diff --git a/go.mod b/go.mod
index d5a30ea70d..0faf225636 100644
--- a/go.mod
+++ b/go.mod
@@ -62,7 +62,7 @@ require (
 	github.com/prometheus/common v0.45.1-0.20231122191551-832cd6e99f99
 	github.com/prometheus/exporter-toolkit v0.10.0
 	// Prometheus maps version 2.x.y to tags v0.x.y.
-	github.com/prometheus/prometheus v0.48.1-0.20240115084306-17920623e7cd
+	github.com/prometheus/prometheus v0.49.0-rc.2.0.20240116085416-72a8f1084b29
 	github.com/sony/gobreaker v0.5.0
 	github.com/stretchr/testify v1.8.4
 	github.com/thanos-io/objstore v0.0.0-20231112185854-37752ee64d98
diff --git a/go.sum b/go.sum
index 10003653f5..200b7832f1 100644
--- a/go.sum
+++ b/go.sum
@@ -894,8 +894,8 @@ github.com/prometheus/procfs v0.7.3/go.mod h1:cz+aTbrPOrUb4q7XlbU9ygM+/jj0fzG6c1
 github.com/prometheus/procfs v0.8.0/go.mod h1:z7EfXMXOkbkqb9IINtpCn86r/to3BnA0uaxHdg830/4=
 github.com/prometheus/procfs v0.12.0 h1:jluTpSng7V9hY0O2R9DzzJHYb2xULk9VTR1V1R/k6Bo=
 github.com/prometheus/procfs v0.12.0/go.mod h1:pcuDEFsWDnvcgNzo4EEweacyhjeA9Zk3cnaOZAZEfOo=
-github.com/prometheus/prometheus v0.48.1-0.20240115084306-17920623e7cd h1:qq+8W4nYaar4QxY6JtYYVfUfO4AVNQcJ53Jaz3UZCMU=
-github.com/prometheus/prometheus v0.48.1-0.20240115084306-17920623e7cd/go.mod h1:NCkyb7Sg5TsJxi6Hx9rCcAXZ2E1Bu7x0dYOQ0jLTfDU=
+github.com/prometheus/prometheus v0.49.0-rc.2.0.20240116085416-72a8f1084b29 h1:poqfIBU1Rt6K1lA0IxizRrN/NoOY1bVtTmrQT9HsmOg=
+github.com/prometheus/prometheus v0.49.0-rc.2.0.20240116085416-72a8f1084b29/go.mod h1:NCkyb7Sg5TsJxi6Hx9rCcAXZ2E1Bu7x0dYOQ0jLTfDU=
 github.com/rcrowley/go-metrics v0.0.0-20181016184325-3113b8401b8a/go.mod h1:bCqnVzQkZxMG4s8nGwiZ5l3QUCyqpo9Y+/ZMZ9VjZe4=
 github.com/redis/rueidis v1.0.14-go1.18 h1:dGir5z8w8X1ex7JWO/Zx2FMBrZgQ8Yjm+lw9fPLSNGw=
 github.com/redis/rueidis v1.0.14-go1.18/go.mod h1:HGekzV3HbmzFmRK6j0xic8Z9119+ECoGMjeN1TV1NYU=
diff --git a/pkg/receive/multitsdb.go b/pkg/receive/multitsdb.go
index 3583ce8f3a..754b2ad6e7 100644
--- a/pkg/receive/multitsdb.go
+++ b/pkg/receive/multitsdb.go
@@ -582,6 +582,12 @@ func (t *MultiTSDB) startTSDB(logger log.Logger, tenantID string, tenant *tenant
 
 	level.Info(logger).Log("msg", "opening TSDB")
 	opts := *t.tsdbOpts
+
+	// NOTE(GiedriusS): always set to false to properly handle OOO samples - OOO samples are written into the WBL
+	// which gets later converted into a block. Without setting this flag to false, the block would get compacted
+	// into other ones. This presents a race between compaction and the shipper (if it is configured to upload compacted blocks).
+	// Hence, avoid this situation by disabling overlapping compaction. Vertical compaction must be enabled on the compactor.
+	opts.EnableOverlappingCompaction = false
 	s, err := tsdb.Open(
 		dataDir,
 		logger,