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DESCRIPTION
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DESCRIPTION
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Package: TranscriptomeReconstructoR
Title: Data-driven Annotation of the Transcriptome
Version: 1.0.0
Authors@R:
person(given = "Maxim",
family = "Ivanov",
role = c("aut", "cre"),
email = "[email protected]",
comment = c(ORCID = "0000-0001-7548-3316"))
Description: This package reconstructs the most probable gene/transcript model for a species
by combining a few orthogonal high throughput sequencing datasets. The three
essential datasets are as follows: i) 5' tag RNA sequencing dataset which shows
TSS (transcription start sites), e.g. CAGE; ii) 3' tag RNA sequencing dataset
which shows PAS (polyadenylation sites); iii) Full-length RNA sequencing dataset
which shows splicing patterns (e.g. Direct RNA-seq on Oxford Nanopore).
Optionally, a nascent RNA-seq dataset (e.g. NET-seq or GRO-seq) can be added to
resolve the transient non-coding transcripts.
License: `use_gpl3_license()`
Encoding: UTF-8
LazyData: true
Roxygen: list(markdown = TRUE)
RoxygenNote: 7.1.1
Imports:
GenomicRanges,
GenomicAlignments,
rtracklayer,
tidyverse,
collections,
methods
Suggests:
knitr,
rmarkdown
VignetteBuilder: knitr
BiocViews: Software, Transcription, Transcriptomics, Sequencing, Annotation, GenomeBrowsers