diff --git a/hw/ip_templates/flash_ctrl/data/flash_ctrl_sec_cm_testplan.hjson b/hw/ip_templates/flash_ctrl/data/flash_ctrl_sec_cm_testplan.hjson
index f02c3def9e273..d433474be5984 100644
--- a/hw/ip_templates/flash_ctrl/data/flash_ctrl_sec_cm_testplan.hjson
+++ b/hw/ip_templates/flash_ctrl/data/flash_ctrl_sec_cm_testplan.hjson
@@ -160,6 +160,16 @@
       stage: V2S
       tests: ["flash_ctrl_rd_intg", "flash_ctrl_access_after_disable"]
     }
+    {
+      name: sec_cm_mem_addr_infection
+      desc: '''Verify the countermeasure(s) MEM.ADDR_INFECTION.
+      Send a flash request from the host, inject a fault into the address inside
+      the flash_phy_rd module, and check that we receive the expected TL-UL
+      integrity error.
+      '''
+      stage: V2S
+      tests: ["flash_ctrl_host_addr_infection"]
+    }
     {
       name: sec_cm_mem_disable_config_mubi
       desc: "Verify the countermeasure(s) MEM_DISABLE.CONFIG.MUBI."
diff --git a/hw/ip_templates/flash_ctrl/dv/env/flash_ctrl_env.core b/hw/ip_templates/flash_ctrl/dv/env/flash_ctrl_env.core
index 884ca73a5b46c..735c3fb1f3aba 100644
--- a/hw/ip_templates/flash_ctrl/dv/env/flash_ctrl_env.core
+++ b/hw/ip_templates/flash_ctrl/dv/env/flash_ctrl_env.core
@@ -79,6 +79,7 @@ filesets:
       - seq_lib/flash_ctrl_oversize_error_vseq.sv: {is_include_file: true}
       - seq_lib/flash_ctrl_connect_vseq.sv: {is_include_file: true}
       - seq_lib/flash_ctrl_disable_vseq.sv: {is_include_file: true}
+      - seq_lib/flash_ctrl_host_addr_infection_vseq.sv: {is_include_file: true}
       - seq_lib/flash_ctrl_rd_path_intg_vseq.sv: {is_include_file: true}
       - seq_lib/flash_ctrl_wr_path_intg_vseq.sv: {is_include_file: true}
       - seq_lib/flash_ctrl_info_part_access_vseq.sv: {is_include_file: true}
diff --git a/hw/ip_templates/flash_ctrl/dv/env/seq_lib/flash_ctrl_host_addr_infection_vseq.sv b/hw/ip_templates/flash_ctrl/dv/env/seq_lib/flash_ctrl_host_addr_infection_vseq.sv
new file mode 100644
index 0000000000000..b23f3bdb002b5
--- /dev/null
+++ b/hw/ip_templates/flash_ctrl/dv/env/seq_lib/flash_ctrl_host_addr_infection_vseq.sv
@@ -0,0 +1,79 @@
+// Copyright lowRISC contributors (OpenTitan project).
+// Licensed under the Apache License, Version 2.0, see LICENSE for details.
+// SPDX-License-Identifier: Apache-2.0
+
+// This sequence issues a read to the flash controller. Inside the flash controller
+// a fault is injected into the address. The goal of this sequence is to check,
+// whether the data XOR address infection triggers a data integrity violation.
+class flash_ctrl_host_addr_infection_vseq extends flash_ctrl_legacy_base_vseq;
+  `uvm_object_utils(flash_ctrl_host_addr_infection_vseq)
+  `uvm_object_new
+
+  task body();
+    string path1, path2;
+    int    state_timeout_ns = 100000; // 100us
+
+    flash_op_t host;
+    bit [TL_AW-1:0] tl_addr;
+    bit [7:0]       addr_glitched;
+    bit             saw_err, completed;
+    data_4s_t rdata;
+
+    flash_otf_region_cfg(.scr_mode(OTFCfgTrue), .ecc_mode(OTFCfgTrue));
+    cfg.clk_rst_vif.wait_clks(10);
+
+    cfg.scb_h.expected_alert["fatal_err"].expected = 1;
+    cfg.scb_h.expected_alert["fatal_err"].max_delay = 2000;
+    cfg.scb_h.exp_alert_contd["fatal_err"] = 10000;
+
+    // We expect that the TL-UL integrity check fails because address used for
+    // the access gets manipulated and the data XOR address mechanism infects the
+    // data, resulting in an integrity error.
+    cfg.scb_h.exp_tl_rsp_intg_err = 1;
+
+    // Generate random address for the read access.
