diff --git a/README.md b/README.md
index ead1566..e98d5ae 100644
--- a/README.md
+++ b/README.md
@@ -92,6 +92,9 @@ const inputFile = fs.createReadStream('./file.pdf');
 
 await cloudConvert.tasks.upload(uploadTask, inputFile, 'file.pdf');
 ```
+> **Note on custom streams**:
+The length of the stream needs to be known prior to uploading. The SDK automatically detects the file size of file-based read streams. If you are using a custom stream, you need to pass a `filesize` as fourth parameter to the `upload()` method. 
+
 
 ## Websocket Events
 
@@ -180,6 +183,15 @@ const cloudConvert = new CloudConvert('api_key', true);
 
 > Don't forget to generate MD5 Hashes for the files you will use for testing.
 
+## Setting a Region
+
+By default, the region in your [account settings](https://cloudconvert.com/dashboard/region) is used. Alternatively, you can set a fixed region:
+
+```js
+// Pass the region as third argument to the constructor
+const cloudConvert = new CloudConvert('api_key', false, 'us-east');
+```
+
 ## Contributing
 
 This section is intended for people who want to contribute to the development of this library.
diff --git a/lib/CloudConvert.ts b/lib/CloudConvert.ts
index eac1e0a..518cf50 100644
--- a/lib/CloudConvert.ts
+++ b/lib/CloudConvert.ts
@@ -16,6 +16,7 @@ export default class CloudConvert {
 
     public readonly apiKey: string;
     public readonly useSandbox: boolean;
+    public readonly region: string | null;
 
     public axios!: AxiosInstance;
     public tasks!: TasksResource;
@@ -24,9 +25,10 @@ export default class CloudConvert {
     public webhooks!: WebhooksResource;
     public signedUrls!: SignedUrlResource;
 
-    constructor(apiKey: string, useSandbox = false) {
+    constructor(apiKey: string, useSandbox = false, region = null) {
         this.apiKey = apiKey;
         this.useSandbox = useSandbox;
+        this.region = region;
 
         this.createAxiosInstance();
         this.createResources();
@@ -36,7 +38,9 @@ export default class CloudConvert {
         this.axios = axios.create({
             baseURL: this.useSandbox
                 ? 'https://api.sandbox.cloudconvert.com/v2/'
-                : 'https://api.cloudconvert.com/v2/',
+                : `https://${
+                      this.region ? this.region + '.' : ''
+                  }api.cloudconvert.com/v2/`,
             headers: {
                 Authorization: `Bearer ${this.apiKey}`,
                 'User-Agent': `cloudconvert-node/v${version} (https://github.com/cloudconvert/cloudconvert-node)`
diff --git a/lib/JobsResource.ts b/lib/JobsResource.ts
index 8734ac6..ada71e4 100644
--- a/lib/JobsResource.ts
+++ b/lib/JobsResource.ts
@@ -47,7 +47,11 @@ export default class JobsResource {
         const response = await this.cloudConvert.axios.get(`jobs/${id}`, {
             baseURL: this.cloudConvert.useSandbox
                 ? 'https://sync.api.sandbox.cloudconvert.com/v2/'
-                : 'https://sync.api.cloudconvert.com/v2/'
+                : `https://${
+                      this.cloudConvert.region
+                          ? this.cloudConvert.region + '.'
+                          : ''
+                  }sync.api.cloudconvert.com/v2/`
         });
         return response.data.data;
     }
diff --git a/lib/TasksResource.ts b/lib/TasksResource.ts
index 06ff47c..4c197bf 100644
--- a/lib/TasksResource.ts
+++ b/lib/TasksResource.ts
@@ -560,7 +560,11 @@ export default class TasksResource {
         const response = await this.cloudConvert.axios.get(`tasks/${id}`, {
             baseURL: this.cloudConvert.useSandbox
                 ? 'https://sync.api.sandbox.cloudconvert.com/v2/'
-                : 'https://sync.api.cloudconvert.com/v2/'
+                : `https://${
+                      this.cloudConvert.region
+                          ? this.cloudConvert.region + '.'
+                          : ''
+                  }sync.api.cloudconvert.com/v2/`
         });
         return response.data.data;
     }