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What we see in Hi-C: Introduction to chromatin biology and sequencing assays, Hi-C data browsing and feature extraction

Welcome to "What we see in Hi-C?" workshop at Genome Architecture and Function 2024 Summer School!

This is a two-part intro to Hi-C data analysis:

  • Part I covers qualitative Hi-C data analysis in interactive browsers (higlass, resgen)
  • Part II shows how to use flexibility of Python programming for whole-genome visualization, compartments, domains and scaling analysis of Hi-C with Open2C tools.

Disclaimer: although we formally refer to whole-genome chromosome capture data as Hi-C, we will mostly work with Micro-C here.

To start, follow the instructions in What_we_see_in_Hi-C_8 July 2024 notebook.

Author: Aleksandra Galitsyna, based on the materials from Open2C and 4DN communities.