diff --git a/docs/site/Interceptors.md b/docs/site/Interceptors.md
index 589f44d304a7..1ce48b43baad 100644
--- a/docs/site/Interceptors.md
+++ b/docs/site/Interceptors.md
@@ -586,6 +586,32 @@ The implementation of an interceptor can check `source` to decide if its logic
 should apply. For example, a global interceptor that provides caching for REST
 APIs should only run if the source is from a REST Route.
 
+A global interceptor can also be tagged with
+`ContextTags.GLOBAL_INTERCEPTOR_SOURCE` using a value of string or string array
+to indicate if it should be applied to source types of invocations. If the tag
+is not present, the interceptor applies to invocations of any source type. For
+example:
+
+```ts
+ctx
+  .bind('globalInterceptors.authInterceptor')
+  .to(authInterceptor)
+  .apply(asGlobalInterceptor('auth'))
+  // Do not apply for `proxy` source type
+  .tag({[ContextTags.GLOBAL_INTERCEPTOR_SOURCE]: 'route'});
+```
+
+The tag can also be declared for the provider class.
+
+```ts
+@globalInterceptor('log', {
+  tags: {[ContextTags.GLOBAL_INTERCEPTOR_SOURCE]: ['proxy']},
+})
+export class LogInterceptor implements Provider<Interceptor> {
+  // ...
+}
+```
+
 ### Logic around `next`
 
 An interceptor will receive the `next` parameter, which is a function to execute
diff --git a/packages/context/src/__tests__/unit/interceptor.unit.ts b/packages/context/src/__tests__/unit/interceptor.unit.ts
index 896ff608376b..a44bf62910ff 100644
--- a/packages/context/src/__tests__/unit/interceptor.unit.ts
+++ b/packages/context/src/__tests__/unit/interceptor.unit.ts
@@ -15,6 +15,7 @@ import {
   InterceptedInvocationContext,
   Interceptor,
   InterceptorOrKey,
+  InvocationSource,
   mergeInterceptors,
   Provider,
 } from '../..';
@@ -190,6 +191,68 @@ describe('globalInterceptors', () => {
     });
   });
 
+  it('includes interceptors that match the source type', () => {
+    ctx
+      .bind('globalInterceptors.authInterceptor')
+      .to(authInterceptor)
+      .apply(asGlobalInterceptor('auth'))
+      // Allows `route` source type explicitly
+      .tag({[ContextTags.GLOBAL_INTERCEPTOR_SOURCE]: 'route'});
+
+    ctx
+      .bind('globalInterceptors.logInterceptor')
+      .to(logInterceptor)
+      .apply(asGlobalInterceptor('log'));
+    // No source type is tagged - always apply
+
+    const invocationCtx = givenInvocationContext('route');
+
+    const keys = invocationCtx.getGlobalInterceptorBindingKeys();
+    expect(keys).to.eql([
+      'globalInterceptors.authInterceptor',
+      'globalInterceptors.logInterceptor',
+    ]);
+  });
+
+  it('excludes interceptors that do not match the source type', () => {
+    ctx
+      .bind('globalInterceptors.authInterceptor')
+      .to(authInterceptor)
+      .apply(asGlobalInterceptor('auth'))
+      // Do not apply for `proxy` source type
+      .tag({[ContextTags.GLOBAL_INTERCEPTOR_SOURCE]: 'route'});
+
+    ctx
+      .bind('globalInterceptors.logInterceptor')
+      .to(logInterceptor)
+      .apply(asGlobalInterceptor('log'));
+
+    const invocationCtx = givenInvocationContext('proxy');
+
+    const keys = invocationCtx.getGlobalInterceptorBindingKeys();
+    expect(keys).to.eql(['globalInterceptors.logInterceptor']);
+  });
+
+  it('excludes interceptors that do not match the source type - with array', () => {
+    ctx
+      .bind('globalInterceptors.authInterceptor')
+      .to(authInterceptor)
+      .apply(asGlobalInterceptor('auth'))
+      // Do not apply for `proxy` source type
+      .tag({[ContextTags.GLOBAL_INTERCEPTOR_SOURCE]: 'route'});
+
+    ctx
+      .bind('globalInterceptors.logInterceptor')
+      .to(logInterceptor)
+      .apply(asGlobalInterceptor('log'))
+      .tag({[ContextTags.GLOBAL_INTERCEPTOR_SOURCE]: ['route', 'proxy']});
+
+    const invocationCtx = givenInvocationContext('proxy');
+
+    const keys = invocationCtx.getGlobalInterceptorBindingKeys();
+    expect(keys).to.eql(['globalInterceptors.logInterceptor']);
+  });
+
   class MyController {
     greet(name: string) {
       return `Hello, ${name}`;
@@ -200,9 +263,20 @@ describe('globalInterceptors', () => {
     ctx = new Context();
   }
 
