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Data preparation

Datasets download

Here are all published dataset used in our paper.

Index Paper Species Tissue Technology Resolution Cells/Spots Genes Download
1 Chen et al. Mouse Whole embryo Stereo-seq 0.2μm 5000-100,000 >20,000 website
2 Lohoff et al. Mouse Whole embryo seqFISH subcellular ~10,000 351 website
3 Deng et al. Mouse Whole embryo spatial-ATAC-seq 20μm 2099 >20,000 website
4 Jeffrey et al. Mouse Brain(hypothalamic preoptic) MERFISH subcellular ~6,500 151 website
5 Kristen et al. Human Brain(dorsolateral prefrontal cortex, DLPFC) 10x Visium 50μm ~3500 >20,000 website
6 Amanda et al. Human Breast cancer 10x Visium 50μm ~3500 >20,000 website
7 Amanda et al. Human Breast cancer 10x Xenium subcellular > 140,000 311 website

Data preprocessing

We do some necessary pre-processing on some of them, you can repeat them by:

  1. For Stereo-seq, please follow the ./Stereo_process.ipynb to do pre-processing.
  2. For spatial-ATAC-seq, we filter out the spots which not locate in tissue as authors did.