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The output of RegParallel is a data.table. Can it be the model fit to allow contrasts? Let's say there is a data that has multiple patients and each patient sample has multiple cell types. It doesn't seem feasible to extract cell type markers by fitting a full model ~cellType + patientID, followed by computing contrasts such as epithelial-(Tcell + Bcell + NKcell)/3 which limma can do.
The text was updated successfully, but these errors were encountered:
The output of
RegParallel
is adata.table
. Can it be the model fit to allow contrasts? Let's say there is a data that has multiple patients and each patient sample has multiple cell types. It doesn't seem feasible to extract cell type markers by fitting a full model~cellType + patientID
, followed by computing contrasts such asepithelial-(Tcell + Bcell + NKcell)/3
which limma can do.The text was updated successfully, but these errors were encountered: