diff --git a/easybuild/easyconfigs/s/Spectre/Spectre-0.2.1-foss-2023a.eb b/easybuild/easyconfigs/s/Spectre/Spectre-0.2.1-foss-2023a.eb
new file mode 100644
index 00000000000..a2a82a58532
--- /dev/null
+++ b/easybuild/easyconfigs/s/Spectre/Spectre-0.2.1-foss-2023a.eb
@@ -0,0 +1,31 @@
+easyblock = 'PythonPackage'
+
+name = 'Spectre'
+version = '0.2.1'
+
+homepage = 'https://github.com/fritzsedlazeck/Spectre'
+description = """Spectre is a long read copy number variation (CNV) caller. Spectre is designed to detect large CNVs
+(>100kb) in a couple of minutes depending on your hardware."""
+
+toolchain = {'name': 'foss', 'version': '2023a'}
+
+source_urls = ['https://pypi.org/packages/source/s/spectre-cnv/']
+sources = [{'download_filename': 'spectre_cnv-%(version)s.tar.gz', 'filename': SOURCE_TAR_GZ}]
+checksums = ['a5ab6487bdf239f4df0158632020d57be3cc78831e0fb1f41f27c5a79060cf5a']
+
+dependencies = [
+    ('Python', '3.11.3'),
+    ('SciPy-bundle', '2023.07'),
+    ('Pysam', '0.22.0'),
+    ('matplotlib', '3.7.2'),
+]
+
+use_pip = True
+download_dep_fail = True
+sanity_pip_check = True
+
+sanity_check_commands = [
+    "spectre --help",
+]
+
+moduleclass = 'bio'