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How does Modkit handle long-read methylation 3D genomic data #289

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biozzq opened this issue Oct 24, 2024 · 1 comment
Open

How does Modkit handle long-read methylation 3D genomic data #289

biozzq opened this issue Oct 24, 2024 · 1 comment
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question Looking for clarification on inputs and/or outputs

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@biozzq
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biozzq commented Oct 24, 2024

Dear @ALL

I think this question would be more appropriate here, so I referenced it here (nanoporetech/dorado#1089)

Thank you for your time.

Kind regards
Zheng zhuqing

@ArtRand
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ArtRand commented Oct 25, 2024

Hello @biozzq,

There is documentation regarding how to use non-primary alignments in some of the modkit commands. However, as of now pileup does not aggregate non-primary alignments. It's not impossible by any means, but there are some sharp edges so I want to make sure it works correctly first. Are you looking for something like pore-c?

@ArtRand ArtRand added the question Looking for clarification on inputs and/or outputs label Oct 25, 2024
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