You signed in with another tab or window. Reload to refresh your session.You signed out in another tab or window. Reload to refresh your session.You switched accounts on another tab or window. Reload to refresh your session.Dismiss alert
We have several metrics that could be used to indicate high vs lower-quality phenotype-locus associations. For example, the number of cases reported, pathogenic genotype frequency, etc.
Would it be useful to have some kind of field that indicates loci that should potentially be excluded from downstream analyses? I'm thinking in particular of DMD and POLG.
Also, a better way of flagging mendelian vs modifier loci?
Thanks to @fakedrtom for feedback on this
reacted with thumbs up emoji reacted with thumbs down emoji reacted with laugh emoji reacted with hooray emoji reacted with confused emoji reacted with heart emoji reacted with rocket emoji reacted with eyes emoji
-
We have several metrics that could be used to indicate high vs lower-quality phenotype-locus associations. For example, the number of cases reported, pathogenic genotype frequency, etc.
Would it be useful to have some kind of field that indicates loci that should potentially be excluded from downstream analyses? I'm thinking in particular of DMD and POLG.
Also, a better way of flagging mendelian vs modifier loci?
Thanks to @fakedrtom for feedback on this
Beta Was this translation helpful? Give feedback.
All reactions