diff --git a/.github/workflows/reusable-tests.yaml b/.github/workflows/reusable-tests.yaml
index 1c7d815a32..10e875a9b6 100644
--- a/.github/workflows/reusable-tests.yaml
+++ b/.github/workflows/reusable-tests.yaml
@@ -338,6 +338,9 @@ jobs:
     name: Test Anchor Init
     runs-on: ubuntu-latest
     timeout-minutes: 30
+    strategy:
+      matrix:
+        template: [mocha, jest, rust, mollusk]
     steps:
       - uses: actions/checkout@v3
       - uses: ./.github/actions/setup/
@@ -358,7 +361,7 @@ jobs:
           path: ~/.cargo/bin/
       - run: chmod +x ~/.cargo/bin/anchor
 
-      - run: cd "$(mktemp -d)" && anchor init hello-anchor && cd hello-anchor && yarn link @coral-xyz/anchor && yarn && anchor test && yarn lint:fix
+      - run: cd "$(mktemp -d)" && anchor init --test-template ${{ matrix.template }} hello-anchor-${{ matrix.template }} && cd hello-anchor-${{ matrix.template }} && yarn link @coral-xyz/anchor && yarn && anchor test && yarn lint:fix
       - uses: ./.github/actions/git-diff/
 
   test-programs:
diff --git a/CHANGELOG.md b/CHANGELOG.md
index 420ef71e7f..754731e34e 100644
--- a/CHANGELOG.md
+++ b/CHANGELOG.md
@@ -59,6 +59,7 @@ The minor version will be incremented upon a breaking change and the patch versi
 - avm: Add short alias for `install` and `list` commands ([#3326](https://github.com/coral-xyz/anchor/pull/3326)).
 - avm: Add Windows support for renaming anchor binary ([#3325](https://github.com/coral-xyz/anchor/pull/3325)).
 - cli: Add optional `package-manager` flag in `init` command to set package manager field in Anchor.toml ([#3328](https://github.com/coral-xyz/anchor/pull/3328)).
+- cli: Add test template for [Mollusk](https://github.com/buffalojoec/mollusk) ([#3352](https://github.com/coral-xyz/anchor/pull/3352)).
 
 ### Fixes
 
diff --git a/cli/src/lib.rs b/cli/src/lib.rs
index de9d569654..52b22d724d 100644
--- a/cli/src/lib.rs
+++ b/cli/src/lib.rs
@@ -1036,7 +1036,11 @@ fn init(
     if solidity {
         solidity_template::create_program(&project_name)?;
     } else {
-        rust_template::create_program(&project_name, template)?;
+        rust_template::create_program(
+            &project_name,
+            template,
+            TestTemplate::Mollusk == test_template,
+        )?;
     }
 
     // Build the migrations directory.
@@ -1155,7 +1159,7 @@ fn new(
                 if solidity {
                     solidity_template::create_program(&name)?;
                 } else {
-                    rust_template::create_program(&name, template)?;
+                    rust_template::create_program(&name, template, false)?;
                 }
 
                 programs.insert(
diff --git a/cli/src/rust_template.rs b/cli/src/rust_template.rs
index a8c954bf64..be11e7c28d 100644
--- a/cli/src/rust_template.rs
+++ b/cli/src/rust_template.rs
@@ -29,11 +29,14 @@ pub enum ProgramTemplate {
 }
 
 /// Create a program from the given name and template.
-pub fn create_program(name: &str, template: ProgramTemplate) -> Result<()> {
+pub fn create_program(name: &str, template: ProgramTemplate, with_mollusk: bool) -> Result<()> {
     let program_path = Path::new("programs").join(name);
     let common_files = vec![
         ("Cargo.toml".into(), workspace_manifest().into()),
-        (program_path.join("Cargo.toml"), cargo_toml(name)),
+        (
+            program_path.join("Cargo.toml"),
+            cargo_toml(name, with_mollusk),
+        ),
         (program_path.join("Xargo.toml"), xargo_toml().into()),
     ];
 
@@ -171,7 +174,17 @@ codegen-units = 1
 "#
 }
 
-fn cargo_toml(name: &str) -> String {
+fn cargo_toml(name: &str, with_mollusk: bool) -> String {
+    let test_sbf_feature = if with_mollusk { r#"test-sbf = []"# } else { "" };
+    let dev_dependencies = if with_mollusk {
+        r#"
+[dev-dependencies]
+mollusk-svm = "=0.0.6-solana-1.18"
+"#
+    } else {
+        ""
+    };
+
     format!(
         r#"[package]
 name = "{0}"
@@ -190,13 +203,17 @@ no-entrypoint = []
 no-idl = []
 no-log-ix-name = []
 idl-build = ["anchor-lang/idl-build"]
+{2}
 
 [dependencies]
-anchor-lang = "{2}"
+anchor-lang = "{3}"
+{4}
 "#,
         name,
         name.to_snake_case(),
+        test_sbf_feature,
         VERSION,
+        dev_dependencies,
     )
 }
 
@@ -610,6 +627,8 @@ pub enum TestTemplate {
     Jest,
     /// Generate template for Rust unit-test
     Rust,
+    /// Generate template for Mollusk Rust unit-test
+    Mollusk,
 }
 
 impl TestTemplate {
@@ -636,6 +655,7 @@ impl TestTemplate {
                 }
             }
             Self::Rust => "cargo test".to_owned(),
+            Self::Mollusk => "cargo test-sbf".to_owned(),
         }
     }
 
@@ -707,6 +727,19 @@ impl TestTemplate {
                 ));
                 override_or_create_files(&files)?;
             }
+            Self::Mollusk => {
+                // Build the test suite.
+                let tests_path_str = format!("programs/{}/tests", &project_name);
+                let tests_path = Path::new(&tests_path_str);
+                fs::create_dir_all(tests_path)?;
+
+                let mut files = Vec::new();
+                files.extend(create_program_template_mollusk_test(
+                    project_name,
+                    tests_path,
+                ));
+                override_or_create_files(&files)?;
+            }
         }
 
         Ok(())
@@ -778,3 +811,35 @@ fn test_initialize() {{
         ),
     ]
 }
+
+/// Generate template for Mollusk Rust unit-test
+fn create_program_template_mollusk_test(name: &str, tests_path: &Path) -> Files {
+    vec![(
+        tests_path.join("test_initialize.rs"),
+        format!(
+            r#"#![cfg(feature = "test-sbf")]
+
+use {{
+    anchor_lang::{{solana_program::instruction::Instruction, InstructionData, ToAccountMetas}},
+    mollusk_svm::{{result::Check, Mollusk}},
+}};
+
+#[test]
+fn test_initialize() {{
+    let program_id = {0}::id();
+
+    let mollusk = Mollusk::new(&program_id, "{0}");
+
+    let instruction = Instruction::new_with_bytes(
+        program_id,
+        &{0}::instruction::Initialize {{}}.data(),
+        {0}::accounts::Initialize {{}}.to_account_metas(None),
+    );
+
+    mollusk.process_and_validate_instruction(&instruction, &[], &[Check::success()]);
+}}
+"#,
+            name.to_snake_case(),
+        ),
+    )]
+}