-  function givenInvocationContext() {
-    return new InterceptedInvocationContext(ctx, new MyController(), 'greet', [
-      'John',
-    ]);
+  function givenInvocationContext(source?: string) {
+    let invocationSource: InvocationSource<string> | undefined = undefined;
+    if (source != null) {
+      invocationSource = {
+        type: source,
+        value: source,
+      };
+    }
+    return new InterceptedInvocationContext(
+      ctx,
+      new MyController(),
+      'greet',
+      ['John'],
+      invocationSource,
+    );
   }
 });
diff --git a/packages/context/src/interceptor.ts b/packages/context/src/interceptor.ts
index 94f37dec4a48..aa5fc36b49a8 100644
--- a/packages/context/src/interceptor.ts
+++ b/packages/context/src/interceptor.ts
@@ -48,7 +48,10 @@ export class InterceptedInvocationContext extends InvocationContext {
    */
   getGlobalInterceptorBindingKeys(): string[] {
     const bindings: Readonly<Binding<Interceptor>>[] = this.find(
-      filterByTag(ContextTags.GLOBAL_INTERCEPTOR),
+      binding =>
+        filterByTag(ContextTags.GLOBAL_INTERCEPTOR)(binding) &&
+        // Only include interceptors that match the source type of the invocation
+        this.applicableTo(binding),
     );
     this.sortGlobalInterceptorBindings(bindings);
     const keys = bindings.map(b => b.key);
@@ -56,6 +59,27 @@ export class InterceptedInvocationContext extends InvocationContext {
     return keys;
   }
 
+  /**
+   * Check if the binding for a global interceptor matches the source type
+   * of the invocation
+   * @param binding - Binding
+   */
+  private applicableTo(binding: Readonly<Binding<unknown>>) {
+    const sourceType = this.source?.type;
+    // Unknown source type, always apply
+    if (sourceType == null) return true;
+    const allowedSource: string | string[] =
+      binding.tagMap[ContextTags.GLOBAL_INTERCEPTOR_SOURCE];
+    return (
+      // No tag, always apply
+      allowedSource == null ||
+      // source matched
+      allowedSource === sourceType ||
+      // source included in the string[]
+      (Array.isArray(allowedSource) && allowedSource.includes(sourceType))
+    );
+  }
+
   /**
    * Sort global interceptor bindings by `globalInterceptorGroup` tags
    * @param bindings - An array of global interceptor bindings
diff --git a/packages/context/src/keys.ts b/packages/context/src/keys.ts
index 7e0e014c34b3..3ded8c77aae1 100644
--- a/packages/context/src/keys.ts
+++ b/packages/context/src/keys.ts
@@ -40,6 +40,13 @@ export namespace ContextTags {
    */
   export const GLOBAL_INTERCEPTOR = 'globalInterceptor';
 
+  /**
+   * Binding tag for global interceptors to specify sources of invocations that
+   * the interceptor should apply. The tag value can be a string or string[], such
+   * as `'route'` or `['route', 'proxy']`.
+   */
+  export const GLOBAL_INTERCEPTOR_SOURCE = 'globalInterceptorSource';
+
   /**
    * Binding tag for group name of global interceptors
    */