diff --git a/lib/wasmbuild.generated.js b/lib/wasmbuild.generated.js
index 43578c6..14c04eb 100644
--- a/lib/wasmbuild.generated.js
+++ b/lib/wasmbuild.generated.js
@@ -295,7 +295,9 @@ class WasmBuildLoader {
     const isFile = url.protocol === "file:";
 
     // make file urls work in Node via dnt
-    const isNode = globalThis.process?.versions?.node != null;
+    const isNode = globalThis.Deno == null
+      && globalThis.process?.versions?.node != null
+      && globalThis.Buffer != null;
     if (isFile && typeof Deno !== "object") {
       throw new Error(
         "Loading local files are not supported in this environment",