+    tl_addr[OTFBankId] = $urandom_range(0, 1);
+    tl_addr[OTFHostId-2:2] = $urandom();
+    tl_addr[1:0] = 'h0;
+    `uvm_info(`gfn, $sformatf("Original TL-UL address is 'h%0x", tl_addr), UVM_LOW)
+
+    // Flip bits in address before the data XOR address infection is done.
+    path1 = "tb.dut.u_eflash.gen_flash_cores[0].u_core.u_rd.addr_xor_muxed[8:1]";
+    path2 = "tb.dut.u_eflash.gen_flash_cores[1].u_core.u_rd.addr_xor_muxed[8:1]";
+    addr_glitched = tl_addr[8:1] ^ (1 << $urandom_range(0, 7));
+    `uvm_info(`gfn, $sformatf("Forcing %s to value 'h%0x", path1, addr_glitched), UVM_LOW)
+    `uvm_info(`gfn, $sformatf("Forcing %s to value 'h%0x", path2, addr_glitched), UVM_LOW)
+    `DV_CHECK(uvm_hdl_force(path1, addr_glitched))
+    `DV_CHECK(uvm_hdl_force(path2, addr_glitched))
+
+    // Perform the memory access.
+    tl_access_w_abort(.addr(tl_addr), .write(1'b0), .completed(completed),
+                      .saw_err(saw_err),
+                      .tl_access_timeout_ns(cfg.seq_cfg.erase_timeout_ns),
+                      .data(rdata), .check_rsp(0), .blocking(1),
+                      .tl_sequencer_h(p_sequencer.tl_sequencer_hs[cfg.flash_ral_name]));
+
+    csr_utils_pkg::wait_no_outstanding_access();
+
+    `uvm_info(`gfn, "Wait until all drain", UVM_LOW)
+    cfg.clk_rst_vif.wait_clks(100);
+    `DV_CHECK(uvm_hdl_release(path1))
+    `DV_CHECK(uvm_hdl_release(path2))
+
+    // reset for the next round
+    cfg.seq_cfg.disable_flash_init = 1;
+    cfg.seq_cfg.en_init_keys_seeds = 0;
+    apply_reset();
+    csr_wr(.ptr(ral.init), .value(1));
+    `uvm_info("Test","OTP",UVM_LOW)
+    otp_model();
+    `DV_SPINWAIT(wait(cfg.flash_ctrl_vif.rd_buf_en == 1);,
+                 "Timed out waiting for rd_buf_en",
+                 state_timeout_ns)
+    cfg.clk_rst_vif.wait_clks(10);
+
+    // disable tlul_err_cnt check
+    cfg.tlul_core_obs_cnt = cfg.tlul_core_exp_cnt;
+  endtask
+
+endclass
diff --git a/hw/ip_templates/flash_ctrl/dv/env/seq_lib/flash_ctrl_vseq_list.sv b/hw/ip_templates/flash_ctrl/dv/env/seq_lib/flash_ctrl_vseq_list.sv
index 72edfe1634691..39e506743fa11 100644
--- a/hw/ip_templates/flash_ctrl/dv/env/seq_lib/flash_ctrl_vseq_list.sv
+++ b/hw/ip_templates/flash_ctrl/dv/env/seq_lib/flash_ctrl_vseq_list.sv
@@ -48,6 +48,7 @@
 `include "flash_ctrl_oversize_error_vseq.sv"
 `include "flash_ctrl_connect_vseq.sv"
 `include "flash_ctrl_disable_vseq.sv"
+`include "flash_ctrl_host_addr_infection_vseq.sv"
 `include "flash_ctrl_rd_path_intg_vseq.sv"
 `include "flash_ctrl_wr_path_intg_vseq.sv"
 `include "flash_ctrl_info_part_access_vseq.sv"
diff --git a/hw/ip_templates/flash_ctrl/dv/flash_ctrl_base_sim_cfg.hjson b/hw/ip_templates/flash_ctrl/dv/flash_ctrl_base_sim_cfg.hjson
index bf335ac69db27..42ed3a9d45673 100644
--- a/hw/ip_templates/flash_ctrl/dv/flash_ctrl_base_sim_cfg.hjson
+++ b/hw/ip_templates/flash_ctrl/dv/flash_ctrl_base_sim_cfg.hjson
@@ -467,6 +467,13 @@
                  "+ecc_mode=1"]
       reseed: 1
     }
+    {
+      name: flash_ctrl_host_addr_infection
+      uvm_test_seq: flash_ctrl_host_addr_infection_vseq
+      run_opts: ["+scb_otf_en=1", "+ecc_mode=1",
+                 "+otf_num_hr=100", "+en_always_read=1"]
+      reseed: 3
+    }
  ]
 
   // List of regressions.
diff --git a/hw/top_earlgrey/ip_autogen/flash_ctrl/data/flash_ctrl_sec_cm_testplan.hjson b/hw/top_earlgrey/ip_autogen/flash_ctrl/data/flash_ctrl_sec_cm_testplan.hjson
index f02c3def9e273..d433474be5984 100644
--- a/hw/top_earlgrey/ip_autogen/flash_ctrl/data/flash_ctrl_sec_cm_testplan.hjson
+++ b/hw/top_earlgrey/ip_autogen/flash_ctrl/data/flash_ctrl_sec_cm_testplan.hjson
@@ -160,6 +160,16 @@
       stage: V2S
       tests: ["flash_ctrl_rd_intg", "flash_ctrl_access_after_disable"]
     }
+    {
+      name: sec_cm_mem_addr_infection
+      desc: '''Verify the countermeasure(s) MEM.ADDR_INFECTION.
