diff --git a/sdks/python/setup.py b/sdks/python/setup.py
index a743ff3210de..6a000cf913d9 100644
--- a/sdks/python/setup.py
+++ b/sdks/python/setup.py
@@ -266,7 +266,7 @@ def get_portability_package_data():
             # https://github.com/googleapis/google-cloud-python/issues/10566
             'google-auth>=1.18.0,<3',
             'google-auth-httplib2>=0.1.0,<0.2.0',
-            'google-cloud-datastore>=1.8.0,<2',
+            'google-cloud-datastore>=1.8.0,<3',
             'google-cloud-pubsub>=2.1.0,<3',
             'google-cloud-pubsublite>=1.2.0,<2',
             # GCP packages required by tests