diff --git a/eb_hooks.py b/eb_hooks.py
index 31f2b9588d..3147fc9bf5 100644
--- a/eb_hooks.py
+++ b/eb_hooks.py
@@ -268,6 +268,22 @@ def pre_configure_hook_wrf_aarch64(self, *args, **kwargs):
         raise EasyBuildError("WRF-specific hook triggered for non-WRF easyconfig?!")
 
 
+def pre_configure_hook_PLUMED_aarch64(self, *args, **kwargs):
+    """
+    pre-configure hook for PLUMED:
+    - remove unsupported --enable-asmjit option on aarch64
+    """
+
+    if self.name == 'PLUMED':
+        if  get_cpu_architecture() == AARCH64:
+            configopts = self.cfg['configopts']
+            regex = re.compile(r'--enable-asmjit')
+            if re.search(regex, configopts):
+                self.cfg['configopts'] = regex.sub('', configopts)
+    else:
+        raise EasyBuildError("PLUMED-specific hook triggered for non-PLUMED easyconfig?!")
+
+
 def pre_test_hook(self,*args, **kwargs):
     """Main pre-test hook: trigger custom functions based on software name."""
     if self.name in PRE_TEST_HOOKS:
@@ -346,6 +362,7 @@ def pre_single_extension_isoband(ext, *args, **kwargs):
     'MetaBAT': pre_configure_hook_metabat_filtered_zlib_dep,
     'OpenBLAS': pre_configure_hook_openblas_optarch_generic,
     'WRF': pre_configure_hook_wrf_aarch64,
+    'PLUMED': pre_configure_hook_PLUMED_aarch64,
 }
 
 PRE_TEST_HOOKS = {