diff --git a/setup.py b/setup.py
index a924fe534..863e67fa0 100644
--- a/setup.py
+++ b/setup.py
@@ -61,7 +61,7 @@
         "networkx >= 2.5, <4",
         "numpy ==1.*",
         "packaging >=19.2",
-        "pandas >=1.0.0, ==1.*",
+        "pandas >=1.0.0, <3",
         "phylo-treetime >=0.11.2, <0.12",
         "pyfastx >=1.0.0, <3.0",
         "python_calamine >=0.2.0",
@@ -76,7 +76,7 @@
             "freezegun >=0.3.15",
             "mypy",
             "nextstrain-sphinx-theme >=2022.5",
-            "pandas-stubs >=1.0.0, ==1.*",
+            "pandas-stubs >=1.0.0, <3",
             "pylint >=1.7.6",
             "pytest >=5.4.1",
             "pytest-cov >=2.8.1",