+      Send a flash request from the host, inject a fault into the address inside
+      the flash_phy_rd module, and check that we receive the expected TL-UL
+      integrity error.
+      '''
+      stage: V2S
+      tests: ["flash_ctrl_host_addr_infection"]
+    }
     {
       name: sec_cm_mem_disable_config_mubi
       desc: "Verify the countermeasure(s) MEM_DISABLE.CONFIG.MUBI."
diff --git a/hw/top_earlgrey/ip_autogen/flash_ctrl/dv/env/flash_ctrl_env.core b/hw/top_earlgrey/ip_autogen/flash_ctrl/dv/env/flash_ctrl_env.core
index 884ca73a5b46c..735c3fb1f3aba 100644
--- a/hw/top_earlgrey/ip_autogen/flash_ctrl/dv/env/flash_ctrl_env.core
+++ b/hw/top_earlgrey/ip_autogen/flash_ctrl/dv/env/flash_ctrl_env.core
@@ -79,6 +79,7 @@ filesets:
       - seq_lib/flash_ctrl_oversize_error_vseq.sv: {is_include_file: true}
       - seq_lib/flash_ctrl_connect_vseq.sv: {is_include_file: true}
       - seq_lib/flash_ctrl_disable_vseq.sv: {is_include_file: true}
+      - seq_lib/flash_ctrl_host_addr_infection_vseq.sv: {is_include_file: true}
       - seq_lib/flash_ctrl_rd_path_intg_vseq.sv: {is_include_file: true}
       - seq_lib/flash_ctrl_wr_path_intg_vseq.sv: {is_include_file: true}
       - seq_lib/flash_ctrl_info_part_access_vseq.sv: {is_include_file: true}
diff --git a/hw/top_earlgrey/ip_autogen/flash_ctrl/dv/env/seq_lib/flash_ctrl_host_addr_infection_vseq.sv b/hw/top_earlgrey/ip_autogen/flash_ctrl/dv/env/seq_lib/flash_ctrl_host_addr_infection_vseq.sv
new file mode 100644
index 0000000000000..b23f3bdb002b5
--- /dev/null
+++ b/hw/top_earlgrey/ip_autogen/flash_ctrl/dv/env/seq_lib/flash_ctrl_host_addr_infection_vseq.sv
@@ -0,0 +1,79 @@
+// Copyright lowRISC contributors (OpenTitan project).
+// Licensed under the Apache License, Version 2.0, see LICENSE for details.
+// SPDX-License-Identifier: Apache-2.0
+
+// This sequence issues a read to the flash controller. Inside the flash controller
+// a fault is injected into the address. The goal of this sequence is to check,
+// whether the data XOR address infection triggers a data integrity violation.
+class flash_ctrl_host_addr_infection_vseq extends flash_ctrl_legacy_base_vseq;
+  `uvm_object_utils(flash_ctrl_host_addr_infection_vseq)
+  `uvm_object_new
+
+  task body();
+    string path1, path2;
+    int    state_timeout_ns = 100000; // 100us
+
+    flash_op_t host;
+    bit [TL_AW-1:0] tl_addr;
+    bit [7:0]       addr_glitched;
+    bit             saw_err, completed;
+    data_4s_t rdata;
+
+    flash_otf_region_cfg(.scr_mode(OTFCfgTrue), .ecc_mode(OTFCfgTrue));
+    cfg.clk_rst_vif.wait_clks(10);
+
+    cfg.scb_h.expected_alert["fatal_err"].expected = 1;
+    cfg.scb_h.expected_alert["fatal_err"].max_delay = 2000;
+    cfg.scb_h.exp_alert_contd["fatal_err"] = 10000;
+
+    // We expect that the TL-UL integrity check fails because address used for
+    // the access gets manipulated and the data XOR address mechanism infects the
+    // data, resulting in an integrity error.
+    cfg.scb_h.exp_tl_rsp_intg_err = 1;
+
+    // Generate random address for the read access.
