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NEWS.md

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Monocle3 1.3.7

Changes

  • Fix partition calculation when clusters are widely separated.
  • Fix possible column selection error in plot_cells().

Monocle3 1.3.0

Changes

  • Work around conflict between SingleCellExperiment and tictoc packages.
  • Fix missing DelayedArray conversion in sparse_prcomp_irlba().
  • Relax test for rowname consistency in transfer_cell_labels().
  • Update URLs in load_worm_*() functions.
  • Minor bug fixes.

Monocle3 1.2.9

Changes

  • Project data set onto a reference data set.
  • Annotation label transfer using projection.
  • Negative binomial mixed models in fit_models.
  • Use annoy nearest neighbor functions.
  • Save and load Monocle objects and dimensional reduction models.
  • Store matrix identifiers for versioning.
  • Documentation improvements.
  • Cell_data_set internal rearrangements and additions.
  • Set cluster_cells random_seed parameter default to 42.
  • Added ability to change aggregation function to aggregate_gene_expression(), and moved scaling to be compatible with multiple aggregation policies

Bug fixes

  • Fixed some plotting issues.

monocle3 1.0.0

Changes

  • Add label_principal_points option to plot_cells to assist with identifying root_pr_nodes in order_cells.

Bug fixes

  • Documentation and error reports improvements.
  • Fix fit_models tests for NA/Inf/NaNs.
  • Refine gene loadings calculations in find_gene_modules.
  • Test for convergence failure in top_markers,

monocle3 0.2.3

Changes

  • Added clear_cds parameter to choose_cells().

Bug fixes

  • Documentation and error reports improvements.
  • Fixed issue #316, top_marker()
  • Fixed issue #346, find_gene_modules()

monocle3 0.2.2

Changes

  • Added load_mm_data() to load data from matrix market sparse file and gene and cell data files.
  • Added rann.k parameter to learn_graph().
  • Added speedglm.maxiter parameter to top_marker().

Bug fixes

  • Fixed combine_cds() issues.
  • Fixed learn_graph(use_partition=FALSE) issue
  • Fixed batchelor::fastMNN(pc.input) deprecation issue
  • Fixed choose_graph_segments() issue.
  • Fixed missing gaussian family in fit_models().
  • Fixed add pseudocount to violin plot.
  • Fixed add detect_genes() to fit_models() if needed.
  • Fixed compare_models() issues.
  • Fixed check for undefined values in fit_models() formula.
  • Fixed plot_cells() plotting order issue.
  • Fixed find_gene_modules() run-to-run variation issue.
  • Fixed rlist package namespace collision.
  • Fixed allow short gene names in aggregate_gene_expression(gene_group_df).

monocle3 0.2.0

Major changes

  • Added mutual-nearest-neighbor batch correction (MNNCorrect).
  • Switched to leiden-based clustering, dropped reticulate/python dependency.
  • Added a mechanism to get the citations used during an analysis get_citations().

Other Changes

  • Added non-standard color options for plot_cell_3d.
  • Added norm_method = 'none' option for importing pre-normalized data.

Bug fixes

  • Fixed a bug that effected cell size in plot_cells_3d.
  • Added a check for illegal characters in generate_garnett_marker_file.
  • Fixed a bug in the alpha parameter in plot_cells.
  • Fixed multiple minor reported bugs.

monocle3 0.1.3

Changes

  • Added bootstrap bars to plot_percent_cells_positive().
  • Added a UMI cutoff for load_cellranger_data().
  • Added clear_cds_slots() to clear slots from a cds.
  • Added cell_stroke parameter to plot_cells.

Bug fixes

  • Fixed #154, which actually resulted from a problem in how ncenter was calculated for each partition.
  • Fixed an issue that prevents plotting cells by pseudotime when root_cells are passed to order_cells().
  • Fixed #167 - NAs from plot_genes_by_group.

monocle3 0.1.2

Changes

  • Added a NEWS.md file to track changes to the package.
  • Added a combine_cds function that will combine cell_data_sets .
  • Added a message when duplicate markers are present in generate_garnett_marker_file and option to exclude them.

Bug fixes

  • Fixed a bug that made expression matrix the wrong class with load_cellranger.