diff --git a/ChangeLog.md b/ChangeLog.md
index 785f80d53087d..687277411713a 100644
--- a/ChangeLog.md
+++ b/ChangeLog.md
@@ -48,6 +48,9 @@ See docs/process.md for more on how version tagging works.
   `--post-js` files will now be delayed until after module creation and after
   `main` runs.  This matches the existing behaviour when using sync instantation
   (`-sWASM_ASYNC_COMPILATION=0`) but is an observable difference. (#23157)
+- The `POLYFILL_OLD_MATH_FUNCTIONS` setting was removed.  The browser versions
+  that require these polyfills are no longer supported by emscripten so the
+  polyfills should never be needed. (#23262)
 
 3.1.74 - 12/14/24
 -----------------
diff --git a/src/preamble.js b/src/preamble.js
index 7ba3754e88051..6db7ff58b51a1 100644
--- a/src/preamble.js
+++ b/src/preamble.js
@@ -324,8 +324,6 @@ function addOnPostRun(cb) {
   __ATPOSTRUN__.unshift(cb);
 }
 
-#include "runtime_math.js"
-
 // A counter of dependencies for calling run(). If we need to
 // do asynchronous work before running, increment this and
 // decrement it. Incrementing must happen in a place like
diff --git a/src/preamble_minimal.js b/src/preamble_minimal.js
index a49ca40962d44..ab83b52cc90b7 100644
--- a/src/preamble_minimal.js
+++ b/src/preamble_minimal.js
@@ -85,7 +85,6 @@ var runtimeExited = false;
 var runtimeInitialized = false;
 #endif
 
-#include "runtime_math.js"
 #include "memoryprofiler.js"
 #include "runtime_exceptions.js"
 #include "runtime_debug.js"
diff --git a/src/runtime_math.js b/src/runtime_math.js
deleted file mode 100644
index 999255167fae6..0000000000000
--- a/src/runtime_math.js
+++ /dev/null
@@ -1,53 +0,0 @@
-/**
- * @license
- * Copyright 2019 The Emscripten Authors
- * SPDX-License-Identifier: MIT
- */
-
-// https://developer.mozilla.org/en-US/docs/Web/JavaScript/Reference/Global_Objects/Math/imul
-#if POLYFILL_OLD_MATH_FUNCTIONS || MIN_CHROME_VERSION < 28 || MIN_FIREFOX_VERSION < 20 || MIN_SAFARI_VERSION < 90000 // || MIN_NODE_VERSION < 0.12
-// || MIN_NODE_VERSION < 0.12
-// check for imul support, and also for correctness ( https://bugs.webkit.org/show_bug.cgi?id=126345 )
-if (!Math.imul || Math.imul(0xffffffff, 5) !== -5) Math.imul = (a, b) => {
-  var ah  = a >>> 16;
-  var al = a & 0xffff;
-  var bh  = b >>> 16;
-  var bl = b & 0xffff;
-  return (al*bl + ((ah*bl + al*bh) << 16))|0;
-};
-#endif
-
-// https://developer.mozilla.org/en-US/docs/Web/JavaScript/Reference/Global_Objects/Math/fround
-#if POLYFILL_OLD_MATH_FUNCTIONS || MIN_CHROME_VERSION < 38 || MIN_FIREFOX_VERSION < 26 || MIN_SAFARI_VERSION < 80000 // || MIN_NODE_VERSION < 0.12
-if (!Math.fround) {
-  var froundBuffer = new Float32Array(1);
-  Math.fround = (x) => { froundBuffer[0] = x; return froundBuffer[0] };
-}
-#endif
-
-// https://developer.mozilla.org/en-US/docs/Web/JavaScript/Reference/Global_Objects/Math/clz32
-#if POLYFILL_OLD_MATH_FUNCTIONS || MIN_CHROME_VERSION < 38 || MIN_FIREFOX_VERSION < 31 // || MIN_NODE_VERSION < 0.12
-Math.clz32 ||= (x) => {
-  var n = 32;
-  var y = x >> 16; if (y) { n -= 16; x = y; }
-  y = x >> 8; if (y) { n -= 8; x = y; }
-  y = x >> 4; if (y) { n -= 4; x = y; }
-  y = x >> 2; if (y) { n -= 2; x = y; }
-  y = x >> 1; if (y) return n - 2;
-  return n - x;
-};
-#endif
-
-// https://developer.mozilla.org/en-US/docs/Web/JavaScript/Reference/Global_Objects/Math/trunc
-#if POLYFILL_OLD_MATH_FUNCTIONS || MIN_CHROME_VERSION < 38 || MIN_FIREFOX_VERSION < 25 || MIN_SAFARI_VERSION < 80000 // || MIN_NODE_VERSION < 0.12
-Math.trunc ||= (x) => {
-  return x < 0 ? Math.ceil(x) : Math.floor(x);
-};
-#endif
-
-#if ASSERTIONS
-assert(Math.imul, 'This browser does not support Math.imul(), build with LEGACY_VM_SUPPORT or POLYFILL_OLD_MATH_FUNCTIONS to add in a polyfill');
-assert(Math.fround, 'This browser does not support Math.fround(), build with LEGACY_VM_SUPPORT or POLYFILL_OLD_MATH_FUNCTIONS to add in a polyfill');
-assert(Math.clz32, 'This browser does not support Math.clz32(), build with LEGACY_VM_SUPPORT or POLYFILL_OLD_MATH_FUNCTIONS to add in a polyfill');
-assert(Math.trunc, 'This browser does not support Math.trunc(), build with LEGACY_VM_SUPPORT or POLYFILL_OLD_MATH_FUNCTIONS to add in a polyfill');
-#endif
diff --git a/test/test_other.py b/test/test_other.py
index 59ef936fcbaea..192325d1468f9 100644
--- a/test/test_other.py
+++ b/test/test_other.py
@@ -4908,20 +4908,6 @@ def test_precompiled_headers(self, suffix):
     output = self.run_js('a.out.js')
     self.assertContained('|5|', output)
 
