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ingest: deduplicate sequences using strain names #33

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joverlee521 opened this issue Jun 7, 2022 · 1 comment
Open

ingest: deduplicate sequences using strain names #33

joverlee521 opened this issue Jun 7, 2022 · 1 comment
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enhancement New feature or request

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@joverlee521
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Context

Once we've completed #32, we can use strain names to deduplicate sequences.
This is necessary in case different groups sequence the same virus or if sequences are generated from different protocols.
(NOTE: This is separate from the versioning in GenBank, we already pull in the latest version of GenBank sequences).

Description

The duplicate sequences should probably be filtered out in a new script (e.g. ingest/bin/deduplicate-records) OR potentially use the augur deduplicate command (see nextstrain/augur#919).

We probably want to keep a file with all sequences in case people want the duplicate sequences for any reason.
The deduplicated files will be the main ones used for LAPIS and/or our monkeypox builds.

@jameshadfield
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Update: We currently have a duplicate in the hMPX build (MPXV-M5312_HM12_Rivers from accessions MT903340 and NC_063383). It’s not a huge problem as it's not in the current outbreak.

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