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Cannot calculate sensitivity after PI #89

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Yuri05 opened this issue Oct 17, 2019 · 6 comments
Open

Cannot calculate sensitivity after PI #89

Yuri05 opened this issue Oct 17, 2019 · 6 comments
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@Yuri05
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Yuri05 commented Oct 17, 2019

19_15.zip

When the PI in the project attached is started: the PI itself is finished immediately. However calculation of sensitivity never ends. Probably a numerical issue.
grafik

Interestingly: one of the identification parameters is biliary plasma clearance. In the original simulation it is set to 0. In the PI it is set to fixed with initial value 0 (thus it has no effect on optimization results). But if Bil_PLS is removed from the list of identification parameters: sensitivity can be calculated.

grafik
@msevestre
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@Yuri05 looks more like a SimModel issue no?

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Yuri05 commented Oct 17, 2019

With high probability: yes

@Yuri05
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Yuri05 commented Oct 17, 2019

@UlrichSi FYI

@msevestre msevestre transferred this issue from Open-Systems-Pharmacology/OSPSuite.Core Oct 17, 2019
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Then moving :)

@PavelBal
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@Yuri05 What is the status on this? We are also running into this problem now and then...

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Yuri05 commented Jul 23, 2021

What is the status on this?

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