-  def test_LEGACY_VM_SUPPORT(self):
-    # when modern features are lacking, we can polyfill them or at least warn
-    create_file('pre.js', 'Math.imul = undefined;')
-
-    def test(expected, opts):
-      print(opts)
-      self.run_process([EMCC, test_file('hello_world.c'), '--pre-js', 'pre.js'] + opts)
-      self.assertContained(expected, self.run_js('a.out.js', assert_returncode=0 if opts else NON_ZERO))
-
-    # when legacy is needed, we show an error indicating so
-    test('build with LEGACY_VM_SUPPORT', [])
-    # legacy + disabling wasm works
-    test('hello, world!', ['-sLEGACY_VM_SUPPORT', '-sWASM=0'])
-
   @crossplatform
   def test_on_abort(self):
     expected_output = 'Module.onAbort was called'
diff --git a/tools/link.py b/tools/link.py
index 6c3ca352ff6d7..0f7888ee30a61 100644
--- a/tools/link.py
+++ b/tools/link.py
@@ -1157,9 +1157,6 @@ def phase_linker_setup(options, state, newargs):  # noqa: C901, PLR0912, PLR0915
     if settings.MINIMAL_RUNTIME and options.oformat == OFormat.HTML and not settings.PTHREADS:
       settings.USE_READY_PROMISE = 0
 
-  if settings.WASM2JS and settings.LEGACY_VM_SUPPORT:
-    settings.POLYFILL_OLD_MATH_FUNCTIONS = 1
-
   check_browser_versions()
 
   if settings.MIN_NODE_VERSION >= 150000:
@@ -1202,10 +1199,6 @@ def phase_linker_setup(options, state, newargs):  # noqa: C901, PLR0912, PLR0915
     diagnostics.warning('transpile', '-sEXCEPTION_STACK_TRACES requires an engine that support ES6 classes.')
     settings.EXCEPTION_STACK_TRACES = 0
 
-  # Silently drop any individual backwards compatibility emulation flags that are known never to occur on browsers that support WebAssembly.
-  if not settings.WASM2JS:
-    settings.POLYFILL_OLD_MATH_FUNCTIONS = 0
-
   if settings.STB_IMAGE:
     state.append_link_flag('-lstb_image')
     settings.EXPORTED_FUNCTIONS += ['_stbi_load', '_stbi_load_from_memory', '_stbi_image_free']