diff --git a/README.rst b/README.rst
index 38d9c24..96bba48 100644
--- a/README.rst
+++ b/README.rst
@@ -30,6 +30,17 @@ flake8 configuration (e.g. your ``.flake8`` file):
     [flake8]
     dictionaries=en_US,python,technical,django
 
+Enable pandas support
+---------------------
+
+You can enable support for pandas DataFrames by adding the following to your
+flake8 configuration (e.g. your ``.flake8`` file):
+
+.. code-block:: ini
+
+    [flake8]
+    dictionaries=en_US,python,technical,pandas
+
 
 Specify Targets
 ---------------
@@ -61,6 +72,7 @@ adding those word(s) to the appropriate dictionaries:
 * `python dictionary <flake8_spellcheck/python.txt>`_
 * `technical dictionary <flake8_spellcheck/technical.txt>`_
 * `django dictionary <flake8_spellcheck/django.txt>`_
+* `pandas dictionary <flake8_spellcheck/pandas.txt>`_
 
 Before you submit a PR, it is recommended to run ``check-sorting.sh`` in the root of this repository,
 to verify that all the dictionary files are still sorted correctly. Sorting is enforced by CI, so
diff --git a/flake8_spellcheck/pandas.txt b/flake8_spellcheck/pandas.txt
new file mode 100644
index 0000000..ece770f
--- /dev/null
+++ b/flake8_spellcheck/pandas.txt
@@ -0,0 +1,61 @@
+agg
+applymap
+asfreq
+asof
+astype
+backfill
+bfill
+boxplot
+corrwith
+cov
+csv
+cummax
+cummin
+cumprod
+cumsum
+droplevel
+dropna
+dtypes
+ewm
+ffill
+fillna
+floordiv
+gbq
+groupby
+hdf
+iat
+idxmax
+idxmin
+iloc
+isin
+isna
+iterrows
+itertuples
+kurtosis
+mul
+ndim
+nlargest
+notna
+notnull
+nsmallest
+numpy
+nunique
+quantile
+radd
+rdiv
+reindex
+resample
+rfloordiv
+rmod
+rmul
+rpow
+rsub
+rtruediv
+sem
+stata
+swapaxes
+swaplevel
+truediv
+tshift
+unstack
+xarray