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Review annotations to GO:0000717 nucleotide-excision repair, DNA duplex unwinding and related terms #5540

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raymond91125 opened this issue Nov 19, 2024 · 6 comments
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annotation review direct_ann_to_list_of_terms Direct annotations to list of GO terms

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@raymond91125
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raymond91125 commented Nov 19, 2024

Dear all,

The proposal has been made to obsolete BP
GO:0000717 nucleotide-excision repair, DNA duplex unwinding
GO:0044806 G-quadruplex DNA unwinding
GO:1905466 negative regulation of G-quadruplex DNA unwinding
GO:1905467 positive regulation of G-quadruplex DNA unwinding
GO:1905465 regulation of G-quadruplex DNA unwinding
GO:0036292 DNA rewinding
For they are MFs.
see geneontology/go-ontology#29153

Experimental annotations that need to be reviewed are here:
https://docs.google.com/spreadsheets/d/1erB5WI0Z8FBHCTb3oCat92fDijtsb7u7O9-RV3dPHJE/edit?gid=0#gid=0

Impacted groups:
ComplexPortal 3
UniProt 12
FlyBase 3
TAIR 1
BHF-UCL 8 -done
PomBase 4
SGD 5

** Group contacts: https://github.com/geneontology/go-site/blob/master/metadata/group-contacts.csv

Mappings that need to be reviewed: (InterPro2GO, UniProt-Keywords, UniRule)
None

Thanks.

@ValWood
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ValWood commented Nov 21, 2024

Hi @raymond91125 it seems like we need a term for "guanine quadruplex resolver helicase" (both DNA and RNA)
this particular activity seems to be a major activity of specific helicases including the ReqQ helicases (WRN,BLM ). Pif1 family, Fanconi Anemia Helicase J, DHX36 (RHAU, G4R1) A highly specialized RNA and DNA helicase with robust G4-resolving activity, Dna2, Subunits of the TFIIH transcription/repair complex, these helicases can unwind G4 structures in the context of transcription-coupled repair. and others.

This is useful functional context to retain. I can't find another specific term to replace GO:0044806 G-quadruplex DNA unwinding

@RLovering
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I agree with Val, I had deleted our GO:0044806 G-quadruplex DNA unwinding annotations although I had sometimes applied the parent term GO:0032392 DNA geometric change

@raymond91125
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Hi @raymond91125 it seems like we need a term for "guanine quadruplex resolver helicase" (both DNA and RNA) this particular activity seems to be a major activity of specific helicases including the ReqQ helicases (WRN,BLM ). Pif1 family, Fanconi Anemia Helicase J, DHX36 (RHAU, G4R1) A highly specialized RNA and DNA helicase with robust G4-resolving activity, Dna2, Subunits of the TFIIH transcription/repair complex, these helicases can unwind G4 structures in the context of transcription-coupled repair. and others.

This is useful functional context to retain. I can't find another specific term to replace GO:0044806 G-quadruplex DNA unwinding

@ValWood Would you make a new term request, please?

@tberardini
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TAIR done.

@tberardini tberardini removed their assignment Nov 27, 2024
@hattrill
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FB done.

@hattrill hattrill removed their assignment Nov 29, 2024
@Antonialock
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UniProt done

@Antonialock Antonialock removed their assignment Nov 29, 2024
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