace: Dictyostelium_discoideum_anatomy
alt_id: DDANAT:0000085
def: "Anatomical structure which is a primary subdivision of whole Dictyostelium organism. The mereological sum of these is the whole organism." [DDB:pg]
xref: CARO:0000032
is_a: DDANAT:0010001 ! Dictyostelium discoideum anatomical structure
[Term]
id: DDPHENO:00000000
name: root node
[Term]
id: GO:0003674
name: molecular_function
namespace: molecular_function
alt_id: GO:0005554
def: "A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs. These actions are described from two distinct but related perspectives: (1) biochemical activity, and (2) role as a component in a larger system/process." [GOC:pdt]
comment: Note that, in addition to forming the root of the molecular function ontology, this term is recommended for use for the annotation of gene products whose molecular function is unknown. When this term is used for annotation, it indicates that no information was available about the molecular function of the gene product annotated as of the date the annotation was made; the evidence code "no data" (ND), is used to indicate this. Despite its name, this is not a type of 'function' in the sense typically defined by upper ontologies such as Basic Formal Ontology (BFO). It is instead a BFO:process carried out by a single gene product or complex.
subset: goslim_aspergillus
subset: goslim_candida
subset: goslim_chembl
subset: goslim_generic
subset: goslim_metagenomics
subset: goslim_pir
subset: goslim_plant
subset: goslim_yeast
synonym: "molecular function" EXACT []
is_a: BFO:0000015 ! process
property_value: IAO:0000589 "molecular process" xsd:string
[Term]
id: GO:0003824
name: catalytic activity
namespace: molecular_function
def: "Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic." [GOC:vw, ISBN:0198506732]
subset: goslim_chembl
subset: goslim_flybase_ribbon
subset: goslim_metagenomics
subset: goslim_pir
subset: goslim_plant
synonym: "enzyme activity" EXACT [GOC:dph, GOC:tb]
xref: Wikipedia:Enzyme
is_a: GO:0003674 ! molecular_function
[Term]
id: GO:0005102
name: signaling receptor binding
namespace: molecular_function
def: "Interacting selectively and non-covalently with one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function." [GOC:bf, GOC:ceb, ISBN:0198506732]
comment: Where appropriate, also consider annotating to 'receptor agonist activity ; GO:0048018'.
subset: goslim_agr
subset: goslim_chembl
subset: goslim_flybase_ribbon
subset: goslim_mouse
subset: goslim_plant
synonym: "receptor binding" BROAD []
synonym: "receptor ligand" NARROW []
synonym: "receptor-associated protein activity" RELATED []
xref: Wikipedia:Ligand_(biochemistry)
is_a: GO:0005515 ! protein binding
[Term]
id: GO:0005488
name: binding
namespace: molecular_function
def: "The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule." [GOC:ceb, GOC:mah, ISBN:0198506732]
comment: Note that this term is in the subset of terms that should not be used for direct, manual gene product annotation. Please choose a more specific child term, or request a new one if no suitable term is available. For ligands that bind to signal transducing receptors, consider the molecular function term 'receptor binding ; GO:0005102' and its children.