+    tl_addr[OTFBankId] = $urandom_range(0, 1);
+    tl_addr[OTFHostId-2:2] = $urandom();
+    tl_addr[1:0] = 'h0;
+    `uvm_info(`gfn, $sformatf("Original TL-UL address is 'h%0x", tl_addr), UVM_LOW)
+
+    // Flip bits in address before the data XOR address infection is done.
+    path1 = "tb.dut.u_eflash.gen_flash_cores[0].u_core.u_rd.addr_xor_muxed[8:1]";
+    path2 = "tb.dut.u_eflash.gen_flash_cores[1].u_core.u_rd.addr_xor_muxed[8:1]";
+    addr_glitched = tl_addr[8:1] ^ (1 << $urandom_range(0, 7));
+    `uvm_info(`gfn, $sformatf("Forcing %s to value 'h%0x", path1, addr_glitched), UVM_LOW)
+    `uvm_info(`gfn, $sformatf("Forcing %s to value 'h%0x", path2, addr_glitched), UVM_LOW)
+    `DV_CHECK(uvm_hdl_force(path1, addr_glitched))
+    `DV_CHECK(uvm_hdl_force(path2, addr_glitched))
+
+    // Perform the memory access.
+    tl_access_w_abort(.addr(tl_addr), .write(1'b0), .completed(completed),
+                      .saw_err(saw_err),
+                      .tl_access_timeout_ns(cfg.seq_cfg.erase_timeout_ns),
+                      .data(rdata), .check_rsp(0), .blocking(1),
+                      .tl_sequencer_h(p_sequencer.tl_sequencer_hs[cfg.flash_ral_name]));
+
+    csr_utils_pkg::wait_no_outstanding_access();
+
+    `uvm_info(`gfn, "Wait until all drain", UVM_LOW)
+    cfg.clk_rst_vif.wait_clks(100);
+    `DV_CHECK(uvm_hdl_release(path1))
+    `DV_CHECK(uvm_hdl_release(path2))
+
+    // reset for the next round
+    cfg.seq_cfg.disable_flash_init = 1;
+    cfg.seq_cfg.en_init_keys_seeds = 0;
+    apply_reset();
+    csr_wr(.ptr(ral.init), .value(1));
+    `uvm_info("Test","OTP",UVM_LOW)
+    otp_model();
+    `DV_SPINWAIT(wait(cfg.flash_ctrl_vif.rd_buf_en == 1);,
+                 "Timed out waiting for rd_buf_en",
+                 state_timeout_ns)
+    cfg.clk_rst_vif.wait_clks(10);
+
+    // disable tlul_err_cnt check
+    cfg.tlul_core_obs_cnt = cfg.tlul_core_exp_cnt;
+  endtask
+
+endclass
diff --git a/hw/top_earlgrey/ip_autogen/flash_ctrl/dv/env/seq_lib/flash_ctrl_vseq_list.sv b/hw/top_earlgrey/ip_autogen/flash_ctrl/dv/env/seq_lib/flash_ctrl_vseq_list.sv
index 72edfe1634691..39e506743fa11 100644
--- a/hw/top_earlgrey/ip_autogen/flash_ctrl/dv/env/seq_lib/flash_ctrl_vseq_list.sv
+++ b/hw/top_earlgrey/ip_autogen/flash_ctrl/dv/env/seq_lib/flash_ctrl_vseq_list.sv
@@ -48,6 +48,7 @@
 `include "flash_ctrl_oversize_error_vseq.sv"
 `include "flash_ctrl_connect_vseq.sv"
 `include "flash_ctrl_disable_vseq.sv"
+`include "flash_ctrl_host_addr_infection_vseq.sv"
 `include "flash_ctrl_rd_path_intg_vseq.sv"
 `include "flash_ctrl_wr_path_intg_vseq.sv"
 `include "flash_ctrl_info_part_access_vseq.sv"
diff --git a/hw/top_earlgrey/ip_autogen/flash_ctrl/dv/flash_ctrl_base_sim_cfg.hjson b/hw/top_earlgrey/ip_autogen/flash_ctrl/dv/flash_ctrl_base_sim_cfg.hjson
index bf335ac69db27..42ed3a9d45673 100644
--- a/hw/top_earlgrey/ip_autogen/flash_ctrl/dv/flash_ctrl_base_sim_cfg.hjson
+++ b/hw/top_earlgrey/ip_autogen/flash_ctrl/dv/flash_ctrl_base_sim_cfg.hjson
@@ -467,6 +467,13 @@
                  "+ecc_mode=1"]
       reseed: 1
     }
+    {
+      name: flash_ctrl_host_addr_infection
+      uvm_test_seq: flash_ctrl_host_addr_infection_vseq
+      run_opts: ["+scb_otf_en=1", "+ecc_mode=1",
+                 "+otf_num_hr=100", "+en_always_read=1"]
+      reseed: 3
+    }
  ]
 
   // List of regressions.