subset: gocheck_do_not_manually_annotate
subset: goslim_pir
subset: goslim_plant
synonym: "ligand" NARROW []
xref: Wikipedia:Binding_(molecular)
is_a: GO:0003674 ! molecular_function
[Term]
id: GO:0005515
name: protein binding
namespace: molecular_function
alt_id: GO:0001948
alt_id: GO:0045308
def: "Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules)." [GOC:go_curators]
subset: goslim_aspergillus
subset: goslim_candida
subset: goslim_chembl
subset: goslim_metagenomics
subset: goslim_pir
subset: goslim_plant
synonym: "glycoprotein binding" NARROW []
synonym: "protein amino acid binding" EXACT []
xref: reactome:R-HSA-170835 "An anchoring protein, ZFYVE9 (SARA), recruits SMAD2/3"
xref: reactome:R-HSA-170846 "TGFBR2 recruits TGFBR1"
xref: reactome:R-HSA-3645786 "TGFBR2 mutant dimers recruit TGFBR1"
xref: reactome:R-HSA-3656484 "TGFBR2 recruits TGFBR1 KD Mutants"
xref: reactome:R-HSA-3702153 "An anchoring protein, ZFYVE9 (SARA), recruits SMAD2/3 MH2 domain mutants"
xref: reactome:R-HSA-3713560 "An anchoring protein, ZFYVE9 (SARA), recruits SMAD2/3 phosphorylation motif mutants"
is_a: GO:0005488 ! binding
[Term]
id: GO:0006793
name: phosphorus metabolic process
namespace: biological_process
def: "The chemical reactions and pathways involving the nonmetallic element phosphorus or compounds that contain phosphorus, usually in the form of a phosphate group (PO4)." [GOC:ai]
subset: goslim_pir
synonym: "phosphorus metabolism" EXACT []
is_a: GO:0044237 ! cellular metabolic process
[Term]
id: GO:0006796
name: phosphate-containing compound metabolic process
namespace: biological_process
def: "The chemical reactions and pathways involving the phosphate group, the anion or salt of any phosphoric acid." [GOC:ai]
synonym: "phosphate metabolic process" RELATED []
synonym: "phosphate metabolism" EXACT []
is_a: GO:0006793 ! phosphorus metabolic process
[Term]
id: GO:0007154
name: cell communication
namespace: biological_process
def: "Any process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment." [GOC:mah]
subset: goslim_pir
subset: goslim_plant
xref: Wikipedia:Cell_signaling
is_a: GO:0009987 ! cellular process
[Term]
id: GO:0007165
name: signal transduction
namespace: biological_process
alt_id: GO:0023033
def: "The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell." [GOC:go_curators, GOC:mtg_signaling_feb11]
comment: Note that signal transduction is defined broadly to include a ligand interacting with a receptor, downstream signaling steps and a response being triggered. A change in form of the signal in every step is not necessary. Note that in many cases the end of this process is regulation of the initiation of transcription. Note that specific transcription factors may be annotated to this term, but core/general transcription machinery such as RNA polymerase should not.
subset: goslim_aspergillus
subset: goslim_candida
subset: goslim_chembl
subset: goslim_generic
subset: goslim_metagenomics
subset: goslim_plant
synonym: "signaling cascade" NARROW []
synonym: "signaling pathway" RELATED []
synonym: "signalling cascade" NARROW []
synonym: "signalling pathway" RELATED [GOC:mah]
xref: Wikipedia:Signal_transduction
is_a: GO:0009987 ! cellular process
is_a: GO:0050794 ! regulation of cellular process
relationship: part_of GO:0007154 ! cell communication
relationship: part_of GO:0023052 ! signaling
relationship: part_of GO:0051716 ! cellular response to stimulus
[Term]
id: GO:0008150
name: biological_process
namespace: biological_process
alt_id: GO:0000004
alt_id: GO:0007582
alt_id: GO:0044699
def: "A biological process represents a specific objective that the organism is genetically programmed to achieve. Biological processes are often described by their outcome or ending state, e.g., the biological process of cell division results in the creation of two daughter cells (a divided cell) from a single parent cell. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence." [GOC:pdt]
comment: Note that, in addition to forming the root of the biological process ontology, this term is recommended for use for the annotation of gene products whose biological process is unknown. When this term is used for annotation, it indicates that no information was available about the biological process of the gene product annotated as of the date the annotation was made; the evidence code "no data" (ND), is used to indicate this.
subset: goslim_aspergillus
subset: goslim_candida
subset: goslim_chembl
subset: goslim_generic
subset: goslim_metagenomics
subset: goslim_pir
subset: goslim_plant
subset: goslim_pombe
subset: goslim_yeast
synonym: "biological process" EXACT []
synonym: "physiological process" EXACT []
synonym: "single organism process" RELATED []
synonym: "single-organism process" RELATED []
xref: Wikipedia:Biological_process
is_a: BFO:0000015 ! process
created_by: janelomax
creation_date: 2012-09-19T15:05:24Z
[Term]
id: GO:0008152
name: metabolic process
namespace: biological_process
alt_id: GO:0044236
alt_id: GO:0044710
def: "The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation." [GOC:go_curators, ISBN:0198547684]
comment: Note that metabolic processes do not include single functions or processes such as protein-protein interactions, protein-nucleic acids, nor receptor-ligand interactions.
subset: gocheck_do_not_manually_annotate
subset: goslim_chembl
subset: goslim_metagenomics
subset: goslim_pir
subset: goslim_plant
synonym: "metabolic process resulting in cell growth" NARROW []
synonym: "metabolism" EXACT []
synonym: "metabolism resulting in cell growth" NARROW []
synonym: "multicellular organism metabolic process" NARROW []
synonym: "single-organism metabolic process" RELATED []
xref: Wikipedia:Metabolism
is_a: GO:0008150 ! biological_process
created_by: janelomax
creation_date: 2012-10-17T15:46:40Z
[Term]
id: GO:0009892
name: negative regulation of metabolic process
namespace: biological_process
alt_id: GO:0044252
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism." [GOC:go_curators]
synonym: "down regulation of metabolic process" EXACT []
synonym: "down-regulation of metabolic process" EXACT []
synonym: "downregulation of metabolic process" EXACT []
synonym: "inhibition of metabolic process" NARROW []
synonym: "inhibition of organismal metabolic process" NARROW []
synonym: "negative regulation of metabolism" EXACT []
synonym: "negative regulation of multicellular organismal metabolic process" NARROW []
synonym: "negative regulation of organismal metabolism" EXACT []
is_a: GO:0019222 ! regulation of metabolic process
is_a: GO:0048519 ! negative regulation of biological process
intersection_of: GO:0008150 ! biological_process
intersection_of: negatively_regulates GO:0008152 ! metabolic process
relationship: negatively_regulates GO:0008152 ! metabolic process
[Term]
id: GO:0009893
name: positive regulation of metabolic process
namespace: biological_process
alt_id: GO:0044253
def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism." [GOC:go_curators]
synonym: "activation of metabolic process" NARROW []
synonym: "positive regulation of metabolism" EXACT []
synonym: "positive regulation of multicellular organismal metabolic process" NARROW []
synonym: "positive regulation of organismal metabolism" NARROW []
synonym: "stimulation of metabolic process" NARROW []
synonym: "stimulation of organismal metabolic process" NARROW []
synonym: "up regulation of metabolic process" EXACT []
synonym: "up-regulation of metabolic process" EXACT []
synonym: "up-regulation of organismal metabolic process" NARROW []
synonym: "upregulation of metabolic process" EXACT []
is_a: GO:0019222 ! regulation of metabolic process
is_a: GO:0048518 ! positive regulation of biological process
intersection_of: GO:0008150 ! biological_process
intersection_of: positively_regulates GO:0008152 ! metabolic process
relationship: positively_regulates GO:0008152 ! metabolic process
[Term]
id: GO:0009966
name: regulation of signal transduction
namespace: biological_process
alt_id: GO:0035466
def: "Any process that modulates the frequency, rate or extent of signal transduction." [GOC:sm]
synonym: "regulation of signaling pathway" RELATED []
synonym: "regulation of signalling pathway" RELATED [GOC:mah]
is_a: GO:0010646 ! regulation of cell communication
is_a: GO:0023051 ! regulation of signaling
is_a: GO:0048583 ! regulation of response to stimulus
intersection_of: GO:0008150 ! biological_process
intersection_of: regulates GO:0007165 ! signal transduction
relationship: regulates GO:0007165 ! signal transduction
[Term]
id: GO:0009967
name: positive regulation of signal transduction
namespace: biological_process
alt_id: GO:0035468
def: "Any process that activates or increases the frequency, rate or extent of signal transduction." [GOC:sm]
synonym: "activation of signal transduction" NARROW []
synonym: "positive regulation of signaling pathway" RELATED []
synonym: "positive regulation of signalling pathway" RELATED [GOC:mah]
synonym: "stimulation of signal transduction" NARROW []
synonym: "up regulation of signal transduction" EXACT []
synonym: "up-regulation of signal transduction" EXACT []
synonym: "upregulation of signal transduction" EXACT []
is_a: GO:0009966 ! regulation of signal transduction
is_a: GO:0010647 ! positive regulation of cell communication
is_a: GO:0023056 ! positive regulation of signaling
is_a: GO:0048584 ! positive regulation of response to stimulus
intersection_of: GO:0008150 ! biological_process
intersection_of: positively_regulates GO:0007165 ! signal transduction
relationship: positively_regulates GO:0007165 ! signal transduction
[Term]
id: GO:0009968
name: negative regulation of signal transduction
namespace: biological_process
alt_id: GO:0035467
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction." [GOC:sm]
synonym: "down regulation of signal transduction" EXACT []
synonym: "down-regulation of signal transduction" EXACT []
synonym: "downregulation of signal transduction" EXACT []
synonym: "inhibition of signal transduction" NARROW []
synonym: "negative regulation of signaling pathway" RELATED []
synonym: "negative regulation of signalling pathway" RELATED [GOC:mah]
is_a: GO:0009966 ! regulation of signal transduction
is_a: GO:0010648 ! negative regulation of cell communication
is_a: GO:0023057 ! negative regulation of signaling
is_a: GO:0048585 ! negative regulation of response to stimulus
intersection_of: GO:0008150 ! biological_process
intersection_of: negatively_regulates GO:0007165 ! signal transduction
relationship: negatively_regulates GO:0007165 ! signal transduction
[Term]
id: GO:0009987
name: cellular process
namespace: biological_process
alt_id: GO:0008151
alt_id: GO:0044763
alt_id: GO:0050875
def: "Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level." [GOC:go_curators, GOC:isa_complete]
subset: goslim_plant
synonym: "cell growth and/or maintenance" NARROW []
synonym: "cell physiology" EXACT []
synonym: "cellular physiological process" EXACT []
synonym: "single-organism cellular process" RELATED []
is_a: GO:0008150 ! biological_process
created_by: janelomax
creation_date: 2012-12-11T16:56:55Z
[Term]
id: GO:0010469
name: regulation of signaling receptor activity
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of a signaling receptor activity. Receptor activity is when a molecule combines with an extracellular or intracellular messenger to initiate a change in cell activity." [GOC:dph, GOC:tb]
synonym: "regulation of receptor activity" BROAD []
is_a: GO:0009966 ! regulation of signal transduction
is_a: GO:0065009 ! regulation of molecular function
intersection_of: GO:0008150 ! biological_process
intersection_of: regulates GO:0038023 ! signaling receptor activity
relationship: regulates GO:0038023 ! signaling receptor activity
[Term]
id: GO:0010562
name: positive regulation of phosphorus metabolic process
namespace: biological_process
def: "Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus." [GOC:dph, GOC:tb]
is_a: GO:0031325 ! positive regulation of cellular metabolic process
is_a: GO:0051174 ! regulation of phosphorus metabolic process
intersection_of: GO:0008150 ! biological_process
intersection_of: positively_regulates GO:0006793 ! phosphorus metabolic process
relationship: positively_regulates GO:0006793 ! phosphorus metabolic process
[Term]
id: GO:0010563
name: negative regulation of phosphorus metabolic process
namespace: biological_process
def: "Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus." [GOC:dph, GOC:tb]
is_a: GO:0031324 ! negative regulation of cellular metabolic process
is_a: GO:0051174 ! regulation of phosphorus metabolic process
intersection_of: GO:0008150 ! biological_process
intersection_of: negatively_regulates GO:0006793 ! phosphorus metabolic process
relationship: negatively_regulates GO:0006793 ! phosphorus metabolic process
[Term]
id: GO:0010646
name: regulation of cell communication
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment." [GOC:dph, GOC:tb]
is_a: GO:0050794 ! regulation of cellular process
intersection_of: GO:0008150 ! biological_process
intersection_of: regulates GO:0007154 ! cell communication
relationship: regulates GO:0007154 ! cell communication
[Term]
id: GO:0010647
name: positive regulation of cell communication
namespace: biological_process
def: "Any process that increases the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment." [GOC:dph, GOC:tb]
is_a: GO:0010646 ! regulation of cell communication
is_a: GO:0048522 ! positive regulation of cellular process
intersection_of: GO:0008150 ! biological_process
intersection_of: positively_regulates GO:0007154 ! cell communication
relationship: positively_regulates GO:0007154 ! cell communication
[Term]
id: GO:0010648
name: negative regulation of cell communication
namespace: biological_process
def: "Any process that decreases the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment." [GOC:dph, GOC:tb]
is_a: GO:0010646 ! regulation of cell communication
is_a: GO:0048523 ! negative regulation of cellular process
intersection_of: GO:0008150 ! biological_process
intersection_of: negatively_regulates GO:0007154 ! cell communication
relationship: negatively_regulates GO:0007154 ! cell communication
[Term]
id: GO:0016301
name: kinase activity
namespace: molecular_function
def: "Catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule." [ISBN:0198506732]
comment: Note that this term encompasses all activities that transfer a single phosphate group; although ATP is by far the most common phosphate donor, reactions using other phosphate donors are included in this term.
subset: goslim_chembl
subset: goslim_generic
subset: goslim_metagenomics
subset: goslim_plant
subset: goslim_yeast
synonym: "phosphokinase activity" EXACT []
xref: reactome:R-HSA-109822 "MAPK3,(MAPK1) phosphorylates GRB2-1:SOS1:p-Y427-SHC1"
xref: reactome:R-HSA-109823 "MAPK3,(MAPK1) phosphorylates GRB2-1:SOS1:p-Y-IRS1,p-Y-IRS2"
xref: reactome:R-HSA-111898 "Phosphorylation of cPLA2 by ERK-2"
xref: reactome:R-HSA-112381 "Hyperphosphorylation (Ser2) of RNA Pol II CTD by P-TEFb complex"
xref: reactome:R-HSA-139908 "Phosphorylation of DLC2 by MAPK8"
xref: reactome:R-HSA-139918 "Phosphorylation of BIM by JNK"
xref: reactome:R-HSA-165692 "Phosphorylation of 4E-BP1 by activated mTORC1"
xref: reactome:R-HSA-165718 "mTORC1 phosphorylation of RPS6KB1 (S6K)"
xref: reactome:R-HSA-165726 "Phosphorylation of Ribosomal protein S6 by activated S6K1"
xref: reactome:R-HSA-165758 "Phosphorylation and inactivation of eEF2K by activated S6K1"
xref: reactome:R-HSA-165766 "Phosphorylation and activation of eIF4G by activated S6K1"
xref: reactome:R-HSA-165777 "Phosphorylation and activation of eIF4B by activated S6K1"
xref: reactome:R-HSA-167084 "Hyperphosphorylation (Ser2) of RNA Pol II CTD by P-TEFb complex"
xref: reactome:R-HSA-167098 "Phosphorylation (Ser5) of RNA pol II CTD"
xref: reactome:R-HSA-167191 "Hyperphosphorylation (Ser2) of RNA Pol II CTD by the P-TEFb(Cyclin T1:Cdk9) complex"
xref: reactome:R-HSA-170055 "Myt-1 mediated phosphorylation of Cyclin B:Cdc2 complexes"
xref: reactome:R-HSA-170070 "Wee1-mediated phosphorylation of Cyclin B1:phospho-Cdc2 complexes"
xref: reactome:R-HSA-170076 "CAK-mediated phosphorylation of Cyclin B1:Cdc2 complexes"
xref: reactome:R-HSA-170087 "CAK-mediated phosphorylation of Cyclin A:Cdc2 complexes"
xref: reactome:R-HSA-170116 "Myt-1 mediated phosphorylation of Cyclin A:Cdc2"
xref: reactome:R-HSA-170126 "Phosphorylation of Cyclin B1 in the CRS domain"
xref: reactome:R-HSA-170156 "Wee1-mediated phosphorylation of Cyclin A:phospho-Cdc2 complexes"
xref: reactome:R-HSA-170704 "Phosphorylation of DSIF by the P-TEFb(Cyclin T1:Cdk9) complex"
xref: reactome:R-HSA-170706 "Phosphorylation of NEFL by the P-TEFb(Cyclin T1:Cdk9) complex"
xref: reactome:R-HSA-174164 "Phosphorylation of Cyclin A:Cdk2 at Tyr 15"
xref: reactome:R-HSA-1839091 "Cytosolic FGFR1 fusion protein-associated PI3K phosphorylates PIP2 to PIP3"
xref: reactome:R-HSA-1839107 "BCR-FGFR1-associated PI3K phosphorylates PIP2 to PIP3."
xref: reactome:R-HSA-1839110 "p-BCR-p-FGFR1 phosphorylates GAB2"
xref: reactome:R-HSA-187949 "CAK-mediated phosphorylation of Cyclin A:Cdk2"
xref: reactome:R-HSA-188350 "CAK-mediated phosphorylation of Cyclin E:Cdk2"
xref: reactome:R-HSA-191636 "Phosphorylation of Cx43 by c-src"
xref: reactome:R-HSA-195275 "Phosphorylation of APC component of the destruction complex"
xref: reactome:R-HSA-195283 "Phosphorylation of phospho- (Ser45, Thr41) beta-catenin at Ser37 by GSK-3"
xref: reactome:R-HSA-195287 "Phosphorylation of phospho-(Ser45 ) at Thr 41 by GSK-3"
xref: reactome:R-HSA-195300 "Phosphorylation of phospho-(Ser45,Thr41,Ser37) at Ser33 by GSK-3"
xref: reactome:R-HSA-195318 "Phosphorylation of beta-catenin at Ser45 by CK1 alpha"
xref: reactome:R-HSA-201717 "CSNK2-mediated phosphorylation of DVL"
xref: reactome:R-HSA-211583 "Partial autophosphorylation of PAK-2 at Ser-19, Ser-20, Ser-55, Ser-192, and Ser-197"
xref: reactome:R-HSA-211650 "Autophosphorylation of PAK-2p34 in the activation loop"
xref: reactome:R-HSA-2214351 "PLK1 phosphorylates GORASP1"
xref: reactome:R-HSA-2294580 "PLK1 hyperphosphorylates Condensin II complex"
xref: reactome:R-HSA-2529020 "CK2 phosphorylates condensin I subunits"
xref: reactome:R-HSA-389762 "Phosphorylation of PD-1"
xref: reactome:R-HSA-392752 "Phosphorylation of L1 by CK-II"
xref: reactome:R-HSA-442724 "Phosphorylation of CREB1 by ribosomal protein S6 kinases (RSKs)"
xref: reactome:R-HSA-445079 "Phosphorylation of L1 by ERK"
xref: reactome:R-HSA-5654690 "FGFR1-associated PI3K phosphorylates PIP2 to PIP3"
xref: reactome:R-HSA-5654692 "FGFR1- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3"
xref: reactome:R-HSA-5654697 "FGFR2- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3"
xref: reactome:R-HSA-5654701 "FGFR2-associated PI3K phosphorylates PIP2 to PIP3"
xref: reactome:R-HSA-5654705 "FGFR3-associated PI3K phosphorylates PIP2 to PIP3"
xref: reactome:R-HSA-5654709 "FGFR3- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3"
xref: reactome:R-HSA-5654714 "FGFR4- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3"
xref: reactome:R-HSA-5654717 "FGFR4-associated PI3K phosphorylates PIP2 to PIP3"
xref: reactome:R-HSA-5655235 "Activated FGFR4 mutant-associated PI3K phosphorylates PIP2 to PIP3"
xref: reactome:R-HSA-5655289 "Activated FGFR3 mutant-associated PI3K phosphorylates PIP2 to PIP3"
xref: reactome:R-HSA-5655290 "Activated FGFR1 mutant-associated PI3K phosphorylates PIP2 to PIP3"
xref: reactome:R-HSA-5655323 "Activated FGFR2 mutant-associated PI3K phosphorylates PIP2 to PIP3"
xref: reactome:R-HSA-5668545 "NIK autophosphorylates on T559"
xref: reactome:R-HSA-6788855 "FN3KRP phosphorylates PsiAm, RibAm"
xref: reactome:R-HSA-6788867 "FN3K phosphorylates ketosamines"
xref: reactome:R-HSA-6814409 "CK2 phosphorylates PDCL"
xref: reactome:R-HSA-68954 "Mcm2-7 is phosphorylated by DDK"
xref: reactome:R-HSA-69195 "Phosphorylation of Cyclin E:CDK2 complexes by WEE1"
xref: reactome:R-HSA-69604 "Phosphorylation of Cdc25A at Ser-123 by Chk1"
xref: reactome:R-HSA-75028 "Phosphorylation of Wee1 kinase by Chk1"
xref: reactome:R-HSA-75809 "Phosphorylation of Cdc25C at Ser216 by CHEK2"
xref: reactome:R-HSA-77071 "Phosphorylation (Ser5) of RNA pol II CTD"
xref: reactome:R-HSA-8853323 "Activated FGFR3 fusion-associated PI3K phosphorylates PIP2 to PIP3"
xref: reactome:R-HSA-8942836 "CDK4/6:CCND complexes are activated by T-loop phosphorylation of CDK4/6"
xref: reactome:R-HSA-8948039 "FUNDC1 is phosphorylated by CK2"
xref: reactome:R-HSA-8948143 "p-S13, FUNDC1 is phosphorylated by CK2 at Tyr18"
xref: reactome:R-HSA-8948146 "FUNDC1 is phosphorylated by ULK1 at Ser17"
is_a: GO:0016772 ! transferase activity, transferring phosphorus-containing groups
relationship: part_of GO:0016310 ! phosphorylation
[Term]
id: GO:0016310
name: phosphorylation
namespace: biological_process
def: "The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide." [ISBN:0198506732]
subset: goslim_chembl
subset: goslim_